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Biomedical subjects

F Tedeschi

Publications and source records attributed to F Tedeschi.

44 records · Page 3Linked to original sources

Palatal "myoclonus" and inferior olive hypertrophy with one-sided cerebellar lesion. Clinico-pathological report of one patient.

A case of palatal myoclonus and inferior olive hypertrophy is reported. Lesions located other than in the medulla were cerebellar infarction, lymphomatous infiltrates and, supratentorially, progressive multifocal leukoencephalopathy. It is suggested that double innervation of the olives from either side dentate nucleus may be why in the case reported here and in several cases in the literature, one-sided supra-olivary lesions can produce bilateral hypertrophy. As with palatal "myoclonus" and olivary hypertrophy, it is proposed that if the characteristic rhythmical movements occur, lesions besides those along the dentate-olivary pathway and the olivary hypertrophy itself have to be present.

Cerebellum↗

Skeletal muscle and peripheral nerve changes caused by chronic arterial insufficiency--significance and clinical correlations--histological, histochemical and ultrastructural study.

A histological, histochemical and ultrastructural study on muscle changes in chronic arterial insufficiency has been carried out in 40 patients. Muscle biopsy probes were taken in each patient either from the gastrocnemius or rectus femoris. In 7 patients submitted for amputation of a lower limb due to a more severe vascular disease, specimens were also obtained from both the sciatic and sural nerve for light and electron microscopic study. Our findings confirm the previous histological, histochemical and ultrastructural data on chronic ischemia of the skeletal muscle, suggesting that muscle damage is mainly based on a neurogenic noxa initiated by an ischemic peripheral neuropathy. In addition, many morphologic features also show the presence of a primary myopathic noxa, possibly depending on the direct damage of the mitochondrial respiratory chain by the deficit of the muscle blood supply.

Adult↗

Cytology of giant-cell glioblastoma.

A case is presented in which smears and touch imprints of a parietal tumor in a 58-year-old female revealed two distinct and easily recognizable cellular populations. The first was predominant and consisted of densely packed cells of an astroglial nature. The other was made up of unusually large giant cells with highly malignant features. The cytology of these combined cell types allowed the correct diagnosis of giant-cell glioblastoma at the time of surgery. Their cytomorphology, which has seldom been reported, supported the interpretation of an astroglial nature of this tumor.

Cell Transformation, Neoplastic↗

The squash-smear technique in the diagnosis of spinal cord neurinomas. Report of three cases.

The squash-smear technique was used instead of frozen sections for the rapid intraoperative diagnosis of three neurinomas of the thoracic spinal cord. Characteristic cytologic features that could be considered of diagnostic value were the absence of recognizable cytoplasmic outlines, the elongated, sometimes-wavy appearance of the nuclei and the dense fibrillary background. Nuclear palisades with formation of Verocay bodies were present in one case; these were also identified in the paraffin-embedded permanent sections. Histologically, the tumors were predominantly Antoni type A neurinomas.

Adult↗