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Biomedical subjects

G Heberer

Publications and source records attributed to G Heberer.

At least 73 records · Page 4Linked to original sources
PubMed1978

[Clinical aspects, diagnosis and treatment of organic hyperinsulinism. Experience with 46 operated patients (author's transl)].

The clinical picture of organic hyperinsulinism is presented with reference to experience in 46 operated patients. For the recognition of disease, a careful history is a decisive contribution. The hunger test showed a characteristic hypoglycemic reaction in 100%; the tolbutamide test gave a positive result in 92%. Insulinomas could be localized angiographically in 71%; in one patient this could only be done with an ERCT. The treatment of choice is operation as soon as possible. If possible, enucleation is to be given preference over pancreas resection because of the low complication rate. A search for ectopic (2%) and multiple (12%) adenomas is important. A cure was achieved in 76% of all those operated on. The hospital mortality was about 4%.

Adenoma↗
PubMed1978

[Malignant polyps and early recognized carcinomas of the rectum. Morphological aspects and selective surgical treatment (author's transl)].

The lymphatic drainage of the colon and rectum originates in the submucosal layer. Therefore metastases do not arise from carcinomas confined to the mucosa, and for the same reason the WHO lately recommended to call these lesions severe atypism. The term adenocarcinoma should be reserved in the case of infiltration of the carcinoma into the submucosa. According to the features outlined above adenomas of the rectum showing severe atypism can be removed by careful excision of the mucosa. Even adenomas containing an early diagnosed adenocarcinoma up to 2.5 cm in diameter often can be cured by a local resection of the rectal wall, if no metastases have occurred. From 1971--December 1, 1977, 12 rectal adenomas with severe atypism and 14 rectal adenomas with adenocarcinoma had been removed locally without complications. After 6 years there was no recurrence of carcinoma.

Aged↗
PubMed1978

[Surgery of hyperthyroidism: introduction (author's transl)].

Of the patients operated upon for goiter (n = 1891) within the last 10 years, 625 had hyperthyroidism. Exophthalmia was present in 22.7% toxic nodular goiter in 26.5%; the remaining patients had autonomous adenoma. The different prognosis and treatment of Graves' disease in contrast to other kinds of hyperthyroidism is discussed. The importance of radioimmunoassays and scintigraphic methods as a basis of differentiated and functional surgical treatment is emphasized. Close cooperation among all medical branches involved in the treatment of goiter is recommended.

Adenoma↗
PubMed1978

[Transvaginal surgical removal of a sacrococcygeal teratoma (author's transl)].

For the operative treatment of presacral sacrococcygeal teratomas perineal, abdominal, and combined abdominal-perineal routes are described. In this paper the transvaginal surgical removal of a benign teratoma after partial abdominal resection of the tumor in a 19-year-old woman is reported. No recurrence was observed within 5 years.

Adult↗
PubMed1978

[Substrate metabolism of muscles during the early postoperative period: the effect of glucose infusions].

Muscle substrate metabolism was studied by measuring arterial deep-venous substrate concentration differences across the forearm in metabolically healthy volunteers 3 h after abdominal surgery. Despite elevation of insulin levels following glucose infusion, no effect on muscular fractional extraction of glucose and no decrease of lactate and alanine production was found, whereas muscular lipolysis was inhibited to a normal extent and ketone utilization was reduced.

Abdomen↗
PubMed1977

Reversal of "one kidney" to "two kidney" tipe of Goldblatt hypertension in a patient with bilateral artery stenosis.

A 32-year old hypertensive woman with bilateral renal artery stenosis of more than 50% on both sides was studied. Renal vein renin levels were low (0.3 ng/ml/h on the right side and 0.42 on the left) before surgical correction of the left renal artery. Thereafter, blood pressure was only temporarily reduced. Four months later a repeat angiography demonstrated a widely patent left renal artery and the stenosis on the right side was unchanged. Renal vein renin was 5.12 on the left and 11.2 on the right. Subsequent operation on the right side lead to normalization of blood pressure. Thus, our patient seems to demonstrate in sequence the characteristics of the tow types of experimental renovacular hypertension known as "one kidney hypertension" and "two kidney hypertension". Our findings usggest that the pathomechanisms of these experimental models are operative in man too.

Adult↗
PubMed1977

[Reintervention for recurrent ulcer (author's transl)].

From 1967 to 1976, 158 patients were operated on for recurrent ulcer; of these, 75 patients had an ulcus pepticum jejuni after Billroth II. The most common causes of the p. op. ulcer arose from inadequate surgical techniques, i.e., incomplete vagotomy, retained gastric antrum, too large gastric remnant, or palliative primary intervention, such as simple closure. The results of retrospective analysis do not permit a comparison of the different procedures. Vagotomy (p.s.V.), however, is recommended because of lower mortality. Zollinger-Ellison syndrome must be ruled out before any reintervention for recurrent ulcer is undertaken.

Humans↗
PubMed1977

[Change in indications for reconstruction of supraaortic extracranial arteries (author's transl)].

Analysis of 334 patients, operated upon from 1962 till 1976 because of obstructions of the extracranial cerebral vessels demonstrates a change in the indication for reconstruction during the last years. The aspect of prophylaxis of neurological damage by prompt reconstruction becomes increasingly important which is documented by an increase of patients which were operated upon a) in the asymptomatic stage, b) bilaterally, c) for internal carotid occlusion during the stage of increasing neurological symptoms after they were selected according to certain criteria.

Arterial Occlusive Diseases↗
PubMed1976

[Reoperation in carcinoma of the thyroid (author's transl)].

From 1960 to 1975 a total of 82 reoperations were performed in patients with malignant goiter in the Surgical Clinic of the University of Munich. In reoperation as in primary surgery, the criteria for operative management and prognosis are dependent on histology (differentiated-undifferentiated carcinomas), extension of tumor, and age and sex of the patient. The need for early and radical reoperation increases with declining age, and also with limitation and differentiation of the carcinoma. Early results are presented: an accurate statement about late prognosis is not yet possible.

Adenocarcinoma↗