Biomedical subjects

G Klima

Publications and source records attributed to G Klima.

128 records · Page 8Linked to original sources

PubMedDate not supplied

Functional heart replacement with the spindle pump: first results.

The spindle pump is a nonpulsatile blood pump with a double function, i.e., it works centrifugally and represses simultaneously. The first experiences with this type of pump used as a biventricular assist device in four short-term animal experiments (up to 13 hours) are described. It can be demonstrated that in cases of a normally beating heart, this BVAD decompresses both ventricles by 60-70%, while the aortic pressure is slightly increased; on the other hand, in case of ventricular fibrillation, the BVAD with two spindle pumps maintained the entire circulation, at an arterial pressure between 80 and 90 mmHg with a flow volume between 3.5 and 4 L/min.

Animals↗

PubMedDate not supplied

[Function of the cytotrophoblast in the amniotic fluid/fetus compartment].

In the trophoblast cells of the fetal membranes, PAS-positive substances are demonstrated which are released intermittently into the intercellular space. It is incorrect to designate them as fibrinoid, since degeneratively altered material is not involved. This intracellular substance is with certainty the morphological substrate of the barrier in the region of the feto-maternal contact. It exerts a filter action and probably also acts in the sense of an immune barrier: lymphocytes cannot migrate through it in large numbers. The intercellular substance is flushed out with a flow of fluid through the remaining layers of the fetal membranes into the amniotic fluid. It passes into the fetus by swallowing movements and forms a major proportion of the meconium.

Amniotic Fluid↗