Biomedical subjects

F Basile

Publications and source records attributed to F Basile.

97 records · Page 6Linked to original sources

PubMedDate not supplied

[Surgical treatment of carcinoma in situ of the breast].

After briefly mentioning the incidence of in situ breast carcinoma and the importance of mammography as an instrument of early diagnosis, the Authors inspect their own case notes and discuss indications and problematical characters linked to the various surgical techniques. It is concluded that, in case of a not infiltrating mammary carcinoma, it is possible to entertain an adequate conservative surgical treatment on condition that it is always associated to a modern and effective radiotherapy of the remaining mammary parenchyma and that it is feasible an attentive and extended follow-up; when even only one of these two conditions is not practicable or in the presence of cancer-phobic patients, the alternative of a unilateral or bilateral subcutaneous mastectomy, followed by an immediate reconstruction with an implant, does remain efficacious both on the oncological and esthetic point of view.

Adult↗

PubMedDate not supplied

[Postanal repair in the treatment of idiopathic neurogenic fecal incontinence].

Faecal incontinence is an important disabling symptom in the affected patients. Classically, we divide faecal incontinence in two main types: traumatic faecal incontinence and neurogenic faecal incontinence. Neurogenic faecal incontinence is characterized by a diffuse weakness of anal sphincter and of the elevator muscles. The aim of the present study was to evaluate the outcome of postanal repair procedure in the management of neurogenic faecal incontinence. To this end we studied 20 patients with neurogenic faecal incontinence who underwent a postanal repair procedure according to the method described by Parks. Mean follow up was up two years and was based mainly both on clinical evaluation and manometric values carried out on a 6 monthly basis. When the outcome was evaluated in terms of faecal incontinence our date were similar to those reported by Parks and Keighley. In the subjects studied we haven't reported any major complications apart from two cases of wound's infection which were efficaciously treated. Our findings supported the view that postanal repair procedure is the surgical approach of choice in the patients with idiopathic neurogenic faecal incontinence.

Anal Canal↗

PubMedDate not supplied

[Treatment of primary gastric lymphoma in IE/IIE stages].

The primitive gastric lymphoma constitutes 2-5% of malignant gastric neoplasms. The present treatment of such a pathology is not defined, since it seems that this disease deserves a multidisciplinary approach: surgical, chemotherapical, radiotherapical. The authors by means of this study, intend to estimate the results of the therapeutic treatment employed in 18 patients suffering from primitive gastric lymphoma in the stage IE and IIE. From the results obtained by our study, it emerges that in the lymphomata located in the cavity at the stage IE, there takes place the almost total superimposition of the results, in terms of survival to 5 years, in the patients treated surgically and in those treated by chemotherapy. Therefore, in such cases the chemotherapic treatment can be proposed because it is bloodless, the patient appreciates it more and it seems to be accompanied by a very small number of complications. In the patients with lymphomat located in the antrum at the stage IIE, we have obtained good results in terms of survival joining radiotherapy and chemotherapy to surgery, as reported by Moore. Even taking into account the very small number of cases we have considered, we think the primitive gastric lymphoma at the stage IE must be treated by means of chemotherapy, while that one at the stage IIE requires and integrated treatment.

Female↗

PubMedDate not supplied

[The usefulness of thyroxine treatment after subtotal thyroidectomy for endemic goiter].

The aim of the present study was to assess the appropriateness and value of prophylactic thyroxine therapy in the treatment of postoperative complications (relapse, postoperative hypothyroidism) following subtotal thyroidectomy for endemic goiter. The study was carried out in a group of 139 patients undergoing subtotal thyroidectomy for endemic goiter between 1978 and 1987. Clinical follow-up included hematochemical and scintigraphic analyses. Patients were divided into two groups. The first group included 74 patients who received postoperative hormone replacement therapy. The second group of 65 patients did not receive any treatment. results show that hormone replacement therapy is unnecessary in most cases since the majority of patients require euthyroid values a few months after operation. Thyroxine therapy was indicated, however, in cases of clinically evident postoperative hypothyroidism which persisted during follow-up.

Adult↗

PubMedDate not supplied

[Technic of overlapping sphincter anal repair in the treatment of traumatic anal incontinence].

Faecal incontinence is an important disabling symptom in the affected patients. Classically, we divide faecal incontinence in two main types: neurogenic faecal incontinence and traumatic anal incontinence. Traumatic anal incontinence is due to causes damaging sphincteric mechanism directly. The aim of the present study was to evaluate the outcome of overlapping sphincter anal repair procedure in the management of traumatic anal incontinence. To this end we studied 27 patients with traumatic anal incontinence who underwent an overlapping sphincter anal repair procedure according to the method described by Parks and McPartlin in 1971. Mean follow up was up three years and was based mainly both on clinical evaluation with anorectal exploration and manometric values carried out on a 6 monthly basis. When the outcome was evaluated in terms of faecal continence our date were similar to those reported by Parks and Fang. In the subjects studied we haven't reported any major complications apart from one case of abscess, one case of wound's infection and one case of stenosis which were efficaciously treated. Our findings supported the view that overlapping sphincter anal repair procedure is the surgical approach of choice in the patients with traumatic anal incontinence.

Anal Canal↗

PubMedDate not supplied

[Phyllodes tumor of the breast: diagnostic and therapeutic problems].

Phyllodes tumour (PT) is a rare breast tumor with mixed connective and epithelial components, which usually relapses topically after excision. Five patients with PT took part in the study (4 were positive for benign PT and one was positive for malignant PT at extemporary histological examination). The patients (3) with 3 cm or minus benign lesion had mass excision with a large resection of the surrounding mammary tissue. In the remaining patient with benign neoplasm (8 cm lesion) simple mastectomy was carried out. Finally the patient with malignant PT (5 cm lesion) underwent a simple mastectomy without following chemotherapy or radiotherapy. Follow-up (at 6 and 12 months) consisted of mammography and clinical examination. One out of the 3 patients treated with large resection had a local relapse which was then treated surgically. There was no evidence of relapse at 12 months in the remaining patients with benign tumor. The patient with malignant PT returned to our attention with multiple bone metastases in the thoracic lumbar tract two years later. She received multiple courses of combined radiotherapy and chemotherapy. Local relapses do not appear to affect survival: as a consequence, wide excision should be the primary treatment of benign phyllodes tumors. Total mastectomy has been indicated for malignant phyllodes tumors and for very large tumors.

Adult↗

PubMedDate not supplied

[Early gastric cancer: our experience].

The early gastric cancer (EGC) is a very interesting pathology as it represents the first phase of gastric cancer, curable in most cases. The aim of the present study is to evaluate the outcome of surgical treatment of EGC in 19 consecutive patients. The studied patients were followed up for 5 years, during which they underwent a gastroscopy, a hepatic echography and a TC at one year intervals in case of echographic suspicion. Ten patients with limited involvement of the antrum underwent a gastric resection with Billroth II's reconstruction; five patients with circumscribed involvement of the gastric body underwent a subtotal resection; four patients (one with a multifocal involvement of the gastric body and three with multifocal involvement of the fundus) underwent a total gastrectomy with Roux's reconstruction. All patients underwent a limited lymphadenectomy of the perigastric lymph nodes. By evaluating and comparing the results of the present study with previous data on EGC, we propose gastric resection, subtotal gastrectomy and total gastrectomy, according to the location of neoplasm, with limited lymphadenectomy of perigastric lymph nodes.

Adenocarcinoma↗