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Biomedical subjects

E Wulf

Publications and source records attributed to E Wulf.

30 records · Page 2Linked to original sources
PubMed1979

[The binding of dyes of fibrinogen].

Examinations performed by means of the agargel-electrophoresis, immunoelectrophoresis, discelectrophoresis, and chromatography on gel in human plasma and preparations of fibrinogen revealed that fibrinogen will form complexes with 18 examined dyes of different chemical structure, from a total amounting to 46. The findings indicate a marked affinity of fibrinogen towards small molecules in general. In nearly all complex forming colour materials, fibrinogen could be identified by immunodiffusion in the colour-blood supernatant liquid. The physiological significance of the binding capacity of fibrinogen is discussed.

Animals↗
PubMed1977

[Investigation on the detection of circulating antibodies in yoshida-sarcoma bearing rats by the serologic-nephelometric method of Hoigné (author's transl)].

Circulating antibodies against tumour antigens were detected by means of the serologic-nephelometric method of Hoigné et al. (1955). Under employment of homogenates of tumour tissue as antigen solutions in 95 per cent of the cases the sera of Yoshida-sarcoma bearing rats reacted positively, while only in 4 per cent of the normal animals a positive reaction was found. 11 per cent of tumour-bearing animals showed in addition positive reactions against the normal muscle tissue, normal rats reacted positively in 2 per cent of the cases. In 93 per cent the sera of tumour-bearing animals reacted with spleen homogenates of sarcoma-bearing rats positively, whereas serum of normal rats showed 20 per cent positive reactions with the same antigen. The results confirm the aptitude of the serologicnephelometric method of Hoigné et al. (1955) and of the employed animal model for investigations of tumour-immunological problems, and they underline the antigenicity of the Yoshida-sarcoma.

Animals↗
PubMed1976

[Comparative study on lymphocyte stimulation by PHA and bacterial endotoxins, particularly in malignant tumor and allergy patients].

In a group of 37 tumor patients with predominantly advanced disease, LPS stimulation (LPS of Sh. sonnei and Sh. flexneri) resulted in a significant increase of the transformation rates caused, most probably, by the high proportion of B cells. On the other hand, allergics (drug allergies) did not differ from controls. It seems possible that B cell stimulation by bacterial endotoxins can be used for the assessment of the reactivity of the organism.

Adult↗