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Biomedical subjects

G Broniarczyk-Dyła

Publications and source records attributed to G Broniarczyk-Dyła.

5 recordsLinked to original sources

[Correlations between the properties and effects of clinical therapy using textile material with antipsoriatic action].

The aim of the study was to design a textile material as a carrier for dermatological drugs. Cotton fabric was chosen for experimentation to be a fibrous support for the system. Additional components were a drug carrier in form of synthetic hydrogel impregnation (partially crosslinked poly(acrylic acid) and a bioactive agent dithranol) dispersed within the gel. The rate of release of the drug from the fibrous system was measured in aqueous media and depended on the concentration of dithranol. The structure and physical properties of the material were designed and controlled in order to ensure the optimal contact with the skin. Clinical studies were carried out with psoriatic patients. The results of the treatment with the textile material containing dithranol were presented using a computer optimalization method. In conclusion it was asserted that this type of textile-based medical device is effective and in many respects more convenient and less troublesome alternative in the treatment of psoriasis as compared to conventional treatments with dithranol suspended in ointments and creams.

Administration, Cutaneous

[Way of drying the skin and the renewal of skin surface activity].

The author tried to evaluate the impact of the way of drying the skin upon the renewal of its surface acidity, using a linen towel, paper towel, cellucotton and a stream of dry air. 20 persons were evaluated. Prior to the study, 1% solution of "BHP" soap had been put on their skin. PH was measured at the skin surface by a pH-meter (produced by "Radelkis") using a combined glass and calomel electrode. This method of skin drying was considered the best one, after which the average time of pH value renewal on the skin surface was the shortest, which amounted to the recovery of pH to the initial value. The way of drying the skin was found to have a significant impact on the time of pH renewal. The results were indicative of advisability of the use of linen towels.

Detergents

[Effect of soap and detergents on the restitution of acidity and lipids of the skin surface].

A comparative evaluation of the effects of soaps and detergents on pH behaviour and lipids level on the skin surface and duration of their restitution was carried out. The studies were conducted in two groups. The first group of 32 persons used 1% solution of "BHP" soap, whereas the other one, composed of 31 persons, 0,5% solution of detergentpowder "POLLENA". PH measurements of skin were performed using pH--meter of Radelkis firm with a combined glass and calomel electrode. Lipids on the skin surface were determined by the Hodgson--Jones and Wheatly's gravimetric method. The evaluation of soap and detergent's effects on skin was based on the mean output and direct pH values of the skin surface, accidental and residual level of lipids, and comparison of the duration of these parameters restitution. The soap was found to alkalyse stronger than the detergent, and duration of pH restitution is longer after using the soap, whereas the detergent degreases the skin more intensively than the soap. Also restitution of lipid's jacket is slower after using the detergent.

Detergents