Some novel theophylline thiosemicarbazide and thiazolidinone derivatives as potential anticancer and anticonvulsant agents.
Explore the source record for details and available documents.
Animals↗
Biomedical subjects
F A Ashour
Publications and source records attributed to F A Ashour.
Synthesis of some alkoxybenzamide derivatives as smooth muscle relaxant agents.
The preparation of 16 new N-substituted p-aminobenzamide derivatives which contain diethylaminoethyl-N-methylpiperazine, piperidine and morpholine moieties were described. Preliminary pharmacological testing of representative compounds showed that some of the prepared compounds possess anticholinergic and antihistaminic activities.
Animals↗
Synthesis and pharmacological testing on some theophylline esters.
Esters of theophylline-7-acetic acid with different amino alcohols were prepared as possible atropine substitutes, together with esters of some hydroxy acids with beta-hydroxyethyl theophylline. Moreover, esters possessing both theophyllinyl and piperazinyl moieties were prepared with the hope that their spasmolytic activity might be increased. Some of the prepared compounds proved to possess atropine-like activity.
Acetylcholine↗