Biomedical subjects

G Kunz

Publications and source records attributed to G Kunz.

At least 73 records · Page 4Linked to original sources

PubMed1977

What does the symptom "palpitation" mean? - Correlation between symptoms and the presence of cardiac arrhythmias in the ambulatory Ecg.

The correlation between palpitations and arrhythmias was examined using 319 long term Ecgs of 167 patients. Furthermore, we attempted to determine the shortest possible recording time permitting the correct diagnosis of an arrhythmia and ST-segment changes. 31 arrhythmias (9.7%) were correctly identified by our patients; On the other hand, while there were 20 palpitations (39%) that could not be related to an arrhythmia we recorded 39 instances in which these same patients missed an arrhythmia. Tachycardias and multiple ventricular extrasystoles were most likely identified. Most of the rhythm disturbances (89%) appeared during the first 12 hours and all of the ST-segment changes eventually seen (100%) occurred until the end of 8 hours of recording. This study shows that ths symptom "palpitation" is a poor indicator of underlying rhythm disturbances. In the documentation of arrhythmias and/or ischemic ST-segment changes 8 to 12 hours of recording should usually be sufficient.

Arrhythmias, Cardiac↗

PubMed1977

[Significance of model studies for explanation of the pathogenesis of the mechanically induced birth trauma (author's transl)].

We have studied the propotions of displacements from fetal cerebral parts during simulated intrauterine pressure. Stillborn children from the death to the experiments last only some hours, were put in cephalic position in our birth model. The cavum uteri was simulated by a metal cylinder, in which we gave compressed air for simulating the labor. The pressure was held about 100 mm Hg. A rubber cuff was fixed on the metal cylinder and let an opening of 8 cm, simulating the cervix uteri. The model with the death infant in it was frozen and than the fetal head sectioned in slides of 1,5 cm in the right of the birth pressure axis. We found, that the gyri occipital were widened, opposite the gyri frontal were compressed. Parieto-occipital we found a venous blood congestion. The brain stem was kinked and displaced dorsal. In one case we carried out in the meantime an aniogram. The cerebral vessels became under the pressure elongated. This was reversible by decrease of the pressure. The limitation of such model studies are give in some facts. We do not know, how much the loosening of the skull, following the fetal death, leads to a more than normal shifting. We further do not know, which proportions of the displacements of the cerebral substance during labor from the fetus could be compensated. Our findings suggest, that it is possible, that cerebral blood flow will be altered by displacements of the cerebral masses during intrauterine pressure. But we have not exact informations about it.

Birth Injuries↗

PubMed1976

[Spine-distribution of pyramidal neurons of the CAl-region of the rat hippocampus following long-term oral alcohol administration].

The distribution of the dendritic spines in the CA1 hippocampal region of adult rats was investigated by means of lightmicroscopical and statistical methods. The rats received daily equal amounts of aethanol for a period of 52 days. The average number of spines for a part of 50 mum along the apical main dendrite raised from 35 to 36.9 spines. The average spines-density for a part of 1 mum length on the apical dendritic branches raised from 0.71 to 0.94 spines. In a similar way the average spines-density on the basal dendritic branches raised from 0.65 to 0.94 spines. According to our results received after a period of aethanol application the total number of dendritic spines of one rat CA1 hippocampal pyramidal neuron was calculated with 4177 visible spines. The value was compared with the normal value of 3029 dendritic spines. The results were discussed by the aid of additional light- and electronmicroscopical findings.

Alcoholism↗

PubMed1975