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Biomedical subjects

G Mackensen

Publications and source records attributed to G Mackensen.

At least 19 recordsLinked to original sources
PubMed1988

[Iridocyclectomy using a lamellar explorative technic. Long-term studies].

The question as to whether lamellar explorative iridocyclectomy always enables the spread of tumors of the iris base or ciliary body to be detected beyond doubt was verified in 11 patients who had been treated by this procedure more than four years previously. Seven of the patients were available for reexamination. In two special cases it was found that this was not true. In the other patients neither histologic findings nor long-term follow-up revealed any tumor spread beyond the excision area, and in particular no invasion of the sclera.

Aged↗
PubMed1985

[Surgical indications in glaucoma].

A number of aspects of glaucoma surgery are discussed. Complete drainage of the aqueous via the subconjunctival space results in underperfusion of the trabecular meshwork, leading to significant impairment of the trabecular function. In certain cases, therefore, we prefer trabeculotomy, even though its pressure-lowering effect is inferior to that of fistulizing surgery: trabeculotomy preserves the unaffected trabecular meshwork. Laser trabeculoplasty has the advantage of increasing the outflow facility. In angle-closure glaucoma, iridectomy is performed as an initial procedure in every case in order to eliminate pupillary block. The transcorneal approach ensures watertight wound closure and preserves the conjunctiva for fistulizing surgery if necessary. Glaucoma surgery can usually be performed in lid akinesia and subconjunctival infiltration. This alternative helps to avoid retrobulbar injection when the optic nerve is already severely damaged by glaucoma.

Anesthesia, Local↗
PubMed1979

[Long-term follow-ups of iris sutures (author's transl].

Previous reports from the Freiburg Eye Clinic concerning surgical techniques and experiences with iris sutures are complemented by this description of long-term follow-ups (up to 8 years, 6 1/2 years on average) of a random selection of 65 eye which underwent surgery. There were no harmful reactions to the suture of the suture material (nylon, 30 micrometers). Three-fourths of the eyes examined presented with tissue bridges, indicating fibroblastic unification of the sutured tissues. Even where there was preoperative atrophy of the connected iris parts (following glaucoma attacks with iris infarction) the connection remained stable over the years. These long-term follow-up findings support earlier recommendations concerning indication and surgical technique.

Follow-Up Studies↗
PubMed1978

Progress in cataract surgery using microsurgical technique.

A microsurgical technique for cataract extraction is presented. The operations were performed with a corneal incision and a continuous nylon 10-0 suture. This technique is evaluated by the study of 1289 cases, consecutively operated on. The complication rate was very low. Haemorrhage in the anterior chamber was found in 1%. Delayed reformation of the anterior chamber occurred in only two cases. No cases of iris prolapse occurred. The intraocular pressure was not interferred with by the operation. Wound rupture following removal of the suture three months post-operatively occurred in 1%. The advantages of the corneal incision and continuous nylon suture are discussed (less irritation, good and secure wound closure).

Cataract Extraction↗
PubMed1978

[Suture loosening after keratoplasty and methods for correction (author's transl)].

An analysis of histological and clinical findings in 102 keratoplasties confirms that suture loosening is often associated with defects found in Bowman's membrane and in the superficial stroma. These structures of the cornea serve as the major supporting layer for a suture. In cases of more generally weakened corneal tissue, like in keratokonus, suture loosening is also a relatively frequent occurance. In this paper we report on our experiences with correction methods, post-operative care and immunoprophylaxis after correction.

Corneal Transplantation↗
PubMed1978

[Cataract extraction combined with trabeculotomy (author's transl)].

In this paper we report on a series of 56 eyes which underwent a combined cataract-trabeculotomy operation. After a follow-up of at least 6 months. 63% of the eyes had normal intraocular pressure while 34% of them required further medication to achieve the same. No serious complications were observed.

Cataract Extraction↗
PubMed1977

[Keratoplasty in childhood (author's transl)].

Report on 36 keratoplasties (30 eyes) in children up to 15 years of age. An efficient postoperative care was of critical importance for the final outcome. The specific problems are discussed. Regarding the fact that generally children are only operated on in case of heavy corneal disease which brings about a higher risk of graft failure our results may be judged as "fair": 63% of the transplants were optically clear; 43% exhibited good and 30% fair functional results. The best results were achieved with keratoplasties in corneal dystrophies (keratoconus included). Another group with good results was that with herpetic corneal disease, whereas transplants after heavy perforating injuries mostly failed. A beter postoperative medical collaboration and consultation is needed to improve final results. This is especially true for correcting operative measures (loosening sutures) and for therapy and prophylaxis of graft reactions.

Age Factors↗
PubMed1977

[Herpes therapy and prophylaxis. II. Results of a survey of practicing ophthalmologists (author's transl)].

Between December 1975 and April 1976, 2,300 ophthalmologists in the Federal Republic of Germany and West-Berlin were asked about their experiences with different forms of therapy and prophylaxis for herpetic eye diseases. 15 questions were answered by 965 ophthalmologists (42%). The answers not only reflect their preferences and experiences, but could also initiate a new evaluation of many diagnostic, therapeutic and prophylactic methods.

Humans↗
PubMed1976

[A method of closing fistulae from drainage blebs to the out-side after glaucoma operations (author's transl)].

A method for closing fistulae in drainage blebs after anti-glaucoma surgical procedures is described. Its aim is to line internally and support the wall of the bleb, including the fistula, with subconjunctival tissue. The decisive factor in achieving this is the firm anchoring of the subconjunctival tissue pulled down between the corneo-scleral opening and the thin conjunctival tissue layer.

Conjunctiva↗
PubMed1976

[Late complications with anterior chamber lenses (author's transl)].

6 intraocular lenses (type Dannheim) which had given good optical results after implantation had to be removed after 7-19 years because of keratopathy, iritis, and secondary glaucoma. The most important finding was an advanced arrosion of the supporting supramide loops. This often caused breaking of the loops and was a major factor for late complications.

Adult↗
PubMed1975

Animal experiments on an absorbable synthetic thread made of polyglycolic acid (PGA) in corneal surgery.

Monofilaments of the absorbable synthetic thread Dexon made from PGA have properties similar to nylon 10-0. Experiments with intra-lamellar implantation of the monofilament in rabbit corneas showed the same good material tolerance as nylon 10-0. Perforating corneal wounds were closed with interrupted and running sutures from PGA monofilaments, respectively. One week post-operatively, increased intraocular pressure caused a wound rupture but not a thread rupture. Two weeks post-operatively an increased intraocular pressure of more than 300 mm Hg could no longer rupture the wound. Slit lamp and histological examinations revealed symptoms of absorption after the second week. According to our findings, PGA monofilaments may be suitable for corneal surgery in patients.

Absorption↗