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Biomedical subjects

G Roche

Publications and source records attributed to G Roche.

At least 73 records · Page 4Linked to original sources

[Doxapram. Pharmocokinetic and clinical study].

Two series of work are reported. The first concerns the pharmacocinetic study of the product after it was administered through different ways and the corresponding evolution of PaCO2. The second study concerns the effect on pulmonary arterial pressure, blood gases and some parameters of ventilatory mechanics, of a perfusion of 200 mg of this product over a two hours period.

Administration, Oral↗

[Anuric tubular nephritis caused by rifampicin allergy].

Starting again a Rifampicin treatment gave rise to an acute renal insufficiency, reversible by hemodialysis. This incident resulted from an immunopathological conflict revealed by the presence of anti-Rifampicin antibodies. Renal needle biopsy did not show any immune deposits. The mechanism of these incidents is discussed. Authors draw attention to the necessity of avoiding discontinuous Rifampicin treatment.

Acute Kidney Injury↗

[Pleural effusions (chylous or nonchylous) with regional osteolysis: A case evocative of Gorham's disease].

In connection with one case of thoracic localized osteolysis associated to bilateral seral effusion, serohemorrhagic on the right, chylous on the left, the authors recall 13 similar observations. In this localization a pleural effusion is very frequent and specific to it, putting at stake the vital prognosis of the patient. These observations can be compared to multiple osteolyses and be grouped together under the name of "intraosseous capillary ectasies".

Adolescent↗