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Biomedical subjects

G Santoni

Publications and source records attributed to G Santoni.

At least 55 records · Page 3Linked to original sources
PubMed1986

[Chorioretinal changes in the course of sympathetic ophthalmia].

A case of sympathetic ophthalmitis is reported. A bull's eye chorioretinopathy was observed with electroretinographic changes (augmentation of latencies and disappearance of oscillatory potentials) which regressed in a short time. The authors believe that the retinal changes could be secondary to an autoimmunological reaction, responsible for the sympathetic ophthalmitis.

Adolescent↗
PubMed1985

Recurring bilateral hypopyon in chronic myeloid leukemia in blastic transformation. A case report.

There have been many reports in the literature on keratohypopyon in acute leukemia. We report a case of a 40-year-old-man with chronic myeloid leukemia who developed bilateral, recurring kerato-hypopyon, the first manifestation of which appeared during intrathecal chemotherapeutic treatment just after an episode of leukemic meningiosis. There was no involvement of the CNS at the time of the relapse of kerato-hypopyon.

Adult↗
PubMed1985

Gammaglobulins and immunocomplexes in aqueous humor and serum of patients with senile cataract.

The authors have measured the gammaglobulins and the immunocomplex levels (CIC) in aqueous humor and serum of 14 patients (3 males and 11 females) over 50 years old, who were affected by different types of cataract. Even if the authors have examined a limited number of samples, the results confirm the previous data which also showed very low levels of IgG, IgA, IgM, IgE, CIC in aqueous humor.

Aged↗
PubMed1984

[Microangiopathy and retinal dystrophy].

Two cases are described of an association of retinal dystrophy and a vasculopathy similar to Coat's disease. The first case was a female adult in whom the two sets of symptoms appeared almost simultaneously. In the second case the disease appeared in infancy, evolved rapidly during adolescence and led to blindness. In both cases, the vasculopathy developed over several years and then stabilised; in contrast, the dystrophy, which was of the paucipigmentary type, continued to get worse. From these two cases, and others described in the literature, it appears that many causes can be involved in the association of the two syndromes. A genetic factor that has been demonstrated in several families was not present in these two patients; there appears to have been an immunological or inflammatory process, not yet identified, that became active at the time of the rapid evolution of the dystrophy.

Adolescent↗
PubMed1983

[Responses of isolated hepatic artery segments to barium in the presence of a flavonoid (4-methylesculetin), indomethacin and acetylsalicylate].

The aim of this work is to study the mechanism by which 4-methylesculetin (4-Me) inhibits the Ba++ induced contraction in smooth muscle. The effect of 4-Me, alone or associated with ascorbic acid, on basal tone and Ba++ induced contraction of isolated hepatic artery strips have been studied. Experiments have been carried out in the presence of lysine acetylsalicylate (LAS) and indomethacin (IN), specific inhibitors of prostaglandin-synthetase. Both LAS and IN suppressed the depressive effect of 4-Me on the Ba++ dependent contraction. Therefore, it seems reasonable to conclude that the 4-Me influence could be mediated by prostaglandins release smooth muscle.

Animals↗
PubMed1983

Urinary mercapturic acid in chemical workers and in control subjects.

Mercapturic acid urinary excretion was followed in a control group and in chemical workers exposed to toxic and mutagenic compounds. Chemical workers had a significantly lower excretion of mercapturic acid when compared with controls. Smoking effects were not significant statistically. No correlation was found between urinary mutagenic activity and mercapturic acid urinary excretion.

Acetylcysteine↗
PubMed1983

[Report of an atypical case of Goldenhar syndrome].

The authors report an atypical case of Goldenhar syndrome characterized by hemifacial and cranial hypoplasia associated with severe microtia and anophthalmia on the right side, antimongoloid palpebral fissures, epibulbar epidermoid, corneal anesthesia and preauricular tags on the left side. The bilateral presence of characteristic features of Goldenhar syndrome is rare and lends support to the possibility that the patient presents an intermediate form of developmental defect of the first branchial arch. The differential diagnosis is discussed.

Adolescent↗
PubMed1982

[Choroidal miliary tuberculosis: fluoroangiographic study (author's transl)].

The authors have followed the evolution of disseminated choroidal tuberculosis during a period of 16 months. At the beginning of the disease, fluorescein angiography showed an early 'screen effect' and later a 'focus effect'. During the later stage of the disease, the pigmented epithelium was seen to be involved as well, as demonstrated by (1) the presence of advanced pigmented chorioretinitis at the sites where the tubercles were observed at the beginning of the disease and (2) the presence of fluorescent areas early during fluorescein angiography.

Adolescent↗