The effects of adding reticulo-endothelial tissue extracts to human leucocyte cultures.
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Biomedical subjects
Publications and source records attributed to G D Pegrum.
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Methods of platelet adhesiveness to glass and celite have been developed. The technical merits of these methods have been compared with a method using adenosine diphosphate (ADP). The aspects of platelet stickiness measured by the various techniques may be somewhat different. Bearing this in mind, the reproducibility of the results using each of the three methods has been assessed on a series of healthy donors.
Platelet adhesiveness has been assessed on whole blood from a series of 34 diabetics and 50 control subjects using adenosine diphosphate (A.D.P.) and by adherence to glass microspherules (ballotini). Using both techniques it was possible to demonstrate a significant increase in platelet adhesiveness in the diabetic patients.
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