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Biomedical subjects

G Freitag

Publications and source records attributed to G Freitag.

At least 55 records · Page 3Linked to original sources

[Importance of post-therapeutic computer tomography follow-up studies of patients with malignant testicular tumors].

120 patients with malignant tumours of the testicles were subjected to follow-up studies for up to 7 years after the completion of therapy. In 27 cases (22%) metastases were found, which appeared almost exclusively within the first 3 years after treatment. There was definite evidence of metastasis in 9 out of 46 cases (19%) of seminoma and with 18 out of 74 nonseminomatous tumours.

Adolescent↗

[Results of angiography studies of the solitary kidney].

Renovasography is better able than any other diagnostic method to distinguish the lack of one kidney from other anomalies and diseases which can give a false impression of this condition. In the retrospective evaluation of the renal angiograms of 3 858 patients, solitary kidney was diagnosed in 170 cases. In 123 cases the tentative diagnosis of agenesia or aplasia was confirmed by intra-aortic injection of contrast medium due to the apparent lack of the renal artery and the nephrographic effect with smooth aortic walls. In another 27 patients short remnants of the renal artery were found as the expression of a thromboembolic arteriosclerotic obstruction and 20 patients had a solitary kidney as the result of a nephrectomy. The discussion goes into the angiographic findings as regards age, sex, side, vascularization, variations of size and additional diseases of solitary kidneys.

Female↗

[Correlation of computer tomographic, kidney vasographic and histological study results in solid kidney tumors].

Computertomography evaluates renal expansion precisely. In 105 patients differential diagnosis by means of computertomography was 95% accurate. In 93% of the cases it agreed with renovasographic and histological findings. It was possible to demonstrate or exclude the intrusion of a tumour into the renal vein in 61% of cases of tumour of the left kidney and in 55% of growths on the right side. The computertomographic evaluation of the vena cava inferior was confirmed by the histological findings in 71% and 65% of the cases, respectively. It was possible to exclude lymphogenous metastasis in 89% of the cases. In 4% computertomography gave falsely positive findings. In so far as computertomographic examination can give an unambiguous evaluation of a renal growth and a certain proof or disproof of the intrusion of a tumour into the venous system is made, preoperative renovasography can be dispensed with. Information on the operability of the tumour should be supplemented by clarification of lymphogenous and distant metastasis.

Adolescent↗

[Sacrococcygeal chordomas--peculiarities of their morphology, clinical aspects, diagnosis and therapy].

Sacro-coccygeal chordomas are discussed with respect to particularities of their morphology, clinical aspects, diagnosis and therapy, including two cases treated by the authors. The consideration of almost always ignored or misinterpreted initial lumboischialgia is pointed out. Because of the primary benign growth of these tumours, early diagnosis and immediate radical surgical treatment would possibly increase the survival chance of their carriers or even--so far only a speculation--lead to permanent curing.

Aged↗

[Results of computer tomographic and lymphographic diagnosis of malignant testicular tumors].

89.5% accuracy was achieved using the pre-therapeutic combination of CT scanning and lymphography to diagnose the spread of malign testicular tumours in 28 cases. In 14% of the patients CT scanning was able to increase the diagnostic information. CT scanning should follow lymphography. The use of CT scanning to check on progress proved useful in 42 cases, both after lymphonodectomy and after irradiation therapy. In 7 cases (17%) the CT examination revealed metastasis.

Adolescent↗

[Quantitative determination of regional cerebral circulation with Xe-133: lst experiences using this method in the clinic].

After injection of the radioactive noble gas Xe133 into the A. carotis interna, the regional blood flow in the brain is determined with a 10-channel measuring unit. From the first clinical evaluation of the findings in 35 patients, the following conclusions can be drawn: 1. In epileptics, a localised hyperaemia very probary indicates a latent increased convulsive activity. 2. The measurement of the cerebral blood flow does not yield a contribution to the diagnosis of the type of cerebral tumours. 3. As a consequence of mass shifting of space occupying processes particularly endangered brain sections, also remote from the focus proper, show a localised pathological hyperaemia (morbid "luxus perfusion"). 4. Of greatest importance is the method for clearing up of pathophysiological relations, the clearing up of questions in connection with the blood/brain barrier function, and for the indications for and estimation of the results of vascular-surgical interventions.

Brain↗

[Results of computer tomographic diagnosis of the kidney].

The diagnostic value of CT scanning in kidney diseases was checked on the basis of a retrospective evaluation of the findings of 400 examinations. The significance of expansive processes could be established, with the exception of a blood-filled cyst, which was classified as malign. Even in cases of urinary stasis and unilateral renal non-functioning a comprehensive clarification of the pathological finding was possible.

Abscess↗

[Changes in the water and electrolyte contents of human erythrocytes due to Visotrast 370 during I-V urography (author's transl)].

The effect of the contrast medium Visotrast 370 on the water content and volume of erythrocytes, and on the electrolyte levels of plasma and erythrocytes during I-V urography was examined. The measurements were carried out at one, ten and 30 minutes after injection. One minute after injection there was a significant reduction in the water content and volume of the erythrocytes. The levels of sodium and potassium ions in the plasma were reduced ten minutes after contrast injection, but increased in the erythrocytes. After 30 minutes, significant changes could no longer be demonstrated. Possible causes for these changes and their effects on other organs are discussed. Certain practical conclusions are drawn.

Calcium↗

[The results of reno-vasography in the diagnosis of space-occupying processes].

In the great majority of cases the renovasography allows clear evidence concerning the dignity of a growing and displacing process. In 362 patients 200 angiographically malignant findings and 174 renovasographically benign processes were found. In 187 cases (93.5%) in malignant findings an accordance with the result of the histological examination could be achieved. In 12 cases falsely negative findings were got. 1 case (0.5%) resulted in falsely positive findings on the opposite side. In 174 circumscribed benign changes of the kidney 164 cases (94%) were judged angiographically correctly. 5 (3%) were not classified exactly. 5 (3%) showed angiographically the picture of the malignant tumour.

Adenocarcinoma↗

[Diagnosis of brain abscesses by angiography and nuclear medicine methods].

In most cases, abscesses are formed otogenically or rhinogenically. The clinical symptoms may be uncharacteristic. The diagnosis is made by employing nuclear-medical and angiographic procedures. In 40 patients suspected of having a cerebral abscess, transfemoral cerebral angiography and in 14 cases gammaencephalography or cerebral scintigraphy was carried out. Angiographically, cerebral abscesses mostly appear as avascular growths while nuclear-medical or localised increase in the activity concentration suggests a pathological finding. The symptoms are uncharacteristic and can only be attributed to an abscess process in connection with clinical and paraclinical findings.

Adolescent↗

[Diagnosis of space-occupying processes of the kidney by sequence scintigraphy and renovasography].

Proof and classification of a space-demanding process of the kidney is most successfully done by means of renovasography. The nuclear-medical investigation methods give only unspecific references to the disease. Investigation results of radionephrography, sequence scintigraphy and renovasography of 130 kidneys with space-demanding processes were comparatively evaluated. Renovasographically the findings of 35 malignant tumours, 58 solitary cysts and 37 polycystic degenerations were correctly classified. The radionephrography is of no importance for the diagnostics of space-demanding processes. The results of the sequence scintigraphy were in demands of space localised defects of parenchyma, reductions of parenchyma and one a non-functioning kidney. These findings gave rise to angiographical clarification. In the polycystic degeneration the irregular distribution of the activity in the parenchyma, multiple parenchymal defects and the enlargement of the organ referred to the disease.

Diagnosis, Differential↗

[Experiences in the determination of brain death].

The experience gained in the ascertainment of the brain death in 45 cases permits to draw the following conclusions: 1. The irreversible functional loss of the brain is in the first place diagnosed on the basis of the clinical-neurological findings. 2. The clinical ascertainment of the brain death requires a considerable amount of experience and should be carried out jointly by neurologists and anaesthesiologists. 3. By using cerebral angiography for proving the arrest of the cerebral circulation it is possible to ascertain the brain death earlier, to cut the pending time and to carry out a possibly envisaged removal of an organ in the period before the dropping of temperature and blood pressure.

Adolescent↗

[Value of kidney perfusion scintigraphy in the diagnosis of hypertension].

The investigation findings of radionephrography, sequence scintigraphy and renovasography of 35 patients with hypertension were compared with the results of the renal perfusion scintigraphy. In chronic inflammatory renal diseases, stenoses of the renal arteries and space-occupying processes a good correlation of the findings is the result. The results of the investigations allow of the conclusion that the renal perfusion scintigraphy gives the possibility of a more aimed use of the angiography in the clarification of the renal cause of a hypertension.

Humans↗