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F W Ahnefeld

Publications and source records attributed to F W Ahnefeld.

At least 199 records · Page 11Linked to original sources

[Studies on the glucocorticoid control of zinc metabolism].

In the present paper a possible connection between ACTH stress, cortisol release and serum zinc level is studied. It could be shown that under ACTH stress the reaction of cortisol release is physiological, whereas the zinc level in serum decreases significantly. These reactions recur under insulin stress in a weaker form. On the basis of these results a possible connection between stress situations and hypozincemia was discussed. At the same time a possible misinterpretation with regard to a general zinc deficiency under the condition of a reduced serum zinc level in stress situations is pointed out. In accordance with other authors it can, however, be said that the zinc metabolism probably depends on glucocorticoidal controls.

Adrenocorticotropic Hormone↗

[Studies on the behavior of chromium in serum and urine in polytraumatized patients as well as on the chromium concentration of various infusion solutions].

Determinations of the oligoelement chromium were carried out by flameless atomic absorption spectroscopy in serum, whole blood, and urine of patients, undergoing intensive care, as well as in a great part of the solutions used for parenteral nutrition. With rising amino acid and protein content, respectively, the chromium content of the infusion solutions increased due to contamination. Pure nonglucose-carbohydrate-electrolyte solutions contained 16.5-49.0 mug chromium/litre, amino acid-carbohydrate solutions 36.5-105.0 mug chromium/litre and human albumin solutions, depending on concentration, 86.9-394.2 mug chromium/litre. The average chromium concentration in the patients' serum was 11.3 +/- 0.26 mug/litre, which is twenty times more than the normal values determined by this method, and increased from 8.3 to 16.4 mug/litre within the first seven days. The urinary chromium concentrations were 37.7 +/- 4.1 mug/litre, being three times higher than the average serum values, but remained constant from day to day. The approximate chromium administration by parenteral infusion therapy was 160-250 mug chromium/day, the urinary chromium excretion was 111 +/- 20.5 mug/day. Consequently, great amounts of parenterally supplied chromium seem to be stored in the patients' tissues. Effects and risks for the organism caused by these unphysiological chromium concentrations are discussed.

Accidents, Traffic↗