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F Nobbe

Publications and source records attributed to F Nobbe.

52 records · Page 3Linked to original sources
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Local longtime lysis in combination with percutaneous transluminal angioplasty (TPA).

In order to produce an endogenous lysis in case of local longtime lysis Urokinase is infused directly into the occlusion in a maximum dosage of 40,000 U/h via an arterial catheter. Remaining stenoses are extended by means of a dilatation catheter. The so far obtained results concerning 72 patients with very long and/or very old arterial occlusions show a primary success-rate of 96% and a 2 years' patency rate of 85% for all patients with a primary success of treatment. Complications and side-effects are scarce with this method. Therefore it can be applied with patients for whom other recanalising catheter methods are not indicated and with whom vascular surgery is not possible. However, a lasting success of treatment is only to be expected on the basis of the precise planning and careful performance of a long-term after treatment.

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[Significance of geriatric polypathy for conservative diagnosis and therapy of arterial occlusive disease in advanced age].

The kind of diagnostic procedures and treatment required in patients with arterial occlusive diseases in advanced age depends on the high risk of multimorbidity. Drug-interactions must be controlled in the multimedication of risk factors in atherosclerosis and of concomitant internal diseases. Intermittent claudication in older patients can also be treated successfully by physical training; in the late stages hemodilution and angioplasty are efficient modern procedures of treatment.

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