[The electrospinogram in the rabbit: normative data and acute lesions].
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Biomedical subjects
Publications and source records attributed to F Greco.
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The electrospinogram was investigated in 18 adult rabbits before and after acute spinal lesions of variable entity. The first positive wave is widely distributed from L7 to Th11-12 and seems to be generated by a dipole placed within the cauda. The following 'M'-shaped complex is propagated up to the cervical segments probably along the primary afferent pathways in the dorsal columns ipsilateral to the stimulated side. Local reflexes of mono- and polysynaptic loops are also present. Standardized seriate clinical observations did not provide reliable data on level and extension of the lesion until 16-24 h, while the electrospinogram showed a 'killed end' potential already within the first 60 min. Furthermore, this noninvasive test furnishes early tools about the width of the anatomical damage.
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Somatosensory evoked potentials (S.E.P.) were used to examine twelve patients who had slow compressive lesions of the spinal cord (ten cases of spondylotic myelopathy, one neurinoma, one metastasis of a vertebral body). 73 per cent of the recordings were found to be abnormally reduced in amplitude, and/or showed prolonged latency times aa regards the primary and secondary complex. Patients with a clinical lesion of the dorsal column showed a clear reduction in amplitude in the recordings (sometimes coupled with slowed latency), especially in the primary complex. Patients with symptoms indicative of an injury to the ventrolateral region of the spinal cord showed tracings with alterations most of all related to the secondary complex. In 76 per cent of cases, the somatosensory evoked potentials were in accordance with the level of the compression, the degree of invalidity, and the clinical picture.
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The authors assert the usefulness of the scintigraphy in the early diagnosis and/or for the confirmation of the main complications connected with the artroprosthesis of the hip. Such investigation is effective only if it is carried out at a distance of at least six months from the operation and must be completed by clinical, bio-humoral and radiographic tests. This study is based on the observation of 40 cases, of which 20 represent the control group. The isotope used is the Tc99m-pyrophosphate.
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