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Biomedical subjects

F Hummel

Publications and source records attributed to F Hummel.

5 recordsLinked to original sources

[Double blind study on maprotiline, an example of a multidimensional psychopharmacologic experiment (author's transl)].

Antidepressive therapy with maprotiline was accompanied by blood level determinations psychological clinical and electroencephalographical assessments. It was the aim of the study to introduce objective methods in psychotropic drug therapy and to look for a relationship between blood level and clinical outcome, EEG and psychological data. We found a "therapeutical window" of blood levels between 300 to 600 ng/ml of maprotiline (oral dose of 75 or 150 mg per day). There is also a relationship between clinical outcome rated by the Hamilton-Depression-Scale and the d2-cancellation-test.

Administration, Oral

[Multidimensional pharmacopsychiatry in gerontopsychiatry: studies on the therapy with tricyclic antidepressant drugs (author's transl)].

A Concept for the multidimensional assessment and correlation of serum level and outcome of therapy with psychomopharmaca with chemical, psychological, psychophysiological, electroencephalographical and clinical methods is shown. It is possible by this method to correlate clinical outcome to serum level and effect of the drug and to objectivate the efficacy of the pharmacon. Applications in Gerontopsychiatry are discussed.

Aged

Developing outcome assessment methods.

Describing the development of an outcome assessment method for accreditation, the authors discuss development of criterion definitions and the evaluation of results from a pilot study using student portfolios. The subsequent design of an outcome assessment tool to provide concrete, objective data, the evolution of the evaluation process using this tool, and how the outcome data are currently used for curriculum evaluation are discussed.

Accreditation