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Biomedical subjects

F Ebner

Publications and source records attributed to F Ebner.

At least 109 records · Page 6Linked to original sources
PubMed1985

Potassium changes the relationship between receptor occupancy and the inotropic effect of cardiac glycosides in guinea-pig myocardium.

K+ (2.4-15.6 mmol l-1) antagonized the positive inotropic effect of dihydro-ouabain. The concentration-effect curves became steeper with the shift to higher concentrations of the glycoside. At 1.2 mmol l-1 Ca2+, an increase in K+ from 2.4 to 12 mmol l-1 required tenfold higher concentrations of dihydro-ouabain to produce equal inotropic effects. This factor was reduced to four at 3.2 mmol l-1 Ca2+. The same change in K+ concentration, at 1.2 mmol l-1 Ca2+, diminished the inotropic effect of ouabain on rested-state contractions by a factor of six. The positive inotropic effect of Ca2+ was also antagonized by K+ (1.2-12 mmol l-1). Reduction of Na+ from 140 to 70 mmol l-1 abolished the antagonistic action of K+ (1.2-8.0 mmol l-1). Moreover the inotropic effect of Ca2+ was enhanced. Reduction of Na+, from 140 to 70 mmol l-1, antagonized the positive inotropic effect of dihydro-ouabain more at low (2.4 mmol l-1) than at high (8.0 mmol l-1) K+. Accordingly, the extent of the dihydro-ouabain-K+ antagonism was reduced. When the K+ concentration was increased from 2.4 to 12 mmol l-1, [3H]-ouabain binding was reduced by a factor of three. This is less than the reduction in the inotropic effectiveness of ouabain or dihydro-ouabain. Reduction of stimulation frequency from 1 to 0.1215 Hz did not significantly alter the antagonistic effect of K+. Diminution of Vmax of the action potential was observed only at K+ concentrations greater than 5.9 mmol l-1, whereas the resting membrane potential was continuously depolarized over the entire range of K+ concentrations. The results support the view that the reduction in receptor affinity cannot be the sole cause of the antagonism between the glycoside and K+. Impairment of passive Na+ influx during diastole, due to the K+-dependent depolarization of the resting membrane potential, contributed to about one half of the glycoside-K+ antagonism.

Animals↗
PubMed1985

[Adrenal masses--diagnostic ranking of methods].

The ultrasonographic, computertomographic and angiographic findings of 87 patients with adrenal tumours were analysed retrospectively. Histologically, 16 adrenal adenomas, 6 carcinomas, 4 cysts, 5 pheochromocytomas, 3 neuroblastomas and 1 myelolipoma were found. Adrenal metastases were present in 52 cases. Dependent on clinical symptoms and the expected pathological findings, the radiological procedure varies. The diagnostic accuracy of the various methods is compared.

Adenoma↗
PubMed1985

[Ischemic necrosis of the vertebral body].

The article reports on the x-ray signs of ischaemic necrosis of vertebral bodies, basing on a case history. The aetiology of this rare condition is discussed and the relevant literature is reviewed.

Aged↗
PubMed1984

[Sonographic visualization of the left ovarian vein. A contribution to the diagnosis of compression syndrome of the left renal vein].

Amongst 737 sonographic and CT examinations of women aged 18 to 60 years of age, seven cases of ectasia of the left ovarian vein were found (0.95%). The aetiology and significance of this finding in the context of the "compression syndrome of the left renal vein" are discussed. The value to sonography in elucidating this condition is stressed.

Adolescent↗
PubMed1984

[Sonographic demonstration of an ectopic ureter orifice].

In a case report an ectopic ureter evaluated by means of ultrasound and proved by surgery is discussed with respect to its embryologic development, incidence and clinical aspects. Sonography is shown to be of diagnostic value in localizing the orifice of an ectopic ureter.

Adult↗
PubMed1983

[Therapeutic embolization with polyvinyl alcohol (Ivalon). Clinical experiences].

Polyvinyl alcohol is rigid foam used in pressed or unpressed form for the purpose of embolisation. It is suitable for both micro-embolisation in the vascular periphery and for central vascular occlusion. Polyvinyl alcohol will result in permanent vascular occlusion. Basing on the experience collected with 71 embolizations, the article reports on the technique applied and on the results obtained with craniofacial, thoracic, abdominal, pelvic and peripheral embolisation.

Adolescent↗
PubMed1983

[Percutaneous transthoracic fine-needle biopsy of the lung. Indications, results and complications in 578 punctures].

578 fine-needle biopsies of lung lesions in 319 patients were performed. This investigation was mainly done by means of Rotex-biopsy instruments. The procedure proved to be efficient in 84%, complicated in 19,7% of the patients. Major complications were seen in 5,6% only. Percutaneous needle biopsy in appropriate for obtaining a cytological diagnosis to clarify the etiology of localized lung lesions.

Adolescent↗