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G S Strelin

Publications and source records attributed to G S Strelin.

28 records · Page 2Linked to original sources
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[Effect of autologous marrow transplantation on bone marrow recovery following large-field fractionated irradiation of dogs].

After large-field fractionated irradiation of dogs at a cumulative dose of 54 Gy, a stable bone marrow depletion occurs persisting for a year following irradiation. The automyelotransplantation after the end of the exposure elicits a transient recovery of the exposed bone marrow, 1.5-2 months after the beginning of irradiation, followed by a secondary depletion of the exposed haemopoietic sites. The control and the automyelotransplanted animals exhibited bone marrow recovery one year and six months after irradiation, respectively, the cellularity being maintained at a high level for 3 years of observation.

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[Correlation of spleen colony formation and changes in spleen weight during its recovery in irradiated mice].

In experiments on (CBA X C57Bl)F1 and BALB/c mice it was shown that with the spleen mass increasing, due to exo- and endorepopulation, during the postirradiation regeneration of the spleen, the number of splenic colonies also increases to a certain level. When the spleen mass reaches 1/3 of that lost after irradiation the number of discrete colonies decreases. When the spleen mass is restored to about 1/2 solitary colonies do not form at all. The spleen mass can considerably exceed the normal level in conditions of intensive repopulation.

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[Effect of endotoxin on the migration of hematopoietic colony-forming cells and on the repopulation of hematopoietic organs in partially irradiated mice].

In experiments on (CBA X C57BL)F1 hybrids it was shown that the administration of sublethal doses of endotoxin to locally exposed (spleen, 9 Gy) animals enhanced the repopulation of the exposed haemopoietic tissue (spleen and bone marrow). It is concluded that endotoxin has a favourable action on the recovery of haemopoiesis of partially irradiated mice which confirms the idea of the possibility of using stimulators instead of autotransplantation of bone marrow from intact parts.

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PubMedDate not supplied

[Patterns in the spiral formations of insects].

Regular features of spirals of chitinous filaments of tracheas were investigated in 12 species of insects. All species studied were found to have mosaic heterochirality, i.e. portions of opposite directions of curling in the trachea system, and prevalence of rightness or leftness in them. The percentage correlation of rightness-leftness are characteristic of each species and may be considered as hereditary features. The degree of prevalence of the rightness or leftness in some species as well as the degree of chiral purity (according to this parameter) is not connected with the direction of curling. The tendency to chiral purity is distinctly seen in species with both the right and left curling. As for the problem of species formation, it should be admitted that the independence of the curling direction on the one hand, and the prevalence of its degree--and the degree of chiral purity--on the other hand, speaks in favor of different mechanisms of their development. It is also confirmed by the fact that the distribution of the curling direction is referred to the whole complex of species while the degree of prevalence of any kind of curling and the degree of chiral purity are distinctive individual characteristics and are developing as a result of the adaptation selection, in connection with other features of the given species. At the same time, in accordance with some scientists it may be supposed that the directions of curling is developing on the basis of molecular structures and are thought to be accidental. Regular features of curling of trachea formations are different depending on localization of organs. For example, the tracheas feeding the malpighian vessels form spirals curling around every malpighian vessel and always to the right. Neither the trachea, nor the vessels form spirals without being in contact.

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