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G Müller

Publications and source records attributed to G Müller.

At least 721 records · Page 40Linked to original sources

[Equipment to find odour compounds, produced by bacteria in drinking water. I. Comparison of a bacteria produced odour compound with a chemical reference substance and a simple method for getting and concentrating biogenic odour compounds (author's transl)].

An increase in using surface water and bank filtration processes as raw water for drinking water production sometimes gave rise to problems of bad taste and odour. Some of these odourous compounds may be produced by bacteria, especially Streptomyces species. They are able to pass active carbon filters and therefore are a problem as well in raw water as in treated water. Biogenic odourous compounds often are soluble in water, that means they are present without being fixed to the bacteria cell. Human nose is able to percieve even dilutions of about 10(-9). If a bacterial produced substance is compared with an equal smelling chemical substance such as Isoborneol, also diltuions of 10(-9) may be smelt. Gas-chromatography only detects concentrations up to 10(-5), so the nose is much more efficient.

Filtration↗

[On cobyrinic acid biosynthesis. Novel methylated hydroporphyrins and their role in cobyrinis acid formation (author's transl)].

Clostridium tetanomorphum and Propionibacterium shermanii were examined for intermediates in the synthetic pathway uroporphyrinogen III leads to cobyrinic acid. The isolation of two novel methylated hydroporphyrins, whose methyl groups are derived from S-adenosyl-L-methionine, is described. Spectroscopic (field desorption-mass, visible absorption) und electrophoretic studies as well as incorporation of labelled substrates indicate that they are analogues of a dihyrouroporphyrin and a tetrahydrouroporphyrin with adjacent reduced rings. Field desorption spectra of the [C2H3]- and [CH3]-tetrahydrouroporphyrin analogues show that the compound contains two methyl groups; it is concluded that the chlorine-like compound has one methyl group. Dehydrogenation experiments indicate that the methyl groups are located at one beta-carbon of the reduced rings. Incorporation experiments suggest that the tetrahydrouroporphyrin-like compound is an intermediate in cobyrinic acid biosynthesis. Studies on the utilization of a heptacarboxyporphyrinogen from C. tetanomorphum for cobyrinic acid formation are also described.

Clostridium↗

[On the preparation of intermediates in cobyrinic acid biosynthesis by suspensions of Propionibacterium shermanii (author's transl)].

The preparation of a dimethyltetrahtdrouroporphyrin (Faktor II or sirohydrochlorin) using suspensions of Propionibacterium shermanii as well as a promising method for the isolation of tetrapyrrols with at least four carboxy substituents from cell-free extracts and growth media are described. Also a Faktor II-analogue with three methyl groups which are derived from L-methionine is reported. Incorporation experiments indicate that this is an intermediate in cobyrinic acid formation. Because of this, and from spectroscopic (field desorptionmass, visible absorption) studies it is concluded that the "extra" methyl group is located at the meso-carbon between two methylated reduced rings.

Propionibacterium↗