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Biomedical subjects

F Reisecker

Publications and source records attributed to F Reisecker.

At least 55 records · Page 3Linked to original sources
PubMed1987

[Pathogenesis and therapy of nontraumatic compressive radial nerve paralyses--report of an unusual case].

A case of nontraumatic radial nerve palsy at the level of the canalis spiralis is reported. Aetiologically a variation of branching of this nerve combined with an inflammatory swelling is discussed. After the surgical treatment a satisfactory recovery of motor function was seen. The necessity for a careful and thorough examination is demonstrated to diagnose or localise such non-traumatic lesions.

Adult↗
PubMed1987

[Value of early acoustic and somatosensory evoked potentials in monitoring and prognostic assessment of coma in barbiturate therapy--comparison with clinical aspects and EEG].

25 comatose patients suffering from severe cerebral lesions of different etiology were examined during barbiturate-therapy by Glasgow-Pittsburg-Coma-Scoring-System (GPCS), EEG, somatosensory and brainstem acoustic evoked potentials. The findings were correlated in view of prognostic prediction and importance for monitoring. A modified form of the Glasgow-Outcome-Score (GOS; independent-survival, dependent-survival, dead) was used for evaluating the outcome. In case of an initial GPCS less than 10 points none of the patients survived, in case of GPCS greater than 10 points 11 out of 19 patients survived. The latter relation of survival was also found in patients with improving or impairing scores during the observation period. In case of initial burst-suppression pattern in the EEG 7 out of 11 patients survived, in case of diffuse abnormalities with or with-out additional focal signs - 4 out of 10 patients survived, but in the latter there was none with an outcome of independent survival. All patients with an isoelectric EEG died. In case of bilateral recording of scalp- SEP 7 out of 11 patients survived, in case of unilateral loss of scalp-EP 4 out of 8 patients survived, but in the latter cases none with an outcome of independence. All patients with initial bilateral failure of scalp-SSEP or loss during the observation period died. In case of bilateral registrable BAEP (wave I to V) 11 out of 17 patients survived. All patients with initial uni- or bilateral failure of those potentials or loss during the observation period died.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1986

[Value of multimodal evoked potentials in the diagnosis of multiple sclerosis].

94 Patients diagnosed as having multiple sclerosis (MS) were examined by multimodal evoked potentials. According to the criteria of Bauer and Poser the patients were classified as possible, probable and certain forms of MS. Abnormalities were found in the VEP in 82.6% of cases (possible - 44.4%, probable - 87.5%, certain - 95.2%), in the BAEP in 51.3% of cases (possible - 27.3%, probable - 46.2%, certain - 68.8%) and in the SSEP in 71.1% of cases (possible - 35.3%, probable - 67.7%, certain - 88.1%). Subclinical lesions were detected by VEP in 37.0% of cases, by BAEP in 43.6% and by SSEP in 21.1%. Reclassification according to the results of the evoked potentials studies was required in 21.2% of cases. The value of evoked potentials in the diagnosis of MS is discussed with regard to the different forms of evoked potentials, as well as in comparison with other examination techniques.

Adolescent↗
PubMed1986

Carpal tunnel syndrome: neurographical parameters in different stages of median nerve compression.

In a series of 47 cases and 55 hands operated upon for carpal tunnel syndrome, the pre-operative electrodiagnostic findings have been compared retrospectively with the morphological findings within the carpal tunnel during operation. As a main result there was no significant correlation between the degree of electrophysiological changes and the degree of median nerve compression. Only the lack of any motor or sensory response seems to indicate a more severe median nerve compression. In about 20% of cases with operatively proven marked median nerve compression, both distal motor latency and motor nerve conduction velocity were well within normal limits and would not have led to the diagnosis of a carpal tunnel syndrome in these cases. The diagnosis, therefore, cannot be made on the basis of electrodiagnostic pathological values only of distal motor latency and motor nerve conduction velocity, but has to take into account as well the sensory nerve conduction velocity as well as the clinical picture and neurological findings.

Adult↗
PubMed1986

Somatosensory evoked potentials (SSEPs) in various groups of cerebro-vascular ischaemic disease.

Fifty-eight patients suffering from cerebrovascular ischaemic diseases were examined by means of somatosensory evoked potentials (SSEPs). The early components during the first 50 msec were evaluated (N13, P15, N20, P28, CCT = N13-N20). The patients were divided into 4 groups according to the affected vascular region and the reversibility of the symptoms. Reversible ischaemic attacks in the vertebro-basilar artery region: 16 patients. Reversible ischaemic attacks in the internal carotid artery region: 14 patients. Non-reversible ischaemic deficits in the internal carotid artery region: 16 patients. Diffuse vascular encephalopathy: 12 patients. The two groups suffering from reversible ischaemic attacks did not show any significant SSEP differences, either when the right and left sides were compared, or when the groups were compared to a control group. Patients with non-reversible ischaemic deficits of the carotid artery system showed a significant difference of the N20-P28 amplitude compared to controls; it was increased on the non-affected side. The latencies of N20 and CCT showed a significant increase on the affected side; P15 components revealed significant delays on both sides. In patients with diffuse vascular encephalopathy significant delays of N13 and P15 were found on both sides, whereas the CCT was unaffected on both sides. The results are discussed in view of the topologic aspects and reversibility of symptoms.

Cerebrovascular Disorders↗
PubMed1986

Heterogeneity of hereditary motor and sensory neuropathy type I (HMSN I): electroneurographical findings, visual evoked potentials and blood group markers in a family with Charcot-Marie-Tooth disease (CMT).

21 members of a large kinship with autosomal dominant CMT showing typical clinical findings were studied electroneurographically, with visual evoked potentials (VEP) and with blood group markers. In clinically affected members, the mean motor nerve conduction velocity (NCV) of the median nerve was found to be 17.5 m/s (SD 2.4). Contrary to previous genetic linkage studies in CMT families with comparable slow motor NCV, blood group typing in this family excluded close linkage of HMSN I to Duffy locus, which may indicate the existence of another subgroup in CMT neuropathy. Mean latencies of VEP, in both clinically affected and unaffected members, showed no pathological alterations when compared to normals. There was no correlation between NCV and P 100 latencies, but significant variation of P 100 latencies in families of twin brothers could be demonstrated. As already suggested by other authors, our findings may also indicate heterogeneity in this neuropathy.

Charcot-Marie-Tooth Disease↗
PubMed1986

[Intraoperative somatosensory evoked potentials (SSEP) in surgery of cerebral aneurysms: topographical information].

Out of 114 patients who were operated because of cerebral aneurysms, 16 patients were monitored by means of Somatosensory Evoked Potential (SSEP) during the operation. In 9 of these, successful monitoring was possible during the whole duration of the surgical procedure. In the remaining seven, monitoring was impossible over a long period so that these patients were excluded from the present study. Monitoring of the cerebral functions by means of SSEP provides help in aneurysm surgery as follows: Objective evaluation of the function of the somatosensory system. The induced arterial hypotension--usually done in our department--implies danger for the brain, particularly, if rupture of the aneurysm occurs at the same time. In this case, Somatosensory Evoked Potentials provide the possibility to detect lesions of somatosensory neurons at different levels. This makes prognostic conclusions possible. Pathological changes of some SSEP components during temporary occlusion of arteries of the Circle of Willis indicate developing lesions of brain structures. Intraoperative SSEP data were correlated with the postoperative course in all 9 patients. Prognostic conclusions derived from these data are discussed.

Adult↗
PubMed1986

[Heterogeneity of neural muscular atrophies].

Classification of the hereditary motor and sensory neuropathies is discussed and findings reported in the recent literature are compared to our own findings in a kinship with autosomal dominant CMT. Previous studies in CMT-families with comparable slow nerve conduction velocities had shown positive linkage of this hereditary neuropathy to the Duffy blood group locus; however, blood group typing in the recently studied kinship excluded close linkage, which may indicate the existence of another sub-group in this entity. Testing of visually evoked potentials in this kindred demonstrated significant differences in P 100 latencies of the families of twin brothers. This intrafamilial difference may also be an expression of heterogeneity.

Charcot-Marie-Tooth Disease↗
PubMed1985

[Transient global amnesia].

The clinical picture of transient global amnesia (TGA) is discussed on the basis of the clinical findings in 19 patients. The central symptom is an acute memory loss, leading to disorientation, helplessness and pseudo-confusion. The symptoms last for several hours and then fade away. Pathogenetically a functional impairment of the limbic system is proposed. Most cases of TGA are due to ischaemic disease; rare causes are epileptic seizures, tumours, encephalitis and toxic or metabolic conditions. In order to clarify the aetiology and initiate appropriate therapy meticulous neurological investigation is necessary. The spontaneous prognosis of ischaemic forms is favourable, whilst in other cases it depends on the primary condition.

Adult↗
PubMed1985

[Involvement of the optic nerve in neural muscular atrophy].

Visual evoked potentials (VEP) were investigated in 12 members of a family with Charcot-Marie-Tooth disease, 7 of whom showed manifest clinical signs of the disease. The mean value of the latency P100 of VEP in the 12 patients did not differ significantly from the value in normal controls, nor did the values in members with considerably reduced nerve conduction velocities differ significantly from those in members with normal nerve conduction velocity. Among the investigated members of the family, however, there was a significant difference in mean P100 latency between family H.G. with no clinical signs of the disease and the family of the twin brother, F.G. with clear clinical and neurographic signs of HMSN I. The divergent opinions given in the literature may be explained by heterogeneity, as well as an extreme expression of the inherited defect and a combination of two independently inherited diseases.

Adolescent↗
PubMed1985

[Results of surgical treatment of common peripheral nerve lesions of the upper extremities].

The results of operative treatment and clinical as well as electrodiagnostic findings are discussed in 68 cases. In about one half of our cases a carpal tunnel syndrome was found with excellent outcome of the operation in 93,6%, with fairly good outcome in the rest of the cases. In 14 of the patients studied a sulcus nervi ulnaris syndrome was seen, 9 of them showing excellent improvement after operative neurolysis was performed. Motor function improved in 8 out of 11 traumatic nerve dissections; Restitutio ad integrum was seen in incomplete lesions of the brachial plexus only, useful recovery of motor and sensory functions in 7 out of 10 patients with total plexus lesions. Regarding these good results of operative treatment of mechanical lesions of the peripheral nerves an exact clinical and neurophysiological examination has to be done for diagnosing and localizing those peripheral nerve affections.

Adult↗
PubMed1985

[Somatosensory evoked potentials in comatose patients: comparison with clinical findings, EEG and prognosis].

21 comatose patients were examined by somatosensory evoked potentials (SSEP). The findings were correlated with the stage of brainstem herniation, the EEG and the outcome. We evaluated the early components of the SSEP (N10, N13, N14, P15, N20) in view of presence, latency and interpeak-latency of the potentials. In most cases the percentage of abnormal SSEP increased from caudal to rostral registration sites, but the potential P15 and N20 were equally abnormal. The progression of herniation correlated with increasing abnormality of the potentials. SSEP over the scalp (P15, N20) could not be registered in patients without any EEG-activity (isoelectric). Mean values of latencies and the interpeak-latencies were significantly prolonged in all cases with fatal outcome. Our findings suggest SSEP as a useful tool in the evaluation of brain-dysfunction in comatose patients.

Adult↗
PubMed1985

[Temporary bypass in carotid surgery; peroperative study of various metabolic parameters and the EEG].

Out of a whole of patients of nearly 1000 reconstructive operations of the extracranial carotid artery, which were carried out by a systematic application of the intraluminal shunt, 32 selected patients with extracranial stenosis of the internal carotid artery were examined intraoperatively as to the following parameters of the internal carotid artery and the internal jugular vein: pH, pCO2, pO2, B.E. and the lactate were determined as well. Statistic analysis shows a significant increase of the arteriovenous difference of the lactate from the first to the second and from the first to the third sample.

Brain↗
PubMed1984

[Etiology of cerebral infarcts caused by emboli--subacute bacterial endocarditis].

Bacterial endocarditis is a rare cause of brain infarction. Prediposing factors are frequently valvular defects secondary to rheumatic conditions. A slowly progressive course and atypical symptoms of the disease can mask the condition to such an extent that the correct diagnosis is obtained only through the work up of secondary embolic complications. Modern antibiotic combinations therapy yields a cure in 98% of the cases. The problems obtaining the diagnosis and the course of the disease with antibiotic therapy will be demonstrated in a case of embolic brain infarction secondary to bacterial endocarditis.

Adult↗
PubMed1984

[Somatosensory evoked potential in general anesthesia].

Somatosensory evoked potentials (SSEP) were investigated under general anaesthesia in 12 patients with no history of previous cerebral disease. With the commonly-used stimulation of the median nerve on the wrist, conduction from the homolateral Erb's point, and contralateral conduction from the mastoid and sensory cortical area, SSEP were registered during the first 100 msec. after the stimulation. Latency period, shape and amplitude of the spinal and subcortical components and early cortical potentials (N 20, P 28) show no change, whereas the consecutive negative and positive cortical SSEP show a definite change in shape and latency period. No change was registered in somatosensory impulse conduction and early cortical response under general anaesthesia and these can, therefore, be used during neurosurgery as a parameter for the control of cortical and subcortical functioning.

Adult↗