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Biomedical subjects

G Neumann

Publications and source records attributed to G Neumann.

At least 73 records · Page 4Linked to original sources
PubMed1984

[The significance of vaginal fluid substances as growth media in genital mycosis].

By means of thin layer chromatography amino acids, lipids and phospholipids were detected in the vaginal fluids of pregnant and nonpregnant women with and without vaginal yeast colonization. Though pregnancy and/or yeast colonization do not seem to alter qualitatively the spectrum of amino acids and lipids of the vaginal fluid, an influence is supposed of these substances - like that of glucose - on growth and metabolism of the yeasts and on the clinical manifestation of vaginal candidosis.

Amino Acids↗
PubMed1983

Electrokinetic properties of polymer and glass surfaces in aqueous solutions: experimental evidence for swollen surface layers.

Streaming potential and streaming current measuring techniques have been applied to polymer and glass surfaces to study solid/liquid interface electrical properties. The streaming current technique provides a reliable electrokinetic potential value, preexcluding surface conduction. A combination of both techniques results in experimental evidences for swollen, gel-like layers at (even apolar) polymer surfaces. Protons and hydroxide ions are the potential-determining ions indicated by the dependence of streaming potential on pH. Human serum albumin adsorption at a glass surface is discussed in terms of spatial distribution of the fixed macromolecular electric charges.

Adsorption↗
PubMed1982

[Use of histoacryl tissue adhesive in iliac crest biopsy].

In the up to now most customary methods of the biopsy of the iliac crest it was usual to shut the incision of the skin necessary for the intervention after having finished the biopsy with a clamp or a suture, which, as a rule could be removed together with a fracture bandage covering all only after a week, which on principle made necessary a repeated consultation of the physician. The restrictions in the development of physical activities or in the settlement of hygienic necessities (prohibition of shower and bath) showed that these methods are unsuitable for the diagnostic interests in sports medicine. Therefore on 41 test persons or patients 44 biopsies were performed with a modified technique after Jamshidi and Swaim, using histoacryl tissue adhesive as closure of a wound. The course without complications and the shortening of the time up to the removal of the protective bandage to 2-3 days show, that this technique is suited also for the application in sports medicine and in so-called "risk biopsies".

Adult↗
PubMed1982

[The trend in tumor incidence and its possible relation to early diagnosis].

In the Federal Republic of Germany age depending participation in the Cancer Screening Programme as carried out by the social health insurance is completely contrary to mortality: high participation in age groups with low mortality and vice versa. Thus the impact of the programme on the epidemiology of malignant tumors is rather limited. In 1977 the expected mortality of cancer of the colon, rectum, breast, or prostate was higher than expected in spite of the screening programme being effective since 1971. Mortality of cancer of the cervix uteri is in most age groups lower than expected, even more than may be due to a high screening effect. But in 1980 35.1 percent of all cases of death by malignancies of the uterus were not specified by site. Thus mortality of cancer of the cervix uteri is of restricted value. By a small study conducted in Stuttgart 1976/77 it may be estimated that about 23 percent of the unspecified cases are cases with cancer of the cervix. 6.6 percent could not be specified definitely.

Female↗
PubMed1982

Regeneration of rectal mucosa and recurrent polyposis coli after total colectomy and ileoanal anastomosis.

Two patients with adenomatous polyposis of the colon who had been treated by colectomy, stripping of rectal mucosa, transrectal pull-through of terminal ileum, and ileoanal anastomosis were found--after seven and three years--to have recurrent polyposis in the rectal segment, consequent to regeneration of the rectal mucosa. The latter might have resulted form retraction of the implanted ileum or sloughing of its mucosa, followed by upward growth of epithelium from the strip of anal mucosa retained above the dentate line at the time of surgery. Colonic metaplasia of the implanted ileal mucosa may be an alternative explanation. In all patients who have had this operation for polyposis coli, the rectal segment should be reexamined by endoscopy and biopsy to rule out recurrent polyposis or replacement of ileal mucosa by colorectal mucosa.

Adenoma↗
PubMed1982

[Advances in the radiological diagnosis of VIIIth nerve tumours (author's transl)].

Where there is suspicion from the audiological and vestibular findings of an VIIIth nerve tumour, radiographs of the skull and of the petrous bones (Stenvers) should be obtained. This should be followed by computer tomography with intravenous contrast medium (a plain series can be omitted in these cases). A negative or indefinite scan should be followed by CT performed after air insufflation. Vertebral angiography is valuable as a pre-operative investigation for tumours larger than 3 cm. Ordinary tomography of the petrous bone in sagittal, lateral or stenvers projection or cisternography with air, oily or aqueous contrast medium need not be carried out.

Adult↗
PubMed1981

Characterization of retinoic acid-induced alterations in the proliferation and differentiation of a murine and a human melanoma cell line in culture.

We employ the murine S91 and the human Hs939 melanoma cell lines for the characterization of various biochemical changes induced by retinoids. Retinoic acid (RA) causes a time-dependent, and reversible reduction in cell proliferation rate in liquid medium and inhibits growth in agar. The proportion of cells in the G1 phase of the cell cycle increases in RA-treated cells, and the uptake of TdR, UdR and Leu decreases. The growth inhibitory effect of RA is apparently not mediated via labilization of lysosomes, increase in cAMP or changes in the synthesis of prostaglandins or polyamines. Exposure to RA stimulates tyrosinase activity and increases melanin content severalfold over the levels found in untreated cells. Various retinoids exhibit the activities of RA; however, their potencies vary depending on their structure. Those possessing a free -COOH at C-15 are usually more effective than those with a different group or with a derivatized carboxyl. A positive correlation exists between the ability of retinoids with a free -COOH in C-15 to inhibit growth and to bind to an RA-binding protein found in the S91 melanoma cells. Future studies will explore recently discovered changes in the glycosylation of cell surface components and their relationship to the phenomena described here.

Animals↗