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Biomedical subjects

F Nöthiger

Publications and source records attributed to F Nöthiger.

At least 37 records · Page 2Linked to original sources
PubMed1980

[Stercoraceous perforation of the colon (author's transl)].

Stercoraceous perforation of the colon is mainly observed in patients with chronic renal failure. Pathophysiology and clinical feature is demonstrated on the basis of the experience with 10 patients. Prophylaxis of stercoraceous formations is important, for after the perforation prognosis is very poor: only 1 patient survived. Surgical therapy consists of resection of the whole involved colon with out primary anastomosis.

Aluminum Hydroxide↗
PubMed1980

[Experience with 50 clinical manifestations of small intestine tumors].

During the last 20 years we have seen 50 tumors of the small bowel, of which 28 were malignant. The low 5-year survival rate of 33.8% was due to a high operative mortality because of an advanced stage of the disease with ensuing complications such as perforation. In 50% of all obstructive tumors, associated peptic ulcerative lesions have been observed in the stomach or duodenum probably induced by stasis in the upper bowel. Therefore, the small bowel should always be inspected carefully during operation for peptic ulcer which did not heal with conservative treatment.

Humans↗
PubMed1980

[Operative procedure guidelines for the treatment of colonic volvulus].

In Western Europe volvulus of colon is a very rare disease. We observed only 15 cases within 15 years among more than 70,000 patients. In comparison with the literature we try to give some recommendations for the treatment of colonic volvulus. If the intestine is without disturbance of blood supply a two stage proceeding is proposed: first derotation of the intestinal loop and in a second step elective resection. If there is gangrene or perforation incontinuity resection without primary anastomosis is recommended.

Colonic Diseases↗
PubMed1979

[Colorectal cancer].

Incidence of colorectal cancer is increasing during the last years. 5% of the population get affected. From these a group of patients with a higher carcinoma risk must be separated: that with adenomas, familial polyposis and ulcerative colitis. Nourishment seems to be one of the main factors for the development of cancer. Although all important principles of radical surgery are realized, this 5-year survival rate for colorectal cancer is less than 40%. Prophylaxis, early diagnosis and the effect of irradiation and drug therapy must improve the relatively poor prognosis of colorectal cancer, which has reached in Germany the highest mortality and even -- with the exception of skin cancer -- the highest morbidity of all malignant neoplastic diseases.

Colonic Neoplasms↗
PubMed1979

[Morphological and biochemical examinations of different suture materials in colon anastomosis in the rat].

Histological, mechanical and biochemical examinations in the one layer colon anastomosis of the rat have shown that the synthetic resorbable suture material as Dexon and Vicryl are as good or even better than silk or catgut chromic. The most favourable histological reaction is observed with Dexon. Collagenolytic activity and collagen content are not influenced by the suture material during the first 14 postoperative days.

Alkaline Phosphatase↗
PubMed1978

[Tumor surgery: principles of radical treatment (author's transl)].

The 5-year survival rate for curative radical resections of colorectal cancer including Dukes' stages A-C has not improved during the last 20 years. The main principles of surgical treatment have now been realized: en-bloc resection of the tumor together with its lymph drainage system, primary high ligature of the supplying blood vessels, prophylaxis of peroperative metastases and a high total resection rate with low operative mortality. In the future, an improved prognosis must come from prophylaxis, early diagnosis, and improved methods of irradiation and chemotherapy, because the limits of surgical treatment have been reached.

Colectomy↗
PubMed1978

[Spontaneous colon perforation in patients with chronic kidney failure].

Although spontaneous colonic perforation is a rare event, if has recently been observed with increasing frequency in patients with renal failure. Several of the drugs given to such patients may induce dehydration of faeces; the combination of very hard faecal masses and an abnormal fragility of the uraemic intestinal mucosa will then lead to the formation of a decubital ulcer. Prophylaxis or at least early diagnosis are imperative because after completed perforation the prognosis is very poor. The operative method of choice is the incontinuous resection of the entire segment of the colon affected by faecal impaction.

Adult↗
PubMed1978

[Methods of local excision of rectal neoplasms].

Recent experience in the behaviour of rectal carcinomas allows local tumour excision under certain conditions to be carried out as a "total excision-biopsy in healthy tissue". The indication for operation depends on criteria referring to the tumour as well as to the patient. The operation technique is that of transanal excision. Brief survey of personal results.

Humans↗
PubMed1977

[Amebiasis as surgical emergency].

Report of 2 cases of systemic complications many years after inappercept infection with amoeba histolytica. Amoebiasis being a rare affection in Switzerland, diagnosis was missed and not revealed till operation. One case with multiple liver abscesses, healed after drainage and chemotherapy with metronidazol and dehydroemetine. In the other case with colonic perforation and multiple liver abscesses combined surgical and drug therapy failed, the patient died in hepatotoxic coma. Short cut of clinics and therapy in amoebiasis, pointing out that surgery is reserved for the complications as great liver abscess, colonic perforation or fistula between abdominal and pleural cavity.

Dysentery, Amebic↗