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F Pizzetti

Publications and source records attributed to F Pizzetti.

32 records · Page 2Linked to original sources
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The effect of heart rate on the slope and pressure half-time of the Doppler regurgitant velocity curve in aortic insufficiency.

The effect of the heart rate on the Doppler aortic regurgitant velocity curve was evaluated in 14 patients with aortic regurgitation. The heart rate was increased in two steps with either endocardial or transesophageal pacing in 12 patients and with atropine sulfate in 2 patients (increased from 66 +/- 7 to 82 +/- 4 beats per minute [step 1] to 100 beats per minute [step 2]) in all patients. The increased heart rate resulted in an increased regurgitant slope (from 3.3 +/- 1.2 to 4.5 +/- 1.7 m/s2 [step 1] to 5.8 +/- 1.9 m/s2 [step 2]; p < 0.01) and a shortened pressure half-time (PHT) (from 442 +/- 136 to 323 +/- 98 ms [step 1] to 254 +/- 69 ms [step 2]; p < 0.01). Such variations occurred in the presence of a prevalent hemodynamic improvement, noninvasively suggested by a decreased Doppler-derived left ventricular end-diastolic pressure (LVEDP) (from 23 +/- 10 to 14 +/- 10 mmHg at the highest heart rate; p < 0.05) and by an increased peak aortoventricular diastolic gradient (from 80 +/- 20 to 84 +/- 22 at the highest heart rate; p < 0.05). The PHT and slope correlated with diastolic time (r = 0.74 and -0.65, respectively; p < 0.001). The relative-PHT (PHT/diastolic time x 100) showed insignificant changes during the increase in heart rate and correlated better than the PTH with color Doppler assessment of regurgitation severity (r = -0.73; p = 0.003, and r = -0.53; p = 0.05, respectively). We concluded that the slope and PHT of the aortic regurgitant velocity curve were rate-dependent; the relative-PHT appeared to limit the influence of the heart rate on PHT.

Adult↗
PubMedDate not supplied

[Study of the retroperitoneal lymphatic spread of müllerian ovarian carcinoma, using lymphography].

From January 1973 to May 1974, 117 patients with ovarian carcinomas were evaluated with lymphography. The tumors were staged and classified histopathologically according to FIGO (1971). Considering all cases, lymphography showed nodal metastases in 44 patients (38%). Lymphography was positive in 36% of serous cystoadenocarcinomas, in 26% of mucinous cystoadenocarcinomas, in 15% of endometrioid carcinomas and in 36% of unclassified carcinomas. Of the 10 cases not identified by cell type, lymphography was positive in 40% of cases. In 68% of cases bilateral involvement was found. The site of metastatic nodes was in 32% of cases only in the iliac chains were both involved. Considering the single node chains we found 36% of para-aortic, 27% of common iliac, 35% of external iliac and 2% of inguinal involvement. Metastases were observed, regardless of histological type, in 25% of cases in stage III, 62% iin stage IV, 54% in recurrences and only in 5% of cases in stage I. Therefore the lymphatic spread seems to occur in more advanced stages and in recurrences. In 28 of 117 patients node biopsy was performed. Histological-lymphographic correlation was correct in 7/7 positive cases and in 19/21 negative cases (93%). These results show that lymphography is a reliable tool in the evaluation of ovarian cancer.

Adenocarcinoma↗