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Biomedical subjects

G M Iakovlev

Publications and source records attributed to G M Iakovlev.

At least 19 recordsLinked to original sources
PubMed1994

[Changes in clinical-instrumental parameters in patients with mitral stenosis after balloon catheterization valvuloplasty of the mitral valve].

The results of mitral valvuloplasty using a balloon catheter were presented for 104 patients with mitral stenosis. Instrumental measurements and clinical symptoms were evaluated before the operation, 6 and 12 months after it (62 and 42 patients, respectively). The balloon dilatation has increased mitral orifice from 120.5 +/- 5.8 to 333.88 +/- 7.45 mm2, transmitral diastolic pressure gradient decreased from 22 +/- 1 to 7.91 +/- 0.6 mm Hg. All the patients benefited clinically: cough, blood spitting, lower limb edemas, protodiastolic murmur disappeared, dyspnea noticeably reduced. NYHA functional class I-II was established in 85% of the patients. The highest effect was achieved in patients with isolated mitral stenosis.

Adult↗
PubMed1993

[Therapeutic effect of intravascular phosphobion during transesophageal electric cardiostimulation in patients with ischemic heart disease].

The authors propose a new method of treating coronary patients with angina pectoris of effort and at rest. It involves combination of transesophageal pacing with simultaneous intravenous administration of phosphobion. The treatment given to 10 coronary patients produced positive antiischemic and hemodynamic effect against its absence in control subjects treated conventionally with ATP.

Adenosine Triphosphate↗
PubMed1993

[The use of an automated teaching system in a therapy department].

At the division of general therapy N 1 of the Kirov Military Medical Academy a version of automated training system was elaborated for the IBM AT/386 users of MS DOS operational system. The knowledge text control was carried out during the lessons at the display classroom equipped with Wyse-85 terminals ("Wyse Technology Company"), DEC VT 220 regimen, and connected up to PC IBM AT/386 which works in multiterminal function. Application of text control has shown that the volume of knowledge had increased up to 82-90%, but it was right only for the groups where the methodics of classes with application of the results of text controls was strictly adhered. The progress in other groups was less than 68%.

Computer-Assisted Instruction↗
PubMed1992

[Stage-by-stage diagnosis in conducting the cardiological screening of servicemen using a computer].

A 3-staged algorithm and a device named PKSV-01 were worked out to carry out a pre-doctor screening of servicemen. This method made it possible to define the sound servicemen, as well as patients with cardiovascular diseases including ischemic disease and postinfarctional cardiosclerosis. The specificity came to 91.9-93.9%, and sensitivity up to 81.4-97.8%. The application of lineal discriminative function ensured 93.1% of the right answers.

Cardiovascular Diseases↗
PubMed1991

[The biochemical and immunological indices in the rehabilitation period of the victims of the accident on the Komsomolets atomic submarine].

Biochemical and immunological indexes of peripheral blood were compiled in military sanatorium "Divnomorskoe" in seamen who have suffered from general supercooling in the result of "Komsomolets" atomic submarine breakdown. The patients had the symptoms of metabolic disturbance, immunodepression, a great concentration of proteins in acute phase and activity of MB-fraction of creatine phosphokinase. Immunodepression after the general supercooling was mainly conditioned by oppression of differentiation, metabolic changes and functional activity of T-lymphocytes. A course of immunocorrective therapy was employed using "thymogen"--synthetic peptide of thymus. In the process of rehabilitation there was a gradual functional recovery, normalization of metabolism and immunological indexes.

Accidents↗
PubMed1991

[The correction of secondary radiation-induced immunodeficiencies].

The influence of the ionizing radiation upon the human organism is accompanied by the formation of the secondary radiative immunodeficiencies, which can be treated with the help of immunomodulating preparations of microbiotic, animal and plant origin, as well as compounds obtained by chemical synthesis. The comparative analysis of the various immunomodulators has shown that the peptide preparations of thymos and bone marrow, referred to the cytomedinum class (thymalinum, thymogenum, haemalinum) were most perspective for the correction of the secondary radiative immunodeficiencies. The scheme of thymalinum application in the treatment of radioactive affections of immune system is enclosed.

Drug Therapy, Combination↗
PubMed1990

[The prediction of recurrent acute pneumonia morbidity in young persons].

The authors examined 103 patients suffering of acute pneumonia. A group was distinguished that suffered frequently of this disease. It is shown that repeat pneumonia has its clinical and immunological particular features. Formulas are described allowing to predict repeat morbidity and, thus, permitting to take measures of prophylaxis.

Acute Disease↗