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Biomedical subjects

F Pradines

Publications and source records attributed to F Pradines.

6 recordsLinked to original sources

[The Octopus G1 program. Description and use].

The Octopus global analysis Program G1 was developed as a glaucoma program. It is the combination in a single program of: examination procedures, visual field assessment methods. The whole examination is carried out in three phases: the first phase measures 59 test locations in the central 30 degrees field. All locations are measured with the normal strategy. The local threshold is precisely determined to +/- 1 dB by the proven bracketing method. At the end of the first phase, the system automatically calculates the key values (visual field indices) for mean defect and loss variance. the second phase, which retests the same central field, starts from the threshold values measured during phase one. The additional indices corrected loss variance and short term fluctuation, are calculated. in the last phase 14 selected peripheral points between 30 and 60 degrees excentricity with particular emphasis on the superior and inferior nasal step are determined in a qualitative test. Visual field changes can be detected and categorized in three major groups: (Flammer and coll., 1985). 1. local defects or scotomas in varying depths and sizes. 2. diffused depression of the whole field. 3. Increased short-term. The original index called Corrected Loss Variance could determine an early defect before the existence of a light scotoma. Particularly, an increased Corrected Loss Variance indicates that the deviations are due to real scotomas and not just to scattering effects. The therapeutic decision could be more rational.

Diagnosis, Computer-Assisted

[Computer management of the data of automated perimetry using Octopus 2000 R].

Current perimetry involves automated, static and punctual procedures, which permit the examiner to obtain a numerical value of the sensibility concerning the points tested. Besides its precision and its reliability, perimetry can be used in data processing management due to the characteristic of easy duplication of the examinations. We use a micro-computer which is seperate from the Octopus 2000 R (Apple IIc) and the disc (OmnisII) to process the files. The study is composed of the following areas: the storage and the data processing of patient files, the transformation of numerical data a graphics display, the study of the percentage of loss of surface according to the decibel of sensibility. The data processing of files improves storage according to the criteria defined by the examiner and helps avoid inconvienent research. The graphic transformation of numerical data into isopteres of chosen sensibility improves the definition of the zones of intermediate sensibility. The calculations of the percentage of loss of surface according to the decibel of sensibility allows the appreciation of the size of defects based on depth and quantification. It is also easy to make the comparison between the two fields.

Aphakia, Postcataract

[Statistical analysis of visual fields by the automatic perimeter Octopus 2000 R with the Delta program].

The difference tables gives, on a numeric table, the difference between first and second examination. The confidence interval is given out by a statistical test (T-test) which can be applied to the following parts of visual field: pathological area, whole field. We present a number of visual field examinations (Program 33) from glaucomatous patients, analysed through "change mode". We can make the following remarks: When we assess an improvement, it is underlined in "Delta Program", which indicates: significant improvement. When the visual field is unchanged, "Delta Program" indicates a fluctuation: aggravation or improvement (almost always insignificant). A subjective alteration is always underlined by "Delta Program". The program allows an objective interpretation and, when it is combined with the usual objective interpretation, makes the evaluation of campimetric deficiency easier. The importance of statistical analysis, besides the fact that it associates the visual field to one or several mean values, is to set it off as exactly as possible. Flammer and coll. (1985) propose a new index: "corrected loss variation".

Computers

[Automated and semiautomated perimetry. Comparative trial of 3 devices (Baylor programmer, Friedmann Mark II campimeter, Octopus 2000 R.)].

Modern perimetry involves automated or semi-automated procedures, this computer assisted perimetry (CAP) providing results independent of the examiner, and with marked discrimination of light sensibility through quantification of points tested. A wide variety of CAP devices are available, and a comparative study was conducted in 50 patients using 3 perimetric apparatuses with similar supraliminal static techniques but with variable automated potentials: The Goldman perimeter modified by "Baylor visual fields programmer": static technique for the middle area and kinetic for the peripheral area. The Friedmann Mark II Visual Fields Analyser with a multiple stimulus static technique for the middle area. The Fankhauser Octopus 2000 R perimeter with a precise static technique for middle and peripheral areas. This perimeter, highly automated, also allows statistical evaluation of defects changes, owing to storage of results on magnetic discs. Patients studied had either: glaucoma (25 cases) or neuro-ophthalmologic and retinal disorders (24 cases). Conclusions drawn from the experience acquired by the authors during more than one year of use of the 3 devices were: Rate of detection of defects is excellent with the Octopus and quite good with the Friedmann MKII, but limited in the middle area. The Baylor program does not allow quantification of defects. The image is clear with the Octopus as far as the gray scale is concerned, and more exact as far as the comparative tables are concerned; is not clear with the Friedmann MKII; is typical and clear with the Baylor. The length of examination (which varies with the programs used as far as the Octopus is concerned, and with the patient's reaction time) is usually long with the Octopus and the Friedmann, but short with the Baylor. Time and energy can be gained by the use of the Octopus, since it supplies data obtained from use of the Baylor program associated with that of the Friedmann MKII. The authors prefer to follow up campimetric evolution of glaucomatous patients with the Octopus because it offers more sensibility and precision in quantifying losses. The application of the statistical evaluation delta program on the 2000 R device, which will soon be tested in the Ophthalmological Department, could in an objective way indicate whether there is stabilization or a real progression of glaucomatous defects.

Adenoma