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Biomedical subjects

G M Aber

Publications and source records attributed to G M Aber.

53 records · Page 3Linked to original sources
PubMed1975

Intrarenal vascular changes in patients receiving oestrogen-containing compounds--a clinical, histological and angiographic study.

Nine patients who developed reversible hypertension and/or evidence of impaired renal function whilst taking an oestrogen-progestogen-containing compound have been investigated. Serial haematological and biochemical studies have been carried out on each patient in association with selective renal angiography and renal biopsies. Abnormalities of the peripheral renal vessels have been demonstrated in all patients and a close correlation between the histological and angiographic appearances noted. The presence of microthrombi involving glomerular capillaries or intrarenal arterioles was invariably accompanied by evidence of micro-angiopathic haemolytic anaemia along with stasis of contrast medium in the intra-renal vascular circulation. Although the three different groups of patients studied tended to show their own particular intra-renal angiographic patterns, the definitive diagnosis depended on the haematological and histoligical findings. In the majority of patients, withdrawal of the oestrogen-progestogen-containing compound resulted in clinical improvement.

Acute Disease↗
PubMed1975

Intrarenal vascular changes in adult patients with recurrent haematuria and loin pain--a clinical, histological and angiographic study.

Clinical features have been correlated with renal function, histology and selective renal angiography in 19 patients with recurrent painless haematuria, recurrent loin pain, or both haematuria and loin pain in whom urinary infection, calculi and anatomical abnormalities of the urinary tract had been excluded. No deterioration in renal function was observed in any patient over periods of up to nine years. Although all patients showed similar glomerular changes histologically, consisting of focal and segmental mesangial thickening and proliferation and periglomerular fibrosis, mild tubular damage was more common in those with loin pain. All patients with loin pain whether or not they had haematuria, had abnormal renal angiograms consisting of focal or generalized vascular lesions sometimes associated with cortical infarcts. The possible aetiological factors are discussed with particular reference to oestrogen-containing compounds.

Adolescent↗
PubMed1974

Pregnancy, subarachnoid haemorrhage, and the intravascular coagulation syndrome.

Two patients are described who developed subarachnoid haemorrhage during pregnancy and the puerperium. In both patients there was clinical, haematological, histological, and renal angiographic evidence of the intravascular coagulation syndrome. No source of intracranial bleeding was demonstrated by bilateral carotid angiography in either patient. We suggest that the subarachnoid haemorrhage was a result of the intravascular coagulation syndrome in both patients.

Acute Kidney Injury↗
PubMed1972

Myopathy in association with primary hyperaldosteronism.

We report a patient presenting with a proximal myopathy in association with primary hyperaldosteronism (Conn's syndrome). The possible factors concerned in the inter-relationship of these two conditions are discussed, with particular reference to the influence of potassium depletion.

Electromyography↗