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Biomedical subjects

G He

Publications and source records attributed to G He.

136 records · Page 8Linked to original sources

[Effect of the prevention and treatment of atherosclerosis of a mixture of Hawthorn and Motherworn].

Two groups of cocks were divided into controls and medications. High lipid food was given to both groups. The medications were given mixture of Hawthorn and Motherworn. The effect on prevention and treatment of atherosclerosis with the mixture was observed. The results showed that cholesterol, beta-lipid protein, triglyceride, blood sugar, whole blood viscosity, plasma viscosity, electrophoresis of red cell and fibrinogen in the medications were statistically lower than that in the controls. The results confirms the effect of the mixture on the prevention and treatment of atherosclerosis in the pathology section of coronary artery.

Animals↗

Treatment of postmenopausal breast cancer with bisbromoacetyl hexestrol.

Twenty five cases of advanced postmenopausal breast cancer patients were treated with bisbromoacetyl hexestrol 3 CR and 5 PR were achieved. The response rate was 32%, and the average duration of remission 6 months. Vaginal bleeding was seen in 9 cases, 4 of whom were compelled to discontinue treatment.

Aged↗

The relationship between translucency of rice grain and gelatinization of starch in the grain during cooking.

The soaked and nonsoaked rice grains were cooked by the excess water method and the steamer method, and subjected to Ranghino's test, X-ray diffraction, and microscopic observation. The starch granules in the nonsoaked rice were gelatinized at the same time as the grains became translucent during cooking. However, when the grains of medium amylose varieties and waxy rice were presoaked, the starch granules were not fully gelatinized in the translucent grains cooked for Ranghino's cooking time. The gelatinization of starch granules proceeded faster in the soaked rice and by the excess water method than that in the nonsoaked rice and by the steamer method. The cooking time and gelatinization time correlated negatively with the water content after soaking, and positively with the amylose content in the rice grains. The japonica rices were gelatinized fully in less than 20 min when the amount of water added for cooking was adequate.

Cooking↗

Regulation of plasminogen activitor inhibitor-1 in human adipose tissue: interaction between cytokines, cortisol and estrogen.

To investigate further the role of plasminogen activator inhibitor-1 (PAI-1) in human adipose tissue, the regulation of cytokines, cortisol (dexamethasone) as well as estrogen on PAI-1 were determined in human adipose tissue fragments. PAI-1 activity was increased in human adipose tissue fragments incubated for 48 h with interleukin-1beta (IL-1beta) (2.6-fold, p < 0.01) and tumor necrosis factor-alpha (2.3-fold, p < 0.01). Incubation with interleukin-6 revealed a non-significant decrease in PAI-1 activity. Parallel findings were obtained when studying the PAI-1 mRNA expression. Dexamethesone increased PAI-1 activity after incubation for 8 h (p < 0.05) and enhanced the stimulation of IL-1beta after 8 h incubation. However, after 24 and 48 h, dexamethasone significantly reduced the IL-1beta induced increase in PAI-1 activity by 24-52% (p < 0.05), accordingly, PAI-1 mRNA expression was reduced 60%. Finally, the induction of PAI-1 activity and PAI-1 mRNA expression by IL-1beta was attenuated by estrogen (17.8+/-4.9%, p < 0.05 and 20.9+/-5.8%, p < 0.05, respectively). These results indicate that multiple cytokines, estrogen and dexamethasone may be involved in the regulation of PAI-1 biosynthesis in human adipose tissue, and suggest that there are interactions between cytokines and these steroid hormones. The interplay between these hormones may be of importance for the levels of PAI-1 observed in obesity and associated states.

Adipose Tissue↗