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Biomedical subjects

G Teng

Publications and source records attributed to G Teng.

11 recordsLinked to original sources

Empathic accuracy in a clinically relevant setting.

This study addressed 3 questions regarding empathic accuracy in a clinically relevant setting. First, does the empathic accuracy of a perceiver improve with increased exposure to a target individual? Second, can empathic accuracy be enhanced by providing the perceiver with feedback about the target's actual thoughts and feelings? Third, are there stable individual differences in empathic accuracy that generalize across different targets? The results indicated that although absolute performance levels varied from 1 target to another, empathic accuracy generally improved with increased exposure to the target. In addition, feedback concerning the target's actual thoughts and feelings accelerated the rate at which the perceivers' empathic accuracy improved. Finally, cross-target consistency in responding (alpha = .86) revealed stable individual differences in the perceivers' empathic ability. Implications of these findings for clinical training and practice are discussed.

Divorce

[The effects of nucleus central lateralis on the unit discharges in posterior group of thalamic nuclei evoked by splanchnic afferents in cats].

The effects of the nucleus central lateralis (CL) on the unit discharges evoked by the splanchnic afferents in the posterior group of thalamic nuclei (PO) were studied with extracellular microelectrode techniques. In 35 cate, 96 units (98%) producing evoked discharges in PO with the latency range of 30-150ms were observed. The evoked discharges of 69 units in PO were depressed by stimulating CL with a short train of electric pulse through a bipolar electrode, but the other 27 units were uninfluenced. The inhibition of CL can be classified into 3 forms: the instant inhibition, the delayed inhibition and the continued inhibition. The injection of picrotoxin (1%, 40 microliters) into lateral ventricles of the brain could invert the inhibitory effects of PO cells caused by stimulating CL. The results suggest that there may be direct nervous pathway from CL to PO and some of these neurons may function with GABA as neurotransmitter. The CL may execute the instant inhibition through the nervous pathway. It is concluded that CL has inhibitory effect on visceral pain and GABA is involved in the inhibitory process.

Animals

[Study on unit discharges of the posterior group of thalamic nuclei evoked by electric stimulation of centromedian nucleus in cat].

The unit discharges of posterior group of thalamic nuclei (PO), evoked by stimulating greater splanchnic nerve (SPL) and centromedian nucleus (CM) respectively in cats were studied with extracellular recording method and stereotaxic techniques. The evoked potentials of 63 neurons in PO by stimulating SPL and 16 ones in PO by stimulating CM were observed in 26 cats, indicating that PO might be one of the representative areas of the splanchnic afferent pathway and there might be a nervous projection between CM and PO. Moreover, convergence of unit discharges produced by stimulating CM and SPL in PO was found, suggesting that pain signals from the viscera and impulses from CM can interact each other at PO.

Animals

[Recording intracellular potentials of viscero-nociceptive neurons in posterior group of thalamic nuclei (PO) and their labeling with HRP intracellularly in cats].

Intracellular potentials (ICP) of the neurons in PO evoked by stimulating greater splanchnic nerve (GSN) were recorded in 42 cats. The resting potentials and action potentials induced by stimulating GSN were 53.74 +/- 11.68 mV and 29.44 +/- 9.22 mV respectively. Owing to intensity of the stimulation we can record EPSP and single spike or polyspikes on it. The action potentials derived from stimulating GSN (related action potentials) were inhibited by injection of morphine intravenously. On the basis of recording ICP, we also labeled 2 related neurons with stimulation of GSN and 2 unrelated ones. Differences between two kinds of the neurons were compared preliminarily. The ICP of the related neuron with stimulating GSN were inhibited by stimulating Amygdala too. Factors influencing amplitude of action potential in intracellular recording, criteria of determining nociceptive neuron and inhibition derived from stimulating Amygdala were also discussed.

Action Potentials

[The inhibitory effects of stimulating AC, AL, BNST and AHL on visceral pain].

We took the unit discharges of the neurons in the posterior group of thalamic nuclei (PO) caused by stimulating the great splanchnic nerve (GSN) as an indicator of visceral pain. We searched for the effects of electrical stimulating central nucleus of amygdala (AC), lateral nucleus of amygdala (AL), bed nucleus of striae terminalis (BNST) and lateral area of hypothalmus (AHL) on unit discharges of PO and the relationship among these nucleuses. The result indicated that the inhibitory effects were strongest with stimulating AC, the next was with stimulating AHL, then BNST and AL. The inhibitory percentages were 85.7% (AC), 62.9% (AHL), 53.1% (BNST) and 54.2% (AL) respectively. The inhibitory effects of stimulating AC couldn't be canceled by injecting naloxone intravenously. AC may be more important for the antinociceptive system than AL, BNST and AHL. There was no relationship between AC and BNST on the inhibition of unit discharges. The inhibitory effects of stimulating AL may be related to AC.

Amygdala

Intracellular potentials of visceronociceptive neurons in posterior group of thalamic nuclei and its labeling with HRP intracellularly in cat.

The intracellular potentials (ICP) of 42 visceronociceptive neurons related to stimulating greater splanchnic nerve (SPL) in Posterior group of thalamic nuclei (PO) were investigated. We analyzed the electrophysiological features, such as amplitude of resting potentials and action potentials of the neurons. Following acquisition of electrophysiological data, (HRP) was injected into 3 neurons, whose responses were inducted by stimulating SPL (related neurons) and able to be inhibited by morphine intravenously. Two neurons revealing spontaneous discharges but are not able to evoke response by stimulating SPL (non-related neurons), also were stained by HRP. Two kinds of neurons, related and non-related ones, display different dendrite branching patterns.

Action Potentials

[Responses of neurons in the somato-sensory area I to noxious electric stimulation of nervus peroneus communis. The study of intracellular potentials].

Noxious electric stimulation of nervus peroneus communis (PN) results in pain. It hasn't been reported that the neurons in somatosensory area I (SI) may respond to the noxious stimulation. In this paper, using intracellular microelectrode technique, we have studied the responses of neurons in SI to noxious electric stimulating PN. 33 neurons were recorded in 18 cats. 16 neurons were related with the noxious stimulation. The responses of these neurons to noxious stimulation were mainly inhibitory postsynaptic potentials (IPSP). Some neurons responded with two IPSPs. A few neurons responded with EPSP (Excitatory postsynaptic potential)-IPSPs. The latencies of the first IPSPs were short (8.25 +/- 5.90ms) and showed that the first IPSPs might be induced by the input of A beta fiber. The latencies of the second IPSPs (In the neurons with two IPSPs) were long (60.33 +/- 6.62 ms) and showed that the second IPSPs might be induced by the input of A delta fiber. Above results show that: 1) SI neurons can respond to the noxious electric stimulation of PN. 2) The responses of SI neurons to the noxious stimulation were mainly IPSPs. 3) The second IPSPs might be related with pain.

Animals

[Effects of stimulating periaqueductal gray on the nociceptive neuron discharges of post-thalamic nucleus evoked by stimulation of splanchnic nerve in cats].

The effects of stimulating periaqueductal gray (PAG) on the nociceptive neuron discharges of pronucleus evoked by stimulating the splanchnic nerve in cats were studied. The two kinds of inhibitory action were observed. One was called early phase or prompt inhibition phase which occurred within 30 ms to 150 ms after stimulation of PAG. The other was called slow-pase or sustained inhibition which occurred from a few minutes to more than ten minutes after the stimulation of PAG. The results showed that PAG played an important role in the analgesia of visceral pain. Both kinds of inhibition may be blocked by naloxone, this suggests that endogenous opiate like substances involved in these inhibitory processes caused by stimulating role in the inhibitory effect of PAG.

Animals

Invariance in the MMPI's component structure.

Bernstein and Garbin (1985b) suggested that the Minnesota Multiphasic Personality Inventory's major clinical scales (excluding Scales ? and 5) can be approximated by an oblique three-component structure: (a) Profile Elevation, (b) Test-taking Attitudes, and (c) Optimism-Pessimism, collectively termed the salient weight model. In this study, we found that both this model and the MMPI's principal component structure remain invariant across race, sex, and, as previously noted, context of testing (job applicants vs. inmates in correctional institutions). We further noted that several alternative definitions of Profile Elevation provide equally satisfactory representation of the relations among the scales. This factor invariance is necessary, but not sufficient, for the MMPI to be viewed as unbiased.

Adult

Evaluation of estradiol in aspirated ovarian cystic lesions.

During a three-year period, 217 ovarian cystic lesions were evaluated by both fine needle aspiration (FNA) cytology and estradiol (E2) assay at Royal Women's Hospital. One hundred three ovarian lesions were subsequently subjected to histologic examination, and 79 cyst fluids were assayed for progesterone. Of the 151 cystic lesions diagnosed by cytology/histology, 50 were follicular cysts, and 90% had E2 content > 20 nmol/L. The remaining 101 nonfollicular cystic lesions represented a heterogeneous group, but 99% had E2 content < 20 nmol/L. The sensitivity of E2 content > 20 nmol/L for follicular cysts was 90% and the specificity 99%. In contrast, progesterone was elevated in follicular cyst fluid but also in many other types of cysts. Consideration of E2 content in the 66 cysts undiagnosed by histology/cytology revealed 33 follicular cysts. The precise nature of the 33 nonfollicular cystic lesions remains unknown, and further investigations, including surgery, are warranted. It is concluded that E2 assay, unlike progesterone assay, constitutes a useful ancillary diagnostic clue in the evaluation of ovarian cystic lesions in the premenopausal woman.

Biopsy, Needle