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Biomedical subjects

F Piscioli

Publications and source records attributed to F Piscioli.

72 records · Page 4Linked to original sources
PubMedDate not supplied

Uselessness of thermography for diagnosis and follow-up of cutaneous malignant melanoma.

Thermography is useless for diagnosis of cutaneous malignant melanomas (CMM). In fact, false negative thermograms (29.9%) are much more numerous than clinically suspicious cases. Thermography is useless for follow-up of CMM. False-negative and false-positive thermograms of metastatic lymph nodes, subcutaneous nodules and removal site of CMM are much too numerous.

Follow-Up Studies↗
PubMedDate not supplied

Role of percutaneous pelvic node aspiration cytology in the management of bladder carcinoma.

Six of the 23 patients with bladder carcinoma who underwent percutaneous pelvic node aspiration biopsy cytology for staging purposes showed positive findings from nodal chains. Pelvic lymphadenectomy revealed no false-positive or false-negative cytologic results. The fine needle aspiration of opacified pelvic nodes under fluoroscopic control is of great diagnostic value, with a high accuracy in detecting nodal extension of bladder carcinoma and providing a rational basis for proper therapy. Positive aspiration results may be accepted as a basis for therapeutic decisions. Since the metastatic involvement of multiple nodes makes any therapeutic treatment as well as cystectomy completely useless, positive aspirations from more than two nodes may spare patients an unnecessary radical surgery.

Aged↗
PubMedDate not supplied

Urinary cytology of tuberculosis of the bladder.

The cytologic findings in the urinary sediment of 13 patients with tuberculosis (TB) of the bladder were compared with the histologic findings. TB was cytologically recognized in 11 patients because of the presence of epithelioid and/or Langhans' giant cells. The morphologic deviations of the urothelial cells and the urothelium were classified according to the criteria of Koss. The type I atypical urothelial cells found in ten patients were correlated to the urothelial hyperplasia found at histology; the follow-up data documented the benign reversible nature of the urothelial hyperplasia as the focal expression of the reactive potential of urothelium to various forms of inflammatory processes. The presence of type II atypical urothelial cells reflected moderate and severe atypia of the urothelium at biopsy. In order to assess the reactive, reversible or precancerous nature of these forms of atypia associated with TB, an accurate follow-up is necessary. Since TB of the bladder may cause the presence of atypical cells in the urine, this lesion is of special interest in the differential diagnosis between inflammatory processes and carcinoma.

Adult↗
PubMedDate not supplied

Fine needle aspiration biopsy in the evaluation of lymphoreticular tumors of the thorax.

The role of fine needle aspiration (FNA) biopsy in the evaluation of lymphoreticular disorders involving the lung and mediastinum was evaluated in a study of 16 cases from the authors' institutions. The cytologic material from these cases was reviewed, and the original cytologic interpretations were compared to the tissue diagnoses, with the overall accuracy of the cytologic interpretation evaluated. There were no false-positive diagnoses of malignancy in this series. A definite diagnosis of malignant lymphoma was most readily made in those cases in which the lymphoma was of the large-cell type. Small-cell and mixed large-cell and small-cell lymphoid proliferations were less able to be definitively interpreted, with pseudolymphoma presenting particular difficulty. The results support the conclusion that FNA biopsy can be useful in evaluating these lesions but also emphasize the fact that accurate diagnosis requires correlation of cytologic, clinical and laboratory data.

Aged↗
PubMedDate not supplied

Cytologic presentation of renal adenocarcinoma in urinary sediment.

The role of cytology in 44 cases of renal adenocarcinoma was evaluated. The diagnosis of neoplasia was made with radiographic means in all cases; urinary cytology was positive in only 19 patients (43.18%) and is therefore considered unsatisfactory in the detection of renal adenocarcinoma. The cytologic presentation of this disease was characterized by four different malignant cellular types. Multinucleated cells with distinct nucleoli as well as large vacuolated cells with hyperchromatic, eccentric nuclei showed the same cellular morphology seen in the corresponding histologic pictures. Granular eosinophilic cells, with pyknotic nuclei and distinct and/or ill-defined cytoplasmic borders, are believed to be the result of degenerative changes caused by the urinary environment. The multinucleated cell type was almost benign in appearance and could be confused with benign urothelial cells. The malignancy and the renal origin of such cells were confirmed by the observation of strikingly similar cells in the parent neoplasms.

Adenocarcinoma↗
PubMedDate not supplied

Primary malignant melanoma of the esophagus. Brush cytology and histogenesis.

The cytologic findings in a case of malignant melanoma of the esophagus in a 57-year-old male are described. Fiberoptic endoscopy showed a large brown mass in the lower tract of the esophagus and a strongly pigmented epithelium around the tumor. Brush cytology showed malignant melanoma cells with Fontana-Masson-positive granules and typical intranuclear vacuoles. The surgical specimen revealed a malignant melanoma of the esophagus, with the surrounding epithelium characterized by junctional changes and the presence of benign melanocytes in the basal layer. The latter finding is the only sure criterion for proving the primary nature of malignant melanoma of the esophagus.

Cytodiagnosis↗
PubMedDate not supplied

Pseudomalignant cytologic presentation of spermatic hydrocele fluid.

An unusual cytologic presentation of spermatic hydrocele fluid is reported. The aspirate contained highly atypical cells, exhibiting marked anisocytosis and nuclear abnormalities strongly suggestive of cancer. On histologic examination the lesion displayed pseudosarcomatous fasciitis in the cyst wall and foci of atypical reactive mesothelial hyperplasia in the lining. This case illustrates a potential pitfall in the cytology of spermatic hydrocele fluid.

Cell Nucleus↗
PubMedDate not supplied

[Physiopathology and therapy of foreign bodies in the upper digestive tract].

Fibroendoscopy is the treatment of choice for foreign oesophageal and gastric bodies. Whereas the presence of objects in the oesophagus demands immediate endoscopic removal, gastric localization does not require any emergency treatment except for cases of perforation or incarceration, as most foreign bodies (80-90%) are eliminated naturally. Only two weeks after ingestion, in the case of failed expulsion, is it necessary to proceed to endoscopic removal so as to prevent decubitus or perforation erosions. Endoscopic extraction is made difficult by the length and weight of the object, on by its smallness and lack of texture, which make it hard to get hold of. In the case of suture stitches, it may be hard to cut them because of the presence of a gastric mucosa reactive granulomatous inflammatory process. Contraindications to endoscopic extraction are the failure of the patient to cooperate, acute oesophagitis (peptic and due to caustics) and perforating in the stomach, due to congenital or acquired malformations, means that surgery is necessary. The elimination of foreign bodies depends on the correlation between shape and size of object and the anatomo-functional components of the digestive ways. With reference to an approximate geometric schematization of transit organs, the physiopathology of foreign bodies may be expressed by means of mathematical formulae whose manifold variables sometimes make the natural elimination of the bodies unpredictable.

Adolescent↗