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PubMed1982

[Palliative urinary diversion in cases of cancer of the pelvis].

The introduction of percutaneous nephrostomy under xc-ray control or ultra-sonic control makes it possible to do the operation even in patients with a bad general condition. The decision for palliative urinary diversion in cases of cancer of the pelvis is therefore largely an ethical question. A group of patients with palliative urinary diversion (n = 48) was compared to a group with iatrogenic obstruction of the urinary tracts but without recurrence of carcinoma (n = 26). Six months later only 23 of the 48 Patients in the palliative group were alive, whereas 23 of the 26 patients without recurrence of cancer were alive. After 24 months, 35 of the 48 patients with incurable cancer had died. The indications are listed.

Adult↗

PubMedDate not supplied

[Significance of pathological alpha-1-fetoprotein levels in the framework of prenatal diagnosis].

Merkatz (1984) showed that in 68% of live birth with Down Syndrome maternal age was 34 years or less. It would be desirable to define a high risk collective of women younger then 35 years with the help of a screening test, which could further on lead to a prenatal diagnostics. Several studies showed that low maternal serum alpha-fetoprotein levels (SAFP) in pregnancy is associated with fetal chromosomal abnormalities. The results of a retrospective study at the Department of Obstetrics and Gynecology at University of Mainz showed that maternal SAFP-level does not accomplish the demand of a prenatal screening test, because only 17% of the Down Syndrome could be diagnosed by this parameter. In case of trisomy 13 and 18 SAFP-concentrations were normal or even increased, maybe on account of the combination with other malformations like neural-tube or abdominal-wall defects.

Adult↗