A cross-over trial was run to compare the effects of two delayed-action nicotinic acid polyesters (pentaerythritol-tetranticotinate, PETN, and inositol-hexanicotinate, MIEN) in 59 aged normo- and dyslipaemic subjects. PETN tended to normalise the lipid picture in much the same way as nicotin acid, without a drastic effect on circulating lipids and lipoproteins. MIEN, on the other hand, had only a slight effect on total blood lipids, and appeared to be ineffective or negative with respect to the other lipid parameters. PETN proved capable of releasing active concentrations of nicotinic acid in vivo for a period of time that was sufficient to correct hyperlipaemia in age subjects. The side-effects were slight, infrequent and quickly reversible.

Age Factors↗

PubMedDate not supplied

[External cardiotocography in movement. Autocorrelation technic, an initial step for external telemetric cardiotocography?].

Ultrasonocardiograms with autocorrelation technique were registered in 60 women from 24th to 41th week of pregnancy. Registration was first done in lying position for 10 minutes, then for another 10-20 minutes in sitting position, thereafter in standing position and finally during walking around. The registration quality was good with rare gaps: median range of gaptime 1-3, 6% in the lying, 0-6% in the sitting, 0-4% in the standing and 1.8-6.4% in the walking patient. Fitting corrections of the transducer were needed nearly only when changing from lying to sitting position. In 18 parturients external ultrasonocardiography in autocorrelation technique and telemetric direct fECG-cardiography gave nearly identical registrations.

Computers↗

PubMedDate not supplied

[Labor maturity of the cervix. III. Dependence of course and duration of labor on cervix criteria].

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Cervix Uteri↗

PubMedDate not supplied

[Cervical ripeness. I. The clinical criteria of assessment of ripeness and their variability at term].

Four clinical criteria of "cervical ripeness"--consistency, length, dilatation and station of the fetal head--were checked in cases of term and post-term pregnancy before labour had started, and analyzed for their variability. The frequencies in the consistency categories and also the distribution of cervical effacement indicate that in only 1 to 2,5% of all pregnant women ripening of the cervix had not yet begun at term. There were no differences in nulliparous and parous women. But about 2/3 of the nulliparous and 3/4 of the parous women had a soft cervix which was effaced 80% or more. At term the most common cervical dilatation was 1 to 2 cm in nulliparous women and 1/2 cm more in parous ones. But in only 2 to 8% there was found a dilatation of 3 cm ore more. Engagement of the fetal head was not very advanced at term, with the presenting part reaching or passing station -4 in 27% of the nulliparous and in 21% of the parous women. Only in 1% there was found a presenting part reaching station 0 at term before labour had begun. We do need further studies with serial and standardized examination to get better knowledge of the process and variability of cervical ripening in relation to duration of pregnancy, lag-time to spontaneous onset of labour, prelabour uterine activity and perhaps other conditions.

Cervix Uteri↗