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Biomedical subjects

F Guilbert

Publications and source records attributed to F Guilbert.

At least 91 records · Page 5Linked to original sources
PubMed1988

[Genioplasty, indications and therapeutic methods in dento-maxillary malformations].

Genioplasty constitutes an adjunctive surgical procedure used in adult plastic surgery of the facial profile. It is used after dental malocclusion has been corrected and facial morphological features have been reassessed (soft tissue changes consecutive to maxillary osteotomy should be previously analyzed by cephalometry). Genioplasty permits achieving a modification of the chin point in the three planes. The authors describe several types of genioplastic operations, depending on the aim.

Adult↗
PubMed1987

[Pleomorphic adenoma. Diagnostic difficulties. Value of ultrastructural and immunohistochemical studies. Apropos of 2 cases].

2 cases of pleomorphic adenoma with unusual histological feature are related. In the 1st case, the tumor was mistaken for a schwannoma. The electron microscopic study only permitted the diagnosis; in the 2nd case, the tumor, obviously malignant, was firstly diagnosed as synovial sarcoma; in this case also, ultrastructural study permitted to recognize a malignant mixed tumor with an unusual "sarcomatous" change of its myoepithelial component.

Adenoma, Pleomorphic↗
PubMed1987

[Fibrous dysplasia and ossifying fibroma. Morphologic criteria].

Among a series of 42 ossifying fibromas and 32 fibrous dysplasias, 5 cases were studied by histoenzymological and electron microscopic methods. The histological study in 2/3 of cases is sufficient for the diagnosis between the two diseases: trabecular bone in a connective tissue with regular collagen fibres in the ossifying fibroma; nodular indented bony areas with irregular collagen frame in fibrous dysplasia. By histoenzymology, the diagnosis between the two affections is not easy: same activity of ATPases and alkaline phosphatases in fibroblasts and osteoblasts. By electron microscopy, the morphology of the two lesions is different: in ossifying fibroma, numerous well-differentiated osteoblasts and large areas of ossification are seen; in fibrous dysplasia, undifferentiated cells are numerous and the collagen frame is irregularly mineralized. This method is also useful for the histogenetic understanding of these two osteopathies.

Collagen↗
PubMed1987

[Reconstruction following anterior sulco-mandibulectomy. The advantages and disadvantages of different procedures. Apropos of 85 cases].

A retrospective study was conducted on 85 case-reports of patients with epithelioma of anterior and anterolateral region of floor of mouth operated upon in the Stomatology and Maxillofacial Surgery Clinic of Salpêtrière hospital, Paris. An update review of recent advances in surgery for reconstruction of floor of mouth is completed by results of study of the case-reports showing evolution of ideas related to functional results and to vital prognosis (as function of tumoral stage).

Adult↗
PubMed1987

[Malignant xanthogranuloma of the cervicofacial region. Optical and ultrastructural morphology. Apropos of 4 cases].

The 4 cases of malignant xanthogranuloma reported here are peculiar because of their unusual localization in the cervico-facial area and of their good outcome (3 patients are alive without recurrence more than 6 years after chemotherapy and radiotherapy). Besides the histological study, the 4 cases were examined by immunohistochemical methods : vimentin was positive in 20 to 40% of cells and lysozyme in 5 to 15% of cells. In addition, one case was studied by electron microscope which showed the polymorphism of tumoral cells.

Adult↗
PubMed1987

[Histiocytosis X of the jaw. I. Anatomico-clinical study apropos of 61 cases].

61 cases of histiocytosis X of jaws were reported here. They occurred more often in man (72% of men) than in woman, with an average age of 27 years. The mandible was affected more frequently than the maxilla. Clinically, dental expulsion, gingival swelling, fractures or pain were the usual symptoms. Roentgenographic examination showed either central or peripheral (alveolar bone) osteolytic areas. The histologic diagnosis was easy when eosinophilic polymorphous leukocytes or histiocytes were preponderant. In the other cases, immunohistochemistry (positivity of S-100 protein) and electron microscopy (presence of Birbeck granules about paraffin embedded specimens) were of a great usefulness. The prognosis of the disease was mainly related to the diffusion of lesions to other skeletal portions or extraskeletal localizations (37% of our cases). It has been improved by combination of chemotherapy to surgery (despite of frequent recurrences), 40 upon 45 patients are well after a follow-up of 2 to 10 years after the last localization.

Adolescent↗
PubMed1986

[Neural tumors of the tongue. An anatomicoclinical study apropos of 13 cases].

During the ten last years, 13 neural tumors of the tongue have been observed in the department of stomatology and maxillo-facial surgery of Salpêtrière Hospital Paris (Prof. J.M. Vaillant): 4 amputation neuromas, 5 benign schwannomas, 1 malignant schwannoma, 2 neurofibromas and 1 multiple endocrine syndrome type III. The authors analyze the clinical and histological data from these case-reports; they point out difficulties encountered in the diagnosis, and the prognostic problems brought up by such infrequent lesions.

Adolescent↗
PubMed1986

[Approach to age determination based on dental morphological criteria obtained in microradiography, stereomicroscopy and scanning electron microscopy].

The determination of the age owing to the morphology of permanent teeth has been done in 14 men and women, using criteria proposed by Gustafson. It was faithful, the difference between age determined by this method and the true age of these patients being never superior to 3 years. The application of scanning electron microscopy allows to improve some of the criteria used for this determination, especially that based upon the dentinal senescence.

Adult↗
PubMed1986

[Ameloblastoma in an 11-year-old child].

The authors report a case of ameloblastoma occurring at the unusual age of 11 years. The surgical management is conservative. Complete and careful tumorectomy was performed without reconstruction. Complete spontaneous restitution was seen one year after the operation. No recurrence was seen and the patient may new be considered as cured, with a 6 year follow-up.

Ameloblastoma↗
PubMed1986

[Odontogenic myxoma. A histoenzymologic and ultrastructural study. Apropos of 5 cases].

The myxoma of the jaws represent 8% of the odontogenic tumours in our series (324 cases). The 5 cases described here were studied by histoenzymological and electron microscopic methods. The first method demonstrated in the majority of tumoral cells a high level of activity of alkaline phosphatases and ATPases similar to that noted in odontoblasts of the dental pulp. In addition, an acid phosphatase activity was also present in numerous cells but usually at a low intensity. Ultrastructurally, the tumour was composed of 3 main cellular types: young round cells with numerous ribosomes; stellate secretory cells with well-developed granular ergastoplasma and Golgi apparatus; fusiform cells with characteristics of fibroblasts. Some macrophages and myofibroblasts were also present. The intercellular substance was granulofilamentous and in one of our cases calcifications were obvious upon some collagen fibers. All these results seem to corroborate the hypothesis of odontogenic nature of the tumour. Early odontogenic induction induces the transformation of fibroblasts into cells with enzymatic activities similar to those of odontoblasts and the calcification of collagen fibers seen in one of our cases would express an early mineralization.

Esterases↗
PubMed1985

[Angiomas of the jaws. Diagnostic and therapeutic problems (apropos 12 cases)].

Difficulties encountered during surgery on maxillary angiodysplasias were studied in relation to case-reports of patients treated in the stomatology and maxillofacial surgery unit directed by professor Vaillant, Hôpital Salpêtrière, Paris. Findings allowed certain conclusions to be drawn with respect to diagnostic and therapeutic features and to compare these with those reported in the international literature.

Adolescent↗