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Biomedical subjects

F Michot

Publications and source records attributed to F Michot.

At least 73 records · Page 4Linked to original sources
PubMed1989

[Digestive hemorrhage caused by rupture of esophageal varices. Analysis of 47 emergency surgeries].

Between 1 January 1984 and 31 December 1986, 47 patients out of a total of 228 patients admitted to hospital with endoscopy-proven bleeding esophageal varices, underwent an emergency operation. The indications were massive hemorrhage in 29 patients, and rebleeding early after a first serious episode in 18 patients. Four patients underwent early reoperation for recurrent variceal bleeding. Thirty-seven porto-caval shunts, 10 esophageal transections, 3 proximal gastric resections and 1 exploratory laparotomy were performed. The early results were satisfactory in 53.2% of the patients; operative morbidity and mortality were 19.1% and 27.7% respectively. Four patients died from gastric variceal bleeding soon after esophageal transection. Operative mortality was greater when the patient was Child C or operated for massive hemorrhage. Survivors were followed for at least 12 months. Two patients died from shunt occlusion and recurrent variceal bleeding. No severe encephalopathy was reported. Analysis of the results suggest that porto-caval shunt is indicated in Child A or B patients, particularly with recurrent variceal bleeding soon after a first episode controlled medically.

Adult↗
PubMed1989

[Infrahepatic hematoma secondary to gangrenous cholelithiasic hemocholecyst treated with antivitamins K].

Acute haemocholecyst is a rare disorder but often reported in patients with gallstones. Rupture of the gallbladder causing hypovolaemic shock secondary to massive intraperitoneal bleeding has been reported in about fifty patients to date. We report a new case of haemocholecyst with rupture of the gallbladder in a patient with gallstones treated by anticoagulant therapy. This case is unusual in terms of the nature of the gallbladder disease: massive gangrene with complicating hemorrhage and destruction of deficient regions of the wall of the gallbladder induced an infrahepatic haematoma without hypovolemic shock, in contrast with the massive intraperitoneal hemorrhage reported in other cases.

Aged↗
PubMed1988

[Acute intestinal ischemia from arterial thrombosis. Value of emergency arteriography and revascularization].

A 77 year old woman undergoing surgery for acute digestive arterial thrombosis, was successfully revascularized without intestinal resection. Early diagnosis is difficult and is based upon evaluation of past history and an arteriography when there is the slightest doubt. Apart from when necrosis is already developed, revascularization by aorto-superior mesentric by-pass using an autologus saphenous vein and a routine "second look" to assess intestinal viability is the best therapeutic approach.

Aged↗
PubMed1988

[Isolated aneurysm of the common hepatic artery. Apropos of a case report].

A case is reported of an isolated aneurysm of the common hepatic artery revealed by pain in liver region. The etiology is mainly dominated by atheroma and media dysplasia. Detection is currently during investigation of a pain syndrome or jaundice and no longer after rupture of aneurysm. Ultrasound imaging value is emphasized and angiography provides valuable data. Surgical treatment and particularly the indication for hepatic revascularization are discussed as a function of anamnestic and angiographic arguments and intraoperative findings.

Aneurysm↗
PubMed1987

[Microangiopathic hemolytic anemia, erythrophagocytosis and consumption coagulopathy in vinyl chloride-induced hemangiosarcoma of the spleen and liver].

A case of angiosarcoma of the liver and the spleen following vinyl chloride exposure is described. The main symptoms in clinical diagnosis were microangiopathic hemolysis, disseminated intravascular coagulation, hepatosplenomegaly and exposure to vinyl chloride thirty years ago. It is the first case in which liver and spleen are involved in angiosarcoma due to vinyl chloride exposure. The tumor cells showed angioformative and solid histiocytoid growth with erythrophagocytosis.

Aged↗
PubMed1987

Alcohol-induced bone marrow damage. A bone marrow study in alcohol-dependent individuals.

Bone marrow biopsies from 30 alcohol-dependent individuals hospitalized for detoxification were investigated. Typical alcohol-induced bone marrow changes were found and served to define alcohol-induced bone marrow damage as a nosological entity. The findings took the form of heightened ineffective erythropoiesis associated with impaired iron utilization, vacuolated proerythroblasts, multinuclear erythroblasts, megaloblasts and iron-containing plasma cells as well as vacuolated precursor cells of the granulocytopoietic series. In the differential diagnosis, alcohol-induced bone marrow damage is to be distinguished from the myelodysplastic syndrome of the RA and RARS form. Alcohol-induced bone marrow damage is reversible. Bone marrow cell cultures performed in our cases are normal, showing that the toxic defect probably does not reside in the stem cell but is more peripheral. Normal bone marrow cell culture may be a typical feature of alcohol-induced bone marrow damage.

Adolescent↗
PubMed1984

[Diagnosis of alcoholism in repeatedly intoxicated motorists. A study of 100 evaluations].

A total of 100 persons who had been repeatedly convicted of drunken driving were submitted to assessment by a medical expert. A series of uniform criteria were used to determine whether they suffered from alcoholism. The following methods of investigation were used: 1. a conversation relating to drinking habits, psychosocial background and sociological circumstances; 2. the MALT (Munich alcoholism test); 3. physical examination; 4. laboratory tests. Using these methods it was possible to distribute those examined into one of the following groups (according to WHO and Jellinek): non-alcoholics (10%), problem drinkers (49%) and addicted drinkers (41%). These three large groups presented a typical picture in respect of age, occupational group, blood alcohol concentration/journey, MALT index, pathological findings at physical examination and abnormally raised laboratory values. In particular, the triad of MCV, gamma-GT and macrocytosis played an important role in aiding the recognition of alcoholism or alcohol dependence. The additional presence of a raised value for SGPT further supported the diagnosis. In 37% of cases, regular alcoholic intake began during basic military service and in 28% at the place of work (mostly on building sites). In both of these groups it would appear important to institute appropriate preventive measures.

Alcoholic Intoxication↗
PubMed1984

[A case of iatrogenic mercury incorporation caused by balloon rupture of a Miller-Abbot tube in intestinal subileus].

A young man admitted with diagnosis of subileus was treated as usual by Miller-Abbot catheter with a mercury-filled balloon at the distal tip. During treatment of this patient the mercury-filled balloon ruptured, but no signs of poisoning occurred despite a blood mercury level 4 times higher than normal. In contrast to one fatal case described in the literature, the present case followed a course without signs of mercury intoxication under treatment with Dimaval (Na-2,3,-dimercapto-1-sulfanat).

Adult↗
PubMed1984

Multiple myeloma occurring in association with a preexisting neuromuscular disease (progressive muscular dystrophy). A chance occurrence or a nosological entity?

This paper describes 3 patients with progressive limb-girdle muscular dystrophy who many years after this disorder was diagnosed were found to have a monoclonal gammopathy. The authors examine whether this was a fortuitous occurrence together of two rare disorders or whether they might be causally related. So far no other similar cases have been reported in the literature.

Action Potentials↗