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Biomedical subjects

G Brecht

Publications and source records attributed to G Brecht.

At least 37 records · Page 2Linked to original sources
PubMed1980

[Experimental skull and cerebral trauma and the early changes in the microangiogram in rabbits (author's transl)].

The second part of this investigation describes seven changes which have been observed in the post-traumatic microangiogram: defects, narrowing, rarefaction, incomplete filling, variations in callibre, "amputation" and bleeding. Reduction in the lumen is due to contraction of vessels in the microcirculation; this can be recognised histologically. Various causative factors are discussed. Bleeding and traumatic aneurysms are interpreted as being the result of direct trauma to the vessels.

Angiography↗
PubMed1980

[Thorotrastosis: survey and CT pattern (author's transl)].

Following a historical survey of the discovery of late damages caused by the contrast medium Thorotrast which was commercially available from 1930 to 1951, the article reports on the possibilities of identifying Thorotrast in the computer tomogram. In a male patient aged 60 years, the size and anatomic dimensions of a hepatocholangiolar carcinoma induced by Thorotrast was determined by computer tomography 35 years after carotid angiography. Over and above this, a 20 times increased pathologic tissue density was measured in parapancreatic lymph nodes, whereas the density of tissue was only slightly increased in the liver and twice the normal value in the spleen. The sclerosing and malignoma-inducing properties of Thorotrast as well as the pathogenesis of late damages by foreign body irritation and chronic internal radiation, are discussed.

Humans↗
PubMed1979

[Value and results of computer tomography in diseases of the pancreas (author's transl)].

In a joint study carried out by the radiological university clinics of Bonn, Hamburg, Cologne, Leuven and Munich, 483 computer tomographs of the pancreas were evaluated. A correct histological diagnosis, or one confirmed at surgery, was obtained in 74.5% of 168 cases; in a further 9% an abnormality was seen in the pancreas or in its immediate vicinity, but was wrongly interpreted. The computer tomographic criteria of inflammatory processes and of tumours of the pancreas are given, and the not uncommon difficulties in distinguishing between these are discussed.

Acute Disease↗
PubMed1979

[Computer tomography in the diagnosis of aortic aneurysms (author's transl)].

The paper describes the diagnosis of ten thoracic, 20 abdominal and three peripheral arterial aneurysms by computer tomography. This permits a definite diagnosis by a non-invasive method, it defines the extent of the aneurysm and the amount of thrombus in the aneurysm; it permits recognition of a leak and is painless and without risk and can be performed rapidly. Morever, computer tomography provides an accurate control of growth of the aneurysm. In some cases a dissection can be recognised. The use of adequate quantities of intravenous contrast medium prevents any possibility of an incorrect diagnosis. The extent and density of the aneurysms, their lumina, clot and wall thickness, as determined by computer tomography are described. The values are compared with the aortic diameters of patients with normal vessels. The advantages of the method, compared with other procedures, are discussed and its role in the diagnosis of aortic and peripheral arterial aneurysms is described.

Aged↗
PubMed1979

[Computer-cardio-tomography in idiopathic hypertrophic subvalvular aortic stenosis--a new contribution to non-invasive diagnosis (author's transl)].

The use of computer tomography as a non-invasive procedure in the diagnosis of idiopathic hypertrophic subvalvular aortic stenosis is described. Seven patients were investigated in whom the diagnosis had been confirmed by echocardiography and laevocardiography with pressure measurements. Details of the method are discussed and computer tomography and echocardiography are compared. The features of greatest differential diagnostic importance relating to asymmetrical septum hypertrophy are discussed.

Cardiomegaly↗
PubMed1979

[Computer tomographic demonstration of lymph node metastases from malignant testicular tumours. A comparison of lymphography and computer tomography (author's transl)].

Lymphography and computer tomography was performed on 64 patients with malignant testicular tumours in order to demonstrate lymph node metastases. In 60 patients it was possible to confirm the findings by surgery. In 43 patients there was agreement between the findings of the computer tomogram and the lymphogram. In 39 of these patients lymph node metastases had been demonstrated, in three there was a false negative and in one a false positive. Amongst the patients in whom there was a descrepancy between the two types of examination, the CT findings were confirmed histologically in twelve, and the lymphographic findings in nine. In 12.5% CT added significant additional information. Accuracy of lymphography was 73% and of computer tomography 80%. Specificity for each examination was 79%.

Adult↗
PubMed1978

[Mitral stenosis on conventional radiographs. II. The relationship between pulmonary venous and arterial hypertension, their haemodynamic parameters and calcified mitral valves (author's transl)].

In the second paper, the relationship between pulmonary venous and arterial hypertension and calcification in the mitral valve is analysed statistically and its patho-physiological significance discussed. In one hundred cases of mitral stenosis the left atrium, as seen on the lateral projection, was always enlarged, but its size was independant of atrial pressure or the pressure gradient across the mitral valve. Apart from pulmonary fibrosis and haemosiderosis, the abnormal findings increased with increasing mean atrial pressure. Pulmonary-arterial mean pressure of more than 30 mmHg was found particularly in the presence of mitral valve calcification (94%). Calcification of the valve is the most important and reliable indicator for evaluating the severity of the stenosis.

Adult↗
PubMed1978

[Plasmacytoma of the stomach (author's transl)].

Over a period of two years, enlarged folds in the gastric antrum were found on several occasions, during barium meals, in a 50-year old patient. On gastroscopy and biopsy, the diagnosis of superficial gastritis was made. Six and a half years later the radiological examination, gastroscopy, and biopsy were repeated with suspicion of a malignant tumour. Following histological examination of the resected specimen, the diagnosis of gastric plasmacytoma was made. The features of this rare contition are described and the literature is reviewed.

Biopsy↗
PubMed1978

[Computer tomographic demonstration of an intramuscular haematoma in haemophilia (author's transl)].

Anatomical localisation of intramuscular haematomas can be achieved more accurately by computer tomography than by clinical examination in conjunction with conventional radiography. Computer tomography is able to demonstrate fresh haematomas before they become diagnosable clinically, and before secondary changes, such as calcification or bone erosions, make them visible on conventional radiographs. In this way the diagnosis is made more certain and the choice between conservative or surgical treatment is simplified. Ther period of treatment with clotting factors can, in some cases, be shortened as a result of serial examinations by computer tomography.

Diagnosis, Differential↗
PubMed1978

[Duodenal stenosis in chronic relapsing pancreatitis (author's transl)].

Duodenal stenosis in chronic relapsing pancreatitis occurs in 20% of our patients. In 21 of our cases, the stenosis was always in the descending portion of the duodenum, and in two-thirds it caused an obstruction. The stenosis is always concentric with destruction of the mucosal pattern, widening of the neighbouring folds, irregular contours, and, possibly, straightening of the medial margin of the duodenum. There may be widening of the duodenal loop and frequently the duodenal loop is dilated. The causes for these appearances vary, but a peri-pancreatitis or duodenitis are most frequent. There is no close relationship with the severity of the pancreatitis. Our findings are compared with the small number of reports to be found in the literature.

Adult↗
PubMed1978

[Behçet's disease and the gastrointestinal tract (author's transl)].

Behçet's disease is characterized by the triad of aphteous stomatitis, genital ulcerations and uveitis. This syndrome is thought to be a systemic disease with various unspecific manifestations, which may arise in other organs as well in a considerable number of cases. More than 50% of all patients do have gastrointestinal symptoms; erosive and ulcerative lesions are found primarily in the jejunum and colon. Case reports are given of 3 patients with Behçet's disease and gastrointestinal involvement; one of these patients died. All patients did have unspecific changes of esophageal motility.

Adrenal Cortex Hormones↗
PubMed1976

[Idiopathic thrombosis of the superior vena cava (author's transl)].

In contrast to secondary occlusion idiopathic thrombosis of the superior vena cava occurs rarely. With a good collateral flow through anatomically preformed venous channels the clinical picture may have an insidious course obscuring diagnosis. Collateral circulation via upper oesophageal varices is commonly overlooked. Anticoagulants should be given to prevent progression. Surgically vein transplants, by-pass operations, and thrombectomy have been tried. Follow-up in 4 patients shows that even without surgical intervention the prognosis is good despite the danger of haemorrhage from the varices.

Adult↗
PubMed1976

[The manifestations of regional enteritis (Crohn's disease) in the stomach and duodenum (author's transl)].

Involvement of the stomach and duodenum is relatively rare, but produces distrinct radiological changes. In the stomach the antrum and pyloric portion are affected most frequently. Simultaneous involvement of the duodenum is common. Typical radiological changes consist of funnelshaped narrowing of the antrum, decreased motility of the wall of the stomach, cobblestone mucosa with flat ulcers, deformity of the pylorus and first part of the duodenum and stenosing lesions of the duodenum. If the gastro-duodenal changes occur together with the typical appearances in the jejunum, ileum and colon, then the diagnosis can be made by radiology alone.

Adolescent↗