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Biomedical subjects

F L Goss

Publications and source records attributed to F L Goss.

At least 37 records · Page 2Linked to original sources
PubMed1996

The effects of acute exercise on gallbladder function in an adult female population.

It has been suggested that aerobic exercise influences gallstone disease pathogenesis through its effects on gallbladder motility. The purpose of the present investigation was to examine the effects of acute aerobic exercise on gallbladder emptying. Gallbladder function was evaluated, via cholescintigraphy, in 12 healthy females after undergoing two experimental trials [i.e., postprandial (P) and exercise + postprandial (E + P))]. In the E + P trial, 60 min after injection of 99mTc disofenin, subjects exercised for 30 min at 65.3 +/- 0.9%, (mean +/- SEM) of VO2 peak on a recumbent leg ergometer, and then ingested 8 oz of a liquid meal to promote gallbladder emptying. In the P trial the meal was administered at the same time relative to the E + P trial; however, for the 30 min prior to meal ingestion subjects remained in a resting supine position. Postprandial gallbladder ejection fraction (EF) was nonsignificantly higher in the E + P trial (49.4 +/- 5.1%) than in the P trial (46.6 +/- 6.7%). Results of this study also indicated that during a fasted state the gallbladder undergoes significant periods of spontaneous emptying both at rest EF = 25 +/- 5.6% (P < 0.02) and during exercise EF = 17 +/- 4.3% (P < 0.01). In conclusion, the results of this study indicate that 30 min of aerobic exercise at 65% of VO2 peak does not effect gallbladder motility in a healthy, premenopausal, female population.

Adult↗
PubMed1996

Effect of exercise intensity on glucose and insulin metabolism in obese individuals and obese NIDDM patients.

OBJECTIVE: The primary purpose of this study was to evaluate the acute effect of exercise of differing intensity on plasma glucose and insulin responses to an oral glucose challenge. RESEARCH DESIGN AND METHODS: Six obese men and six obese men with NIDDM of similar age, weight, percentage body fat, and VO2peak participated in the study. Each subject underwent two 7-day exercise programs in a counterbalanced order at 2-week intervals. During each 7-day exercise period, the subjects cycled every day at a power output corresponding to 50% VO2peak for 70 min or 70% VO2peak for 50 min. Muscle glycogen utilization was estimated during exercise on day 7 using a [3H]glucose infusion technique in conjunction with indirect calorimetry. During the day before and after each 7-day exercise period, a 3-h oral glucose tolerance test (OGTT) was administered after a 12-h overnight fast. RESULTS: The average caloric expenditure did not differ between exercise at 50 and 70% VO2peak in both obese and obese NIDDM subjects. However, the carbohydrate oxidation was higher (P < 0.05) during exercise at 70 than 50% VO2peak in obese subjects (77 +/- 5 vs. 68 +/- 6 g) and obese NIDDM subjects (70 +/- 4 vs. 58 +/- 6 g). Muscle glycogen utilization was also higher (P < 0.05) during exercise at 70 than 50% VO2peak in obese subjects (59 +/- 9 vs. 30 +/- 7 g) and in obese NIDDM subjects (48 +/- 5 vs. 24 +/- 5 g). In obese subjects, plasma glucose response area during the OGTT did not change after 7 days of exercise at either 50 or 70% VO2peak. Plasma insulin response area during the OGTT also did not change after 7 days of exercise at 50% VO2peak. However, plasma insulin response area was reduced (P < 0.05) after 7 days of exercise at 70% VO2peak (9,644 +/- 1,783 vs 7,538 +/- 1,522 microU.ml-1.180 min-1). In obese NIDDM subjects, both plasma glucose and insulin response areas during the OGTT did not decrease after 7 days of exercise at either 50 or 70% VO2peak. CONCLUSIONS: It is concluded that the exercise-induced improvement in insulin sensitivity is influenced by exercise intensity in obese individuals. The improved insulin sensitivity after 7 days of exercise at 70% VO2peak in obese individuals may be related to greater muscle glycogen utilization during exercise. The lack of improvement in glucose tolerance and insulin sensitivity after 7 days of exercise at either 50 or 70% VO2peak in obese NIDDM patients may be due to the fact that the NIDDM patients selected in the present study were relatively hypoinsulinemic.

Adipose Tissue↗
PubMed1996

Effect of carbohydrate substrate availability on ratings of perceived exertion during prolonged exercise of moderate intensity.

This investigation examined the effect of carbohydrate substrate availability on ratings of perceived exertion (RPE) during cycling at moderate intensity to exhaustion and the relation between submaximal endurance performance and RPE obtained following 2 hr. of cycling at moderate intensity. Seven male cyclists performed two exercise trials at power output corresponding to 70% of their peak oxygen uptake until exhaustion. Subjects ingested either a 6% glucose/sucrose solution at the rate of 0.6 g.kg-1 (Body Weight).hr.-1 or an equal volume of artificially flavored placebo every 20 min. throughout the exercise trials. RPE for the legs, chest, and over-all body, and oxygen consumption, expired ventilation, carbohydrate oxidation rate, and blood concentrations of glucose, glycerol, and lactate were measured every 20 min. throughout exercise and at exercise termination. Statistical analysis of these dependent variables indicates that (1) an exercise-induced decrease in blood-borne carbohydrate substrate intensifies leg and over-all perceptions of exertion during the later stages of prolonged cycling at 70% VO2peak. (2) Factors other than availability of blood-borne carbohydrate substrate may influence perceptual intensity at exhaustion. (3) Ratings of perceived exertion for the legs and over-all body obtained after 2 hr. of cycling at moderate intensity may be useful in predicting submaximal endurance performance.

Attitude to Health↗
PubMed1995

Effect of carbohydrate ingestion subsequent to carbohydrate supercompensation on endurance performance.

This investigation determined whether carbohydrate ingestion during prolonged moderate-intensity exercise enhanced endurance performance when the exercise was preceded by carbohydrate supercompensation. Seven male trained cyclists performed two trials at an initial power output corresponding to 71 +/- 1% of their peak oxygen consumption. During the trials, subjects ingested either a 6% glucose/sucrose (C) solution or an equal volume of artificially flavored and sweetened placebo (P) every 20 min throughout exercise. Both C and P were preceded by a 6-day carbohydrate supercompensation procedure in which subjects undertook a depletion-taper exercise sequence in conjunction with a moderate- and high-carbohydrate diet regimen. Statistical analysis of time to exhaustion, plasma glucose concentration, carbohydrate oxidation rate, fat oxidation rate, and plasma glycerol concentration indicated that in spite of a carbohydrate supercompensation procedure administered prior to exercise, carbohydrate ingestion during exercise can exert an additional ergogenic effect by preventing a decline in blood glucose levels and maintaining carbohydrate oxidation during the later stages of moderate-intensity exercise.

Adult↗
PubMed1994

The acute effects of exercise intensity on HDL-C metabolism.

To determine whether exercise intensity influences acute HDL-C responses, 12 male recreational runners (24.8 +/- 4 yr) who ran 15-30 miles.wk-1 exercised on a motor driven treadmill at 60% (L) and 75% (H) VO2max. A counterbalanced experimental design was utilized and energy expenditure was 800 Kcal. Fasting blood samples were obtained 24 h before exercise (24 PRE), immediately post-(IPE), 1 h post- (1 h PE), 6 h post- (6 h PE), and 24 h post- (24 h PE) exercise and analyzed for HDL-C and HDL2&3-C. In addition, postheparin plasma samples, obtained 24 h PRE, 6 h PE, and 24 h PE were analyzed for lipolytic activity--LPLA and HTGLA. An exercise trial by time interaction was observed for HDL-C (P < 0.01). Post-hoc analysis revealed no change in HDL-C following the L trial. However, an increase in HDL-C was observed 24 h PE (P < 0.01) following the H trial. The increase in HDL-C was attributed to an elevated HDL3-C (P < 0.01), with no change in HDL2-C. Analysis of plasma lipolytic activity revealed an increase in LPLA 24 h PE (P < 0.05) which may be responsible for the postexercise alterations in HDL-C. However, HTGLA decreased 6 h PE (P < 0.01) and 24 h PE (P < 0.05). We conclude that increases in HDL-C levels following endurance activity are influenced, in part, by the exercise intensity.

Adult↗
PubMed1993

Effects of body morphology and mass on thermal responses to cold water: revisited.

Seven male volunteers were divided into two groups based on body morphology and mass. The large body mass (LM) group (n = 4) was 21.2 kg heavier and 0.32 m2.kg-1 smaller in surface area-to-mass ratio (P < 0.05) than the small body mass (SM) group (n = 3). Both groups were similar in total body fat and regional skinfold thicknesses. All subjects were immersed to the first thoracic vertebrae for 120 min in stirred water at 18 degrees C. Overall, tissue insulation was similar (P > 0.05) between the SM and LM groups across time. Perceptual ratings of thermal sensation increased (P < 0.05) across time. Therefore, as cold water immersion progressed, tissue insulation was similar and thermal sensation increased (P < 0.05) in males matched for subcutaneous fat and total fat but differing in body mass and morphology.

Analysis of Variance↗
PubMed1993

Effect of repeated exercise bouts on high density lipoprotein-cholesterol and its subfractions HDL2-C and HDL3-C.

Nine sedentary men (mean age, 22.8 yrs) were studied during and after treadmill exercise at 65% VO2max to determine the number of repeated exercise bouts required to bring about a sustained elevation in HDL-cholesterol and its subfraction HDL2-C and HDL3-C. A Latin square counterbalanced design was used. Thirty minute exercise sessions were undertaken in the following patterns: (1) single bout, (2) two bouts on alternate days, and (3) three bouts on alternate days. The exercise bouts in patterns 2 and 3 were separated by 48 h. Patterns 1, 2 and 3 were conducted 7 days apart. Blood samples were obtained prior to each pattern and at 5 min, 24 and 48 h after the last session within each pattern. There were no significant differences in triglycerides and total cholesterol between the selected blood sampling points for all patterns. Total HDL-C remained higher (p < 0.05) than the pre-exercise level 5 min [pattern 1: 39.0 vs 41.2 mg.dl-1, pattern 2: 37.1 vs 39.2 mg.dl-1, pattern 3: 38.8 vs 42.7 mg.dl-1] and 24 h [pattern 1: 39.0 vs 39.4 mg.dl-1, pattern 2: 37.1 vs 39.1 mg.dl-1, pattern 3: 38.8 vs 42.6 mg.dl-1] post-exercise. Total HDL-C declined to pre-exercise values 48 h post-exercise in all patterns. HDL2-C was lower (p < 0.05) than pre-exercise 48 h for all exercise patterns. For all patterns, HDL3-C levels were higher (p < 0.05) at the 5 min and 48 h post-exercise time points than at the pre-exercise.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1993

Amino acid arterial concentration and muscle exchange during submaximal arm and leg exercise: the effect of dihydroxyacetone and pyruvate.

The mixture of dihydroxyacetone and pyruvate (DHAP) is an ergogenic aid that enhances muscle glucose extraction during prolonged aerobic exercise. In order to evaluate the effect of DHAP on muscle amino acid extraction during exercise, we measured arterial concentration and muscle exchange of amino acids in 18 untrained healthy male subjects (aged 20-30 years) performing dynamic arm (60% VO2 max, n = 9) or leg (70% VO2 max, n = 9) exercise to exhaustion with and without dietary supplementation of DHAP. The subjects consumed diets (146 kJ kg body weight-1 day-1) containing either 100 g polyglucose, Polycose (placebo, P) or DHAP (3:1, treatment) substituted for a portion of carbohydrate. The two diets were administered in a double-blind, random, crossover order for a 7-day period. At least 7 days separated the dietary protocols. Blood samples were drawn through radial artery and axillary or femoral vein catheters at rest, during exercise and at exhaustion. Arterial alanine concentration increased by 30% during arm exercise and by 50-60% during leg exercise. No other arterial amino acid concentration changed during exercise. At exhaustion, arterial alanine concentration decreased to pre-exercise levels with arm exercise but remained elevated after leg exercise. Despite changes in arterial concentrations of alanine with exercise, muscle exchange of alanine was not altered with exercise. Exercise did not alter muscle exchange of any amino acid. Arterial amino acid concentrations and muscle exchange of amino acids with exercise were similar with or without DHAP feeding.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1993

Physiological responses to maximal treadmill and handweighted exercise.

The purpose of this investigation was to compare the peak physiological responses among four protocols that employed different amounts of handweighted exercise in 16 males (aged 26.3 +/- 4.1 years). The four protocols were (a) uphill treadmill running (UR; 3.36 m.s-1, 2.5% grade increase-3 min-1); (b) uphill treadmill walking while pumping 1.36-kg handweights (HW) (UWHW; 1.79 m.s-1, 5.0% grade increase x 3 min-1; (c) treadmill walking while pumping .91-kg HW (WHW; 1.79 m.s-1, 0% grade, .91-kg HW increase x 3 min-1); and (d) standing in place and pumping HW (SHW; arm work as described in WHW). It was hypothesized that the peak responses would be inversely proportional to the estimated muscle mass activated (i.e., UR = UWHW > WHW > SHW). Dependent variables included peak oxygen uptake (VO2 peak), peak heart rate (HRpeak), peak ventilation (Ve peak), and peak respiratory exchange ratio (RERpeak). No differences were noted between UR and UWHW with respect to any of the dependent variables. All variables (except RERpeak) were greater (p < .01) in UR and UWHW than either WHW or SHW. RERpeak was greater (p < .01) in UR and UWHW than in WHW. VO2 peak and HRpeak were greater (p < .01) in WHW when compared to SHW. Mean VO2 peak was 97.5, 69.7, and 60% of UR for UWHW, WHW, and SHW, respectively. Therefore, walking and pumping handweights provides a maximal stimulus to the oxygen transport system.

Adult↗
PubMed1993

Are beta-endorphins and thermoregulation during cold-water immersion related?

The purpose of this investigation was to determine the relationship between core temperature (Tre), tissue insulation (I), and beta-endorphins (beta-END) during immersion in cold water. To test this, 21 males were immersed to the first thoracic vertebra for 120 min in stirred water at either 18 degrees, 22 degrees, or 26 degrees C. Subjects were divided with respect to body fat [high fat (HF) = 18-22%, n = 11; low fat (LF) = 8-12%, n = 10] and randomly assigned to one of the three temperatures. Blood was drawn at 25 and 5 min (T-25 and T-5, respectively) before immersion, after 1 h of immersion, and 5 min before the completion of the second hour (T + 60 and T + 120, respectively). No significant relationship was found between delta beta-END and delta I or delta Tre. The relationship between the changes in thermoregulatory variables and delta beta-END did not differ between the HF and LF groups. Also, beta-END (adjusted for plasma volume) was lower (P < 0.05) in the HF vs. the LF group. beta-END (pg.ml-1) increased (P < 0.05) as time increased from T-25 to T + 60 and were not progressive with duration of immersion. Thus, beta-END did not increase in proportion to level of heat loss.

Adult↗
PubMed1992

The validity of regulating exercise intensity by ratings of perceived exertion.

The purpose of this investigation was to examine the regulation of exercise intensity by using Ratings of Perceived Exertion (RPE). The RPE equivalent to 50% and 70% VO2max was estimated by using standard clinical protocols on a treadmill and cycle ergometer. Subjects then produced the target RPEs on these modalities. Physiological validity of perceptually regulated exercise intensity was determined by comparing VO2 and heart rate between estimation and production trials at the same relative intensity. With one exception, RPE was found to be a valid means of regulating exercise intensity both intra- and intermodally at 50% and 70% VO2max. Perceptual regulation of intramodal treadmill exercise was not valid at 70% VO2max in that both VO2 and heart rate were significantly lower during production than estimation. The present results also indicate that target RPE estimated during a cycle ergometer graded exercise test is more accurate for regulating exercise intensity than when the target RPE is estimated during a treadmill test. The lower accuracy found for treadmill production at the higher exercise intensity may have been caused by the use of a test protocol during the estimation trial that included relatively slow speeds and large inclines. In general, RPE provide a physiologically valid method of regulating exercise intensity.

Adolescent↗
PubMed1992

Abatement of exertional perceptions following dynamic exercise: physiological mediators.

Perceptual and physiological congruity was examined during recovery from high-intensity dynamic exercise. Nine males (24.8 +/- 0.6 yr; VO2max; 52.3 +/- 1.5 ml.kg-1.min-1) undertook in random order four maximal treadmill protocols. Treadmill speed was held constant (5.3 km.h-1) while grade was incremented by 2, 4, 6, or 8% every 3 min for protocols A, B, C, and D, respectively. Ratings of perceived exertion (RPErec; Borg 15-point scale), ventilation (VE), respiratory rate (RR), oxygen uptake (VO2), and heart rate (HR) were measured preexercise and during each min of a 12-min supine postexercise period that immediately followed treadmill testing. Ratings were obtained for the peripheral perceptual signal arising from the legs (RPErec-L), the respiratory-metabolic signal from the chest (RPErec-C), and the overall body signal (RPErec-O). Blood pH was measured preexercise and during min 1, 6, and 12 of recovery. RPErec-L and RPErec-O were lower (P less than 0.05) and blood pH higher (p less than 0.05) following protocol A than D at all recovery time points. RPErec-C, VE, and RR were lower (P less than 0.05) for protocol A than D at all recovery time points. Differences among protocols were not noted for VO2 or HR at any recovery time point. The decay in signal strength for both RPErec-L and RPErec-O following high-intensity exercise reflected the abatement of metabolic acidosis. RPErec-O was influenced by the abatement of pulmonary ventilation during the postexercise period.

Acidosis↗
PubMed1991

Physiological and thermal responses of males with varying body compositions during immersion in moderately cold water.

The effect of body composition on the thermal and metabolic responses of 24 male volunteers (20 to 35 years) was examined during 90 min of moderately cold (18, 22, or 26 degrees C) water immersion to the first thoracic vertebrae. Body composition was determined via underwater densitometry. Subjects were divided with respect to body fat (high fat (HF) = 18-22%, n = 12; Low fat (LF) = 8-12%, n = 12) and randomly assigned to one of three water temperatures. Rectal temperature (degree C) after 90 min of immersion did not differ in LF and HF at 18 degrees C (35.9 vs. 36.2), 22 degrees C (36.0 vs. 36.0), and 26 degrees C (36.0 vs. 36.3). Oxygen uptake (VO2, ml-kg-1.min-1) was greater in LF than in HF in all water temperatures. Oxygen uptake at 90 min was greater for LF than HF in 18 degrees C (11.48 vs. 9.19), 22 degrees C (9.79 vs. 4.70), and 26 degrees C (6.21 vs. 5.44). Mean skin temperature in LF and HF approached water temperature within the first 5 min. Despite the thermal strain of cold water immersion, the LF subjects were able to maintain a similar Tre compared to the HF due to a significantly greater shivering thermogenesis.

Adipose Tissue↗
PubMed1990

Blood glucose extraction as a mediator of perceived exertion during prolonged exercise.

The effect of blood glucose extraction on the perception of exertion was examined during prolonged arm exercise. Eight male subjects consumed in counter-balanced order a standard daily diet containing either (1) 75 g dihydroxyacetone and 25 g sodium pyruvate (DHAP) or (2) an isocaloric amount of placebo, to manipulate blood glucose extraction. Following each 7-day diet, subjects exercised to exhaustion at 60% of peak arm oxygen consumption. Ratings of perceived exertion (Borg, CR-10 scale) were obtained for the arms (RPE-A), legs (RPE-L), chest (RPE-C) and overall body (RPE-O) every 10 min of exercise. After 60 min of continuous exercise, blood samples were drawn from the radial artery and axillary vein. Ratings of perceived exertion did not differ between trials during the first 50 min of exercise. At the 60-min time point, perceived exertion was lower (P less than 0.01) in the DHAP than placebo trials for the arms (RPE-A: 4.25 vs 5.50) and overall body (RPE-O: 3.25 vs 4.00). These differences persisted throughout exercise. RPE-L and RPE-C did not differ between trials. Whole-arm arterial-venous glucose difference was higher (P less than 0.05) in the DHAP (1.00 mmol.l-1) than placebo (0.36 mmol.l-1) trials, as was fractional extraction of glucose (22.5 vs 9.0%). Respiratory exchange ratio was the same between trials. Triceps muscle glycogen was (1) higher in the DHAP than placebo trial at pre-exercise (P less than 0.05), (2) decreased during exercise and (3) did not differ between trials at exercise termination.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1990

Enhancement of arm exercise endurance capacity with dihydroxyacetone and pyruvate.

The effects of dietary supplementation of dihydroxyacetone and pyruvate (DHAP) on endurance capacity and metabolic responses during arm exercise were determined in 10 untrained males (20-26 yr). Subjects performed arm ergometer exercise (60% peak O2 consumption) to exhaustion after consumption of standard diets (55% carbohydrate, 15% protein, 30% fat; 35 kcal/kg) containing either 100 g of Polycose (placebo, P) or DHAP (3:1, treatment) substituted for a portion of carbohydrate. The two diets were administered in a random order, and each was consumed for a 7-day period. Biopsy of the triceps muscle was obtained immediately before and after exercise. Blood samples were drawn through radial artery and axillary vein catheters at rest, after 60 min of exercise, and at exercise termination. Arm endurance was 133 +/- 20 min after P and 160 +/- 22 min after DHAP (P less than 0.01). Triceps glycogen at rest was 88 +/- 8 (P) and 130 +/- 19 mmol/kg (DHAP) (P less than 0.05). Whole arm arteriovenous glucose difference (mmol/l) was greater (P less than 0.05) for DHAP than P at rest (0.60 +/- 0.12 vs. 0.05 +/- 0.09) and after 60 min of exercise (1.00 +/- 0.12 vs. 0.36 +/- 0.11), but it did not differ at exhaustion. Neither respiratory exchange ratio nor respiratory quotient differed between trials at rest, after 60 min of exercise, or at exhaustion. Plasma free fatty acid, glycerol, beta-hydroxybutyrate, catecholamines, and insulin were similar during rest and exercise for both diets. Feeding DHAP for 7 days increased arm muscle glucose extraction before and during exercise, thereby enhancing submaximal arm endurance capacity.

Adult↗
PubMed1990

Enhanced leg exercise endurance with a high-carbohydrate diet and dihydroxyacetone and pyruvate.

The effects of dietary supplementation of dihydroxyacetone and pyruvate (DHAP) on metabolic responses and endurance capacity during leg exercise were determined in eight untrained males (20-30 yr). During the 7 days before exercise, a high-carbohydrate diet was consumed (70% carbohydrate, 18% protein, 12% fat; 35 kcal/kg body weight). One hundred grams of either Polycose (placebo) or dihydroxyacetone and pyruvate (treatment, 3:1) were substituted for a portion of carbohydrate. Dietary conditions were randomized, and subjects consumed each diet separated by 7-14 days. After each diet, cycle ergometer exercise (70% of peak oxygen consumption) was performed to exhaustion. Biopsy of the vastus lateralis muscle was obtained before and after exercise. Blood samples were drawn through radial artery and femoral vein catheters at rest, after 30 min of exercise, and at exercise termination. Leg endurance was 66 +/- 4 and 79 +/- 2 min after placebo and DHAP, respectively (P less than 0.01). Muscle glycogen at rest and exhaustion did not differ between diets. Whole leg arteriovenous glucose difference was greater (P less than 0.05) for DHAP than for placebo at rest (0.36 +/- 0.05 vs. 0.19 +/- 0.07 mM) and after 30 min of exercise (1.06 +/- 0.14 vs. 0.65 +/- 0.10 mM) but did not differ at exhaustion. Plasma free fatty acids, glycerol, and beta-hydroxybutyrate were similar during rest and exercise for both diets. Estimated total glucose oxidation during exercise was 165 +/- 17 and 203 +/- 15 g after placebo and DHAP, respectively (P less than 0.05). It is concluded that feeding of DHAP for 7 days in conjunction with a high carbohydrate diet enhances leg exercise endurance capacity by increasing glucose extraction by muscle.

Adult↗
PubMed1990

Cross-modal exercise prescription at absolute and relative oxygen uptake using perceived exertion.

Cross-modal exercise prescription at absolute and relative oxygen uptake using perceived exertion. Med. Sci. Sports Exerc., Vol. 22, No. 5, pp. 653-659, 1990. The validity of cross-modal prescription of exercise intensity based on rated perceived exertion (RPE) was determined for eight men (26 +/- SE 1.9 yr) at absolute and relative VO2. Exercise modes were treadmill (TM), cycle ergometer (C), and bench stepping while pumping 0.91 kg handweights (HB). Relative (Rel) constant load sessions were performed for each mode at 70% of mode-specific VO2 peak. Absolute (Absol) constant load sessions were performed for C and HB at the VO2 equivalent to 70% of TM VO2 peak. The five 12 min sessions were presented on separate days in random order. RPE-Overall during TM-Rel (11.1) was a) lower (P less than 0.05) than C-Absol (12.6) and HB-Absol (12.5) and b) the same as C-Rel (11.3) and HB-Rel (10.7). RPE-Legs during TM-Rel was a) lower (P less than 0.05) than C-Absol and HB-Absol and b) the same as C-Rel and HB-Rel. RPE-Chest a) did not differ between TM-Rel and C-Absol or HB-Absol and b) was lower (P less than 0.05) for C-Rel and HB-Rel than TM-Rel. RPE-Arms was higher (P less than 0.05) for C-Absol, HB-Absol, and HB-Rel than TM-Rel but did not differ between TM-Rel and C-Rel. Oxygen uptake, heart rate, and ventilation during TM-Rel were a) the same as C-Absol and HB-Absol and b) higher (P less than 0.05) than C-Rel and HB-Rel. Perceptually based cross-modal prescription of exercise intensity using a psychophysical estimation method is valid provided that the physiological reference is the relative, not the absolute, VO2.

Adult↗