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Biomedical subjects

F Mosimann

Publications and source records attributed to F Mosimann.

At least 145 records · Page 8Linked to original sources
PubMed1983

Long-term follow-up after a distal splenorenal shunt procedure. A clinical and hemodynamic study.

Of 26 patients who underwent distal splenorenal shunting 4 or more years ago (1969 to 1978), 10 died 3 to 87 months postoperatively (mean 38.5 months). Six deaths were due to liver failure, two to hemorrhagic peptic ulcer disease (the shunt remained patent in each patient), one to brain hemorrhage, and one to sepsis. Eight of the surviving patients resumed professional activity, one showed transient signs of encephalopathy, one had a single episode of recurrent variceal bleeding that could be managed conservatively, and no patient had ascites. Eight patients were investigated angiographically and endoscopically. Preoperative and postoperative measurements of the portal vein showed a decreased diameter in five patients and no opacification in the other three 29 to 97 months after surgery. At endoscopy four patients had small residual esophageal varices, one patient had none, and the other three had large varicosities with variceal pressures between 30 and 40 cm H2O in two and above 40 cm H2O in one. Although the incidence of postoperative encephalopathy and variceal bleeding was low after distal splenorenal shunting, the operation did not prevent a decrease in hepatopetal portal flow and did not always abolish the esophageal varices.

Adult↗
PubMed1982

Endoscopic noninvasive manometry of esophageal varices: prognostic significance.

Our study attempts to establish a relation between the pressure in the esophageal varices and the clinical outcome in 18 patients in whom sclerotherapy for bleeding esophageal varices was performed. The measured pressure was compared to the endoscopic findings. Before sclerotherapy, a noninvasive manometric measurement was performed on the varices using a spheric membrane manometer fixed at the tip of an endoscope. Twelve of our 18 patients suffered repeated hemorrhage which led to death in five. We discovered a relation between the measured pressure and the outcome. Beside this, we measured the highest pressures in the largest varices. The relation that seems to exist between the pressure in the esophageal varices, the endoscopic findings, and the severity of the portal hypertension may provide new opportunities for research in this field.

Adolescent↗
PubMed1982

Strain gauge plethysmographic studies after clipping of the inferior vena cava.

Assessment of the hemodynamic effects of the IVC clipping by strain gauge plethysmography provides accurate quantitative data. These correlate very well with the other means of investigation used in the study. Eight patients were controlled in the Vascular Laboratory 9 to 43 months after clipping of the inferior vena cava. They submitted to clinical evaluation, Doppler ultrasound, isotopic venography, abdominal sonography, and strain gauge plethysmography of the lower extremities. This last method provided quantitative data; maximal venous outflow was found to be equivalent in the 8 patients included in the study and in a control group of 20 healthy young volunteers. Strain gauge plethysmography results correlate well with the other means of investigation and demonstrate the efficacy of the dilated venous collateral channels in restoring a normal venous return.

Abdomen↗
PubMed1981

Intraluminal jejunal diverticulum.

An intraluminal diverticulum of the jejunum in a 19-year-old man is reported. A congenital diaphragm was bypassed by jejunojejunostomy when the patient was 2 days old. A "ballooning" mechanism of this diaphragm can explain the pathogenesis of the diverticulum.

Adult↗
PubMed1980

[Transplantation of the islands of Langerhans: evaluation and perspectives].

Islets of Langerhans transplantation was studied in four groups of dogs (autotransplantation after immediate or delayed total pancreatectomy; allotransplantation with immediate total pancreatectomy or 4 days after total pancreatectomy). It is concluded: 1. that it is unnecessary to separate endocrine from exocrine pancreatic elements; 2. that a moderate hyperglycemia for a few days after transplantation is required for ultimate survival and function of transplanted material; 3. that further experimental work has to be done before allotransplantation can be safely performed in man.

Animals↗
PubMed1980

Is alveolar hydatid disease of the liver incurable?

The etiologic agent of alveolar hydatid disease is Echinococcus multilocularis. Infestation of the liver by the larvae of this Cestode results in an infiltrative mass that behaves biologically very much like a malignant tumor. From 1955 to 1978, 13 patients with alveolar hydatid disease of the liver were investigated, operated and followed at the University Medical Center of Lausanne, Switzerland. Due to the extension of the lesions, six patients had exploratory laparotomy with biopsy only; the other seven were submitted to hepatic resection. Follow-up demonstrated that the disease progresses slowly and that a resection, even if incomplete, can afford long-lasting relief. However the present data suggest that surgical cure of alveolar hydatid disease must be very rare.

Adult↗
PubMed1980

[Obturator hernia, an equivocal diagnosis].

Three cases of obturator hernia are reported. An association of small bowel obstruction and obturator neuralgia in an elderly woman is strongly suggestive of the diagnosis. Anatomy, etiology and treatment are briefly discussed.

Age Factors↗
PubMed1980

[9 cases of portal hypertension of rare etiology].

Nine cases of portal hypertension of unusual etiology are presented: 1 with retroperitoneal fibrosis, 2 with alveolar hydatid disease, 3 with arterio-portal fistula, 2 with primary biliary cirrhosis and 1 with sarcoidosis.

Aged↗