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PubMed · 12160739

The telencephalon saved by TLC.

Elizabeth Grove
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Abstract

The telencephalon is one of the most complex parts of the brain, and its patterning is still poorly understood. In this issue of Neuron, describe a novel Wnt antagonist Tlc, a member of the secreted Frizzled-related protein (sFrp) family. Secreted from the anterior boundary of the zebrafish neural plate, Tlc appears to protect the telencephalon from obliteration by a more caudal neural Wnt signal.

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AnimalsBody PatterningGene Expression Regulation, DevelopmentalIntracellular Signaling Peptides and ProteinsProteinsProto-Oncogene ProteinsSignal TransductionTelencephalonWnt ProteinsZebrafishZebrafish ProteinsFrizzled-Related ProteinsJournal ArticleReviewComment

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Elizabeth Grove. 2002-07-18. The telencephalon saved by TLC.. https://doi.org/10.1016/s0896-6273(02)00779-1

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