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Biomedical subjects

F Nissim

Publications and source records attributed to F Nissim.

33 records · Page 2Linked to original sources

Subcutaneous fat necrosis of the newborn.

A case of subcutaneous fat necrosis of the newborn is described. Severe perinatal asphyxia preceded the appearance of the skin lesions. Premature rupture of membranes and the presence of foul-smelling meconium raised the possibility of infection by anaerobes as an additional etiologic factor. The main hypotheses concerning the cause and pathogenesis of this condition are reviewed. The alarming clinical picture that stands in sharp contrast to the benign prognosis is stressed.

Adipose Tissue↗

Tuberculoid cornstarch granulomas with caseous necrosis. A diagnostic challenge.

We studied a patient in whom peritoneal granulomas developed with caseous-type necrosis after exposure to cornstarch from surgical gloves. This necrotizing type of lesion, which is the least common among cornstarch granulomas, can simulate tuberculous infection and lead to initiation of antituberculous therapy. A review of the literature suggests that there are two basic types of cornstarch granulomas: the phagocytic, foreign body type, and the tuberculoid granuloma with and without central necrosis. The morphologic features and possible mechanism of formation of these types of granulomas are being discussed. Although the cornstarch particles can be identified with a variety of stains, the most reliable method is that of examination with polarized light, which is recommended in all cases of granulomas, especially abdominal ones.

Diagnosis, Differential↗

Skin petechiae and ecchymoses (vasculitis) due to anticoagulant therapy.

The appearance of petechiae and ecchymoses following anticoagulant and fibrinolytic therapy is an unusual and rare complication. The mechanism of the vasculitis is obscure but may be related to a chemical vasotoxic reaction. During anticoagulant and fibrinolytic therapy, 6 patients developed petechiae and ecchymoses which was accompanied by pain and fever. There were no disturbances of blood clotting factors. In spite of the varied action of the different anticoagulants and fibrinolytic drugs, the clinical course and the histological examination demonstrated a similar identical vasculitis.

Aged↗

Granulomatous reaction in lymph nodes draining laryngeal carcinoma.

Presented are two cases of simultaneous occurrence of epithelioid granulomas and metastatic squamous cell carcinoma in cervical lymph nodes draining supraglottic carcinoma. Laboratory tests and radiological and clinical findings ruled out sarcoidosis, as well as mycotic, mycobacterial, or other bacterial infection. Upon finding of epithelioid granulomas in cervical lymph nodes, a malignant tumor of the head and neck region should be considered as a differential diagnostic possibility. Uncritical acceptance of a diagnosis based solely on the histological appearance may lead to erroneous treatment.

Carcinoma, Squamous Cell↗

Ovarian malignancies in pregnancies complicated by colonic perforation.

Primary or secondary ovarian carcinoma in pregnancy is very rare. The entity is difficult to diagnose and is not infrequently fatal. Two unusual cases of ovarian carcinoma during pregnancy, complicated by perforation of the colon, are described. Treatment depends upon the time of diagnosis, the stage of growth, and possible complications. More attention should be paid to complaints concerning bowel function during pregnancy, and pelvic sonography and bowel studies may enable earlier diagnosis.

Adenocarcinoma↗