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Biomedical subjects

G Santoni

Publications and source records attributed to G Santoni.

At least 73 records · Page 4Linked to original sources
PubMed1981

[Degenerative choroidal atrophy (author's transl)].

Based on of 10 personal observations, the authors discuss the modes of onset and the various clinical, functional and genetic aspects of primary degenerative choroidal atrophies. Central areolar atrophy may be the only lesion or is sometimes associated with other signs of a more extensive degeneration (fundus flavimaculatus, degeneration of the posterior pole). Among the diffuse forms a familial case is reported which can be interpreted as a sectorial hypoplasia, and a case similar to a choroideremia, but with recessive transmission.

Adult↗
PubMed1980

[Retrobulbar injection of chlorpromazine in the absolute glaucoma (author's transl)].

The retrobulbar injection of a mixture of 2,5% of chlorpromazine + 2 % of novocaïne in blind and severely painful eyes was followed by a marked improvement of the subjective simptomatology in 82,5 % of the 63 subjects tested. The averaged follow-up was 2,6 years (range within 4 months and 8 years). Safe, simple and lacking in systemic involvement, the treatment with chlorpromazine can be proposed like a valide alternative to enucleation.

Adult↗
PubMed1979

The effect of the epidermal growth factor (EGF) on the corneal epithelium in humans.

Epidermal growth factor (EGF) is a polypeptide hormone present in mammalian organs. In vivo, it shortens the time course of the corneal reepithelialization by stimulating a marked cell proliferation of the corneal epithelium. A further direct effect in vivo has been confirmed on human corneal epithelium and epidermis in culture. Tests in several nondystrophic diseases of the corneal epithelium confirmed the observations previously made in the rabbit that EGF accelerates the process of epithelial healing. The integrity of the corneal stroma is prejudicial for the maximum effect of the EGF, in the sense that the deeper the stroma is damaged, the less EGF acts. In herpetic lesions EGF is effective within 48 h only when the virus-affected area of the corneal epithelium has been scraped off. EGF is proposed as a new and efficacious agent for increasing the restorative process of the corneal epithelium in many nondystrophic diseases.

Adolescent↗