The telencephalon saved by TLC.
The telencephalon is one of the most complex parts of the brain, and its patterning is still poorly understood. In this issue of Neuron, describe a novel Wnt antagonist Tlc, a member of the secreted Frizzled-related protein (sFrp) family. Secreted from the anterior boundary of the zebrafish neural plate, Tlc appears to protect the telencephalon from obliteration by a more caudal neural Wnt signal.
Animals↗