Biomedical subjects
Publications and source records attributed to G Magni.
Adsorption to Matrex Gel Green A and successive elution with uridine provides a one-step procedure for the purification of uridine phosphorylase from Escherichia coli B. The homogeneous preparation of the enzyme can be obtained within a single day with an activity recovery above 80%.
Eight couples, in which one of the partners is alcoholic, have been studied with the aim of verifying Bateson's hypothesis according to which the relationship between the alcoholic--when sober--and the other is clearly symmetrical. To this purpose a new method developed by the author and based on the Rorschach Test has been utilized. Although the small number of subjects in this pilot study precludes any detailed statistical analysis, some preliminary findings appear to be particularly interesting: (a) clear prevalence of symmetrical exchanges on complementary ones, which seems to confirm Bateson's hypothesis; (b) greater number of 'up' positions of the non-alcoholic partner who seems the one who 'controls' the relationship. In this perspective the symptom can be explained as an attempt to gain control of what is to happen in the relationship with the partner.
Explore the source record for details and available documents.
In some cases, chronic pain is due not to an organic cause but rather to psychologic factors. Among these, chronic pain as a depressive equivalent is particularly interesting. By this term, we mean a painful state caused by depression and manifesting itself almost entirely in this somatic form, thus making diagnosis difficult. There are, however, some features that may positively orient diagnosis: age at onset and sex, clinical history, presence of a subdepressive state, attitude during the medical examination, absence of delusions and hallucinations, and the Rorschach test pattern. These features permit correct differential diagnosis and justify pharmacologic therapy with antidepressants.
Explore the source record for details and available documents.
Life events reported to have occurred twelve months before the onset of the illness were compared in 55 in-patients who had a first episode of myocardial infarction and 55 control in-patients matched for age, sex, marital status and social class and afflicted with acute abdomen, trauma and multiple trauma. The Paykel interview for Recent Life Events was used. Myocardial infarction patients reported significantly more previous events than the control group (p less than 0.001) with more undesirable (p less than 0.01) and uncontrolled (p less than 0.01) events. Moreover, myocardial infarction patients had significantly more events (p less than 0.01) which had an "objective negative impact" (rated as being traumatic). These findings are consistent with the view that certain recent life events have a positive association with the onset of a first episode of myocardial infarction.
Explore the source record for details and available documents.
Psychological distress in parents of children with acute lymphatic leukemia was evaluated by means of the Symptom Distress Checklist. This scale was administered twice: within a few days after the child's admission to hospital and 8 months later. Twenty-five consecutive, unselected subjects were compared with controls matched for age, sex, marital status and social class. At the first evaluation the sample presented higher mean scores than the controls for anxiety (P less than 0.005), depression (P less than 0.005), sleep disturbances (P less than 0.005) and obsessions (P less than 0.05). An 8 months' follow-up confirmed the persistence of anxiety (P less than 0.05), sleep disturbances (P less than 0.05) and above all depression (P less than 0.005).
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The effects of viloxazine hydrochloride on the libido and sex drive of 20 outpatients suffering from minor depression were assessed. For this purpose the Zung Self-Rating Depression Scale and a questionnaire devised by the authors to evaluate libido and sex drive were used. A dose of 300 mg viloxazine/day for 4 weeks was administered. Test-retest assessments showed a significant improvement of depression and an increase in libido and sex drive. These latter effects were marked, but did not appear to be related to the improvement of depression.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The aim of the study was to assess psychological distress in duodenal ulcer (DU) and acute gastroduodenitis (AGD). Sixty-one consecutive, unselective patients (DU = 25; AGD = 36) were compared with their respective controls matched for age, sex, level of formal education, and social class. Psychological distress was assessed using the Kellner-Sheffield Symptom Rating Test. In order to reduce to the minimum the possible effects of the duration of the symptoms and awareness of the diagnosis, the study was carried out before diagnosis on subjects whose symptoms were of recent onset. The DU and AGD patients had higher mean scores than the controls for neuroticism and anxiety; moreover the mean scores for depression and somatization of the AGD patients were also higher than those of the controls. On the basis of these data, the authors discuss the possibility that gastroduodenitis might be an independent entity or part of the spectrum of acid peptic (ulcer) disease.
Explore the source record for details and available documents.