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Biomedical subjects

G Haller

Publications and source records attributed to G Haller.

27 records · Page 2Linked to original sources

The C-group pachytene bivalent with a locus characteristic for parachromosomally situated particulate bodies (parameres): a provisional map in human males.

During prophase stages of the first meiotic division in human males, an autosomal divalent in the C group (autosomes 6-12) characteristically has associated with it, at a specific locus, small, DNA-containing bodies (parameres). A pachytene chromomere map is presented, as is evidence suggesting that the parameres are disposed in two lateral loops, each of which is coaxial with one of the homologs. Stereophotographs of stacks of plates from electron micrographs of serial ultrathin sections show the parameres in their in situ configuration to be composed of tightly compacted fibrils, 85-90 A in diameter.

Chromosome Mapping↗

Chromosome structure and function in man. 3. Pachytene analysis and indentification of the supernumerary chromosome in a case of Down's syndrome (mongolism).

Recently developed pachytene maps of the two small acrocentric autosomes (numbers 21 and 22) of man have been applied to a case of Down's syndrome mosaic for normal and trisomic cells (46,XY/47,XY,21+). Trivalents in trisomic spermatocytes, and thus the supernumerary chromosome, were recognized as compatible in length and chromomere pattern with the shorter of these two chromosomes at the pachytene stage. With the exception of the region of the centromere and the short arm, association among constituents of the trivalent appeared complete.

Adult↗

Anterior spinal fusion complicated by paraplegia. A case report of a false-negative somatosensory-evoked potential.

A case of an anterior spinal artery syndrome complicating an anterior spinal fusion is reported. Besides documenting a relatively rare complication of anterior spinal surgery, the level of the lesion (T6) and the association of spinal shock are relatively unusual. Intraoperative somatosensory-evoked potentials (SEP) deteriorated only transiently and failed to reflect adequately the neurologic injury either intraoperatively or postoperatively. The shortcomings of SEP monitoring are discussed, and the recommendation is made to use the combination of SEPs with the wake-up test when possible.

Evoked Potentials, Somatosensory↗