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Biomedical subjects

F Bläker

Publications and source records attributed to F Bläker.

At least 19 recordsLinked to original sources
PubMed1991

[Evaluation of a rapid test for direct detection of group A streptococcal antigen in throat swabs. Study of 4 commercial test systems].

Four commercially prepared test reagent kits for the rapid screening of throat swabs for group A streptococci were examined in comparison to bacteriological cultures of 963 double throat swabs. The sensitivities of the test systems were 86.7% (Abbott Test Pack Strep A), 81.8% (Hybritech Tandem Icon Strep A), 79.6% (Pharmacia Phadirect Strep A), and 72.6% (Wellcome Reveal Colour Strep A) respectively. The specificity of the four tests was above 90%. Marked variations between different test reagent batches could be observed. The two tests based on the enzyme immunoassay principle proved to be superior to the agglutination tests investigated with respect to sensitivity and reading accuracy. Our results are evaluated in the light of the published literature on these tests.

Antigens, Bacterial↗
PubMed1986

Influence of haemodialysis and renal transplantation on trace element concentrations in children with chronic renal failure.

Whole blood levels of Cd and Pb (microgram/g Hb), serum concentrations of Sr and Zn and their urinary excretion were measured in healthy, renal transplant and dialyzed children by atomic absorption spectroscopy. Furthermore, before and after dialysis the concentrations of these elements were determined in blood/serum as well as in the dialysis fluid. The predialytic concentrations of Cd, Pb and Sr in blood/serum were significantly increased compared to controls. Haemodialysis had only minor effects on whole blood Cd and Pb levels but serum Sr and Zn concentrations increased as a result of high metal levels in dialysis fluid. Children after renal transplantation showed no alterations in Pb, Sr and Zn concentrations compared to healthy children but whole blood Cd was increased. According to the renal function the Pb, Cd and Zn urinary excretion decreased in the following order: healthy, renal transplant and dialysis children. Sr urinary excretion was increased in haemodialysis and renal transplant patients. In conclusion, we found no Zn deficiency. Elevated blood levels of Cd and Pb and elevated Sr serum concentrations in paediatric patients undergoing dialysis and increased Cd whole blood levels in renal transplant children could be of clinical interest.

Adolescent↗
PubMed1984

[Results and specific problems in unrestricted indications for kidney transplantation in children].

In Hamburg 22 children had 33 renal transplantations in the time from 1976 till 1982. 58% of all children in this area with end-stage renal disease have now a functioning graft compared to only 11% of the adult patients. This is the result of preferred transplantation in children whenever possible. Retransplantation was more frequent in children (32%) than in adults (19%). 5 years function rate of renal allografts is significantly worse in children than in adults. Growth and degree of rehabilitation are described in 12 pediatric renal allograft recipients who survived with a functioning graft for at least 3 years. Good rehabilitation as indicated by attendance of school and employment was reached in 83% of these patients. Different growth patterns occurred. Clinical factors associated with growth performance include graft function and age at the time of transplantation.

Adolescent↗
PubMed1981

Infantile periarteritis nodosa. Case report and review of the literature.

The clinical and autopsy findings of a three-month-old male infant with infantile periarteritis nodosa are described adn the literature reviewed. Different stages of the inflammatory vascular process could be seen in the iliacal, axillary, carotidal, coronary and the small periadrenal-tissue-arteries. Secondary changes were found in the axillary and coronary arteries consisting of aneurysmal dilatation and thrombosis. Fatal myocardial infarction occurred thirty-nine days following hospital admission.

Autopsy↗