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Biomedical subjects

F Huth

Publications and source records attributed to F Huth.

At least 37 records · Page 2Linked to original sources
PubMed1979

[Histological and morphometric investigations of knee joint synovial membrane concerning diabetic arthropathy (author's transl)].

Joint capsular tissue from both knee joints have been investigated light microscopically and morphometrically in 40 cases with maturity onset of diabetes. The tissue specimen were taken from autopsy cases (27 female, 13 male). The following alterations of synovial tissue can be regarded as typically in diabetes mellitus: 1. An increased formation of synovial villi without proliferation of synoviocytes and without inflammatory reaction. 2. Increased hyalinosis and fibrosis of the synovial villi as well as fibrosis of the flat synovial membrane. The alterations were far developed in more than 50% of all cases with diabetes.

Aged↗
PubMed1979

[Spontaneous hemorrhages into dilated conjunctival lymphatics (author's transl)].

The means of own observations the clinical picture of spontaneous hemorrhages into the conjunctival lymphatics is illustrated. The reasons of this phenomenon are discussed with regard to the histomorphological findings. Hitherto the spontaneous hemorrhages into the conjunctival lymphatics do not seem to have any pathogenic effect.

Adult↗
PubMed1979

[Morphometric studies on lymphatic vessels of the axillary region].

Axillary lymph vessels of 94 autopsy cases (42 female, 52 male) have been investigated histologically in serial slices. Total diameter of the lymph vessels, vascular wall diameter, diameter of the medial connective tissue, finally that one of the artificial tissue spaces were measured in almost 8000 single measurements. The mean values of counts for the different vascular wall components were assessed statistically with the aid of a computer. By reason of the enormous individual variation of the number and the size in lymph vessel system a direct comparison of the measurement data from the different wall components was impossible. Therefore, the ratio of connective tissue to smooth muscle within the vascular media was regarded as a significant parameter for the development of a lymphangiosclerosis. The connective tissue/smooth muscle gradient increased from decade to decade with a slighter progression in groups with higher age A significant increase of lymphangi osclerosis was noted in cases with right heart insufficiency in correlation to the degree of heart insuffiency. Severe lymphangiosclerotic alterations were developed after radical mastectomy and radiotherapy of the axilla, after radiotherapy of other malignant tumors, and in cases with heart failures or vascular dysplasia. Morphometric investigations were not possible in cases with floride lymphangitis and in one case of general vascular amyloidosis.

Adolescent↗
PubMed1978

Electron microscopic findings in four cases of nasopharyngeal fibroma.

Light and electron microscopic investigations of four cases of juvenile nasopharyngeal fibroma revealed characteristic structures; a fibrous stroma, an inclination to hyalinisation and formation of scar like tissue, a lacunar thin walled vascular component, large numbers of mast cells and of fibroblasts. The tumor fibroblasts contained different nuclear bodies and particles. There existed five different types of more or less complex spherical bodies. The previously described nuclear electron dense particles with an electron lucent halo could be divided into four groups measuring 60, 90, 150, and 300 nm in diameter. In addition to the previously described ultrastructural properties of the tumors, the nuclei of the tumor fibroblasts were found to contain virus like particles. These particles were less electron dense, measuring 40 to 55 nm in diameter and arranged in groups throughout the nucleoplasm; they were different from chromatin condensations and from perichromatin granules. The structure and the size of the smallest particles was not comparable with the other nuclear inclusions.

Adolescent↗
PubMed1978

The synovial changes in post-traumatic synovitis and osteoarthritis.

The histopathologic appearances of post-traumatic synovitis and synovitis of osteoarthritis cover a limited range of changes and have features in common. Electron microscopy yields information complementary to that given by light microscopy. With these techniques, based on sufficient material, histological analysis linked with clinical observation will permit some degree of differentiation between the two conditions.

Adolescent↗
PubMed1978

[A new method of lymphadenography of the regional lymph nodes of the human urinary bladder. Findings relevant to cancer of the bladder (author's transl)].

Experience with and findings of a new method of indirect lymphography (endovesical lymphography) for roentgenologic visualization of lymph nodes and lymphatic vessels of the human urinary bladder are presented. After injection of Lipiodol Ultrafluid into the submucosal layer of the bladder wall all regional lymph node groups could be demonstrated. In cases of carcinoma of the bladder, endovesical lymphography provides early evidence of beginning carcinomatous infiltration of regional lymph nodes. Pedal lymphography as used thus far, provides information only about advanced lymphatic metastatic spread. It is possible that endovesical lymphography will yield new information leading to more accurate treatment of vesical carcinoma in terms of tumor staging.

Humans↗
PubMed1978

[Morphology of nasopharyngeal fibroma (author's transl)].

Light and electron microscopic investigations of four cases with juvenile nasopharyngeal fibroma revealed the characteristic structures like a fibrous stroma, and inclination to hyalinisation and formation of scar like tissue, a lacunar thin walled vascular component, a high amount of mast cells, and of fibroblasts with different nuclear bodies and particles. The well known electron dense nuclear inclusions were subdivided into three groups of size. The tumor cell nuclei also contained five different types of more or less complex bodies with spherical shape. In addition to the earlier described ultrastructural properties of the tumor the nuclei of the tumorous fibroblasts were found to contain virus like particles measuring 40 to 55 nm in diameter. These particles were aggregated to groups; they were different from chromatin condensations and from perichromatin granules. The structure and size of the smaller particles was not comparable to that of the electron dense nuclear inclusions regarded as pathognomonic in the nasopharynegal fibroma.

Adolescent↗
PubMed1977

[Reaction of synovial membranes in knee joint with primary extra-articular systemic diseases (author's transl)].

Postmortal histologic examinations of the synovial membrane of both knee joints were conducted in 85 selected cases. The following conditions were given priority: diabetes mellitus, advanced renal insufficiency, liver cirrhosis with ascites, chronic insufficiency of the right heart, vericose syndrome of the lower extremities, tumours compressing organs of the pelvis minor as well as a few rare infectious and tumerous diseases. Comparison of the histomorphologic findings revealed consistancies such as pronounced ultravillous branching of the synovial membrane with villous hyalinosis in diabetes mellitus, increased, coarse villi formation in renal insufficiency and liver cirrhosis, edema of the synovial membrane in chronic insufficiency of the right heart and renal insufficiency as well as a number of nonspecific reactions of the synovial membrane in obstruction of venous drainage. In the context of generalized fibrotic processes such as in Ormond's disease and scleroderma, similar reactions of the synovial membrane are pronounced. Arthralgic complaints and secondary arthroses in those systemic diseases not primarily involving joints can be at least partially clarified by histomorphologic findings.

Adult↗
PubMed1976

[The effect of antiaggregating agents - acetylsalicylic acid (ASA) and dipyridamol - on the rejection of allotransplanted canine kidneys in presensitized animals (author's transl)].

The effect of antiaggregating agents - acetylsalicyclic acid (ASA) and dipyridamol - on the rejection of allotransplanted canine kidneys in presensitized animals were studied. Blood flow dropped more markedly in the control group than in the group treated with ASA and dipyridamol. 24 hours after transplantation the blood flow in this group was significantly higher than in the control group (p 2,5 %) and in the third group treated with dipyridamol alone. The cellular rejection started earlier and was more pronounced in the control group. Only in this group vascular rejection and microthrombi were demonstrated. Urine output ceased 24 to 60 hours after transplantation. The immunosuppressive, antiphlogistic and platelet antiaggregating effect of the combined ASA and dipyridamol therapy is thought to be responsible for the better results in this group. In this experimental model the combined treatment of ASA and dipyridamol results in a later onset of cellular rejection, in better blood-flow of the kidney and later onset of anuria.

Animals↗
PubMed1976

[Experimental inoculation of Leishmaniasis tropical from man to man (author's transl)].

Experimental transformation of leishmaniasis from man to man was demonstrated. The infection occurs through direct inoculation of the leishmania organism in the amastigote form: from an ulcer of a leishmania papule some materials were obtained and were inoculated intradermally in the thigh of one of the authors. Within weeks a red papule has developed in the place of inoculation from which the microorganisms were frequenctly demonstrated. The papule was cured spontaneously within 70 weeks under a formation of a flat pigmented scar. In the electronenmicroscopy the microorganisms were seen to be located intracellular. The microorganism had a double outer membrane, an oval nucleus, and a kinetoplast out of which (in the phlebotomus fly or in the culture) the future flagellum would be formed.

Humans↗
PubMed1976

[A new method of demonstrating the regional lymph nodes of the urinary bladder (author's transl)].

Pedal lymphography as used up to now does not fully demonstrate the lymphatic drainage of the bladder. A new method is presented in which Lipiodol-Ultra-Fluid is injected into the submucosal layer of the bladder wall under endoscopic vision. In 27 endovesical lymphographies the following lymph nodes could be demonstrated: the anterior, lateral and posterior vesical, the obturator, the external and internal iliac and the common iliac nodes.

Cystoscopy↗
PubMed1976

[Results of gastric lymphography with particular reference to gastric carcinoma (author's transl)].

The regional lymph nodes of the stomach can be visualised radiologically by injecting Lipiodol Ultra-Fluid into the submucous layer of the stomach wall through a gastroscope. Lymphography was performed in gastrologically healthy probands (n = 10), in patients with gastroduodenal ulceration (n = 17), and in patients with gastric carcinoma (n = 35). In 28 of the gastric carcinoma patients the first order lymph nodes were demonstrated, in 21 cases the second order and in 15 cases the third order whereas defects in uptake indicated metastases in 16 patients which could be histologically confirmed in 13. Gastric lymphography may contribute to the indication for operation if metastases are suspected in the second and third order lymph nodes as nodes along the upper border of the pancreas and the coeliac trunk are very difficult to remove radically.

Female↗