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Biomedical subjects

G Benea

Publications and source records attributed to G Benea.

At least 19 recordsLinked to original sources

Radiofrequency ablation of liver malignancies: MRI for evaluation of response.

The aim of this study was to investigate the role of magnetic resonance imaging (MRI) in the evaluation of response to radiofrequency ablation (RFA) and detect residual or recurrent tumor. After RFA, the target lesion shows a hyperintensive signal without increased T1-weighted, low on T2-weighted, non enhancing in gadolinium-enhanced MRI. In the long term follow-up the successfully treated lesions decrease in size. Signs of recurrence include new enhancement areas, the lesion's size increase, and development of T1-weighted hypointense and T2 weighted hyperintense areas. The MRI is a reliable method to evaluate the effectiveness of RFA and detect residual tumor.

Catheter Ablation↗

[Video-assisted atypical resection of peripheral lung nodules localized using CT-guided wires. First clinical experiences].

One of the reasons for the rapidly expanding use of thoracoscopic surgery as an alternative to thoracotomy, is the excision of peripheral lung nodules. Nodules judged too small or too far from the pleural surface to be seen during thoracoscopy, must be localized beforehand. The aim of this study was to evaluate the feasibility and effectiveness of percutaneous placement of needle hook-wires to locate such nodules before surgery. Under Ct guidance 5 nodules were pre-operatively identified in 4 patients. The thoracoscopic resection of the lesions was done without complication, in 1 patient the operation had to be converted into an open one to dislodge of the wire. CT-guided hook-wire localization is easily and safely performed and permits thoracoscopic resection of lung nodules, which otherwise might be impossible.

Aged↗

Primary leiomyosarcoma of the aorta: report of a case and review of the literature.

Leiomyosarcoma of vascular origin is an extremely rare lesion especially when it occurs in the arteries. In the present study, we report a case of such a neoplasm, originating in the wall of the descending aorta and give an ample review of world references on the subjects of primary aortic neoplasm. Wright classified aortic tumors into two categories concerning the site of origin in the aortic wall: the first involves the intima, the second group consists of tumors arising in the media or adventitia. The aspecific clinical findings that characterize these lesions explain the difficulty of a preoperative diagnosis. Very important, therefore, are sonography and CT which point out signs and symptoms which refer to a local and distal diffusion of the tumor. However, even in the cases in which the diagnosis is done before surgery, there is no codified therapeutic management. In fact both surgical and non-surgical methods (radiotherapy, chemotherapy) have poor results with an average survival. Due to the limited prognosis "quoad vitam", the elective therapy must preferably be of conservative type.

Aged↗

[Computerized tomography follow-up after percutaneous renal lithotripsy].

Even though extracorporeal shock wave lithotripsy (ESWL) is nowadays considered the treatment of choice for the majority of upper urinary tract calculi, percutaneous stone removal will continue to be an alternative treatment method in selected cases. Therefore, percutaneous techniques must not be forgotten by the interventional radiologist. In order to assess the effects and the potential damage caused by this interventional procedure to kidney and perirenal tissues, CT was performed on 20 patients before and after percutaneous nephrolithotripsy. In the cases where no complications occurred during the maneuver, post-nephrolithotripsy scans demonstrated low incidence of significant renal abnormalities. Thickening of pararenal fascia (8 patients) and irregular renal outline (10 patients) were our most frequent findings. In 5 patients we found edema of the pyelo-ureteral junction, in 3 thickening of the bridging perinephric septa and retained stone fragments, in 2 perirenal hematomas, in one a subcapsular fluid collection. Urinoma with pelvic laceration was demonstrated in the only patient in whom the maneuver presented marked technical problems. On the basis of this series of pre- and post-nephrolithotripsy CT scans of treated kidneys, the authors conclude that this percutaneous technique is quite atraumatic.

Adult↗

[Isthmic coarctation of the aorta. Description of an anomalous case].

An anomalous (because of the advanced age of its onset) case of isthmic coarctation of the aorta in preductal site observed at the persistence of hypertensive symptomatology associated with cephalgic and lipothymic attacks is reported. Instrumental examinations confirmed the clinical suspicion and resective-reconstructive surgical treatment led to complete resolution of both cause and effect.

Adult↗

[Postoperative biliary calculosis: our experience with therapeutic strategy].

The Authors report their experience in the treatment of 92 cases of post-surgical biliary tract stones: 17 early cases (18.5%) were treated by percutaneous nonsurgical extraction (10 cases) or by operative procedures (7 cases); 75 late cases (81.5%) were surgically treated. The Authors summarize the results of the treatment, discussing advantages and disadvantages of the various techniques.

Cholangiography↗

[Advantages of a light-equipped angiographic guide in percutaneous obliteration of the spermatic veins].

Percutaneous transvenous treatment has become the elective therapy for varicocele because it is a simple, safe, economic and reliable procedure. The presence of proximal anastomoses connecting a competent valved spermatic trunk with the renal vein can be responsible for a varicocele and make its treatment difficult. In such cases; the valve of the spermatic venous trunk can be bypassed using an open-ended guidewire with a removable mandril core, and then injecting the sclerosing agent through the guide. Moreover, the guidewire can facilitate the insertion of the catheter through the competent valve, thus allowing the placement of Gianturco coils. During the past 12 months we have successfully treated 4 patients affected by varicocele with competent valved venous trunk using the open-ended guidewire.

Embolization, Therapeutic↗

[Percutaneous subtotal splenic embolization in thalassemia major. A 4-year follow up].

Ten young patients affected with thalassemia major with hypersplenism were treated with subtotal percutaneous embolization. Percutaneous procedure was used to correct hypersplenism, while preserving a small portion of splenic parenchyma. Embolization was successful in 9 patients, and no significant complications were observed; in 1 patient arterial catheterization and splenic embolization were not possible due to splenic artery tortuosity. Post-procedural clinical course was characterized by intense pain, not always reduced by therapy. Hospitalization time was similar to that of surgical splenectomy. Effectiveness of percutaneous embolization was evaluated with splenic scintigraphy, clearance of erythrocytes marked with 99mTc and denatured with BMHP and with the analysis, both before and after percutaneous procedure, of the following 3 parameters: annual blood consumption, behavior of pre-transfusional hemoglobin, and transfusional pause. Six patients underwent a 4-year follow-up. In all cases scintigraphy showed the effectiveness of subtotal embolization, and clearance of erythrocytes appeared slower than before. As for clinics, an improvement was observed in transfusional parameters. The results from our series, though numerically limited, support the role of percutaneous splenic embolization as an alternative to surgical splenectomy in high risk patients or in patients who refuse surgery.

Adolescent↗

[Percutaneous therapy of primary varicocele. 6 years' experience].

Idiopathic varicocele is nowadays accepted as a "social disease" for both its high incidence among young men and its affecting male fertility. Screening is thus required for young people and, above all, early and definitive treatment. We have evaluated the effectiveness of percutaneous sclerotherapy, which has become a standard procedure, in spite of its recent introduction in interventional radiology. One hundred and thirty-nine percutaneous occlusions were performed on 147 patients with varicocele using a sclerosing agent--polidocanol--and stainless steel coils. The failure rate of percutaneous treatment was about 12%. Complications never required hospitalization or surgery; recurrence rate is 3.66%. The patients were followed 3, 6, 12 and 24 months by US and Doppler to survey recurrences, and sperm analysis to estimate the clinical results of percutaneous therapy in infertile patients. Statistical analysis with linear regression of data from spermiograms showed constant improvement in sperm count, sperm motility percentage, and sperm morphology percentage. Fertility index improvement was similar to that of surgical ligation. The radiation dose received by the patient is negligible. Percutaneous therapy represent thus the treatment of choice in case of varicocele: compared with surgery, it offers similar clinical results and a lower recurrence rate, and it can be performed on an outpatient basis. Surgery should be performed only when anatomic variants make percutaneous treatment not feasible.

Adolescent↗

[Percutaneous nephrostomy. A 5-year experience].

The authors report their experience with percutaneous nephrostomy in the treatment of acute renal failure due to ureteral obstruction. One hundred and forty-three patients were treated with the positioning of 218 percutaneous nephrostomy catheters under fluoroscopic guidance. If performed as soon as possible, this percutaneous diversion provides a rapid improvement in renal function and allows an accurate staging of the lesion, as well as correct therapeutic indications. In many cases of urinary obstruction interventional radiology procedures represent a valid and successful alternative to more invasive palliative surgery.

Acute Kidney Injury↗

[Personnel exposure in intraoperative biliary radiology].

The diffusion of percutaneous procedures under fluoroscopic guidance has raised the question of excessive radiation exposure to the patient and to the interventional radiology personnel. In order to give an answer to this question we prospectively evaluated the radiation doses received by the operator's hands, lens, thyroid, and gonads during 243 percutaneous cholangiographies and transhepatic biliary drainages. The absorbed dose was measured with calibrated lithium fluoride thermoluminescent dosimeters applied to the skin (hands, neck, forehead, and gonads). The range of absorbed doses to the four areas was: from 0.013 to 0.219 mGy for the hands, from 0.011 to 0.027 mGy for the thyroid, from 0.007 to 0.019 mGy for the lens; the gonads dose was not measurable due to the dosimeter being placed behind the lead apron. The radiation dose employed during our biliary interventional procedures is higher than that of selective visceral angiography, but lower than that of PTA. On the basis of our data, a radiologist could perform about 2777 PTCs, or 1718 percutaneous biliary drainages, per annum, without exceeding the ICRP dose limits.

Bile↗

[Selective arteriography in fractures of the femur head].

The choice between conservative and radical operation in case of femoral neck fractures is very important because it is the determining factor for a successful therapy. In case of epiphysial necrosis, an endoprosthesis as well as an osteosynthesis will be carried out. Selective arteriography of the medial circumflex artery represents the most reliable study to establish, immediately after the fracture, the possible presence of a post-traumatic ischemic necrosis. Angiography, as a reliable diagnostic tool, has to be carried out in the most selective way and needs the image subtraction technique. The authors report their preliminary results on the reliability of angiography in the femoral epiphyseal ischemic necrosis diagnosed by comparing the results of angiography with the Wood light test carried out on the surgically removed femoral head.

Adult↗

[Culture studies of the bile during transhepatic cholangiography].

A bacterial examination was carried out on bile taken from 119 patients undergoing transhepatic percutaneous cholangiography (P.T.C.) due to biliary obstruction. Bacteria were found in 36.9% of cases, with greater frequency in cases of benign obstructions (69.6%) than malignant obstructions (27.2%). The extent of obstruction was found to make no difference (stenotic or obstructive). These results therefore confirm that a risk of infectious complications during P.T.C. exist. Susceptibility studies carried out on bile bacteria showed gentamycin to be the most effective antibiotic in the prevention and treatment of infection in these cases.

Adult↗