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Biomedical subjects

G Urumov

Publications and source records attributed to G Urumov.

At least 19 recordsLinked to original sources
PubMed1990

[The diagnostic potentials of spatial velocity ECG in assessing the changes in ventricular depolarization].

The study includes 702 patients (with left ventricular load, myocardial infarction and bundle branch block) and 130 healthy persons. To all these a spatial velocity EKG was made (SVEKG) as well as corrected orthogonal electro- and vectorcardiogram according to Frank, spatial ECG and standard EKG in 12 leads. The indices of the spatial velocity ECG were compared with those of the other methods on the basis of the criteria sensitivity and specificity. In the patients with right ventricular load the indices of the spatial electrocardiography showed the highest sensitivity; in the patients with left ventricular load and bundle branch block the indices of the corrected orthogonal electrocardiography showed the highest sensitivity. In the patients with myocardial infarction the potentials of several methods were equal. The insufficient number of investigations concerning the spatial velocity ECG cannot give a clear view of its potentials and its place in the clinical practice but some of its advantages make it very convenient for preparing a system of automatic analysis of the heart electrophysiological signal.

Bundle-Branch Block↗
PubMed1989

[Complex assessment of the electrophysiological changes in patients with right-ventricular cardiac loading].

In 216 patients with right ventricular cardiac overload the changes of 76 electrophysiological indices were studied--indices of the corrected orthogonal electrocardiogram after Frank, corrected orthogonal vectorcardiogram, spatial electrocardiogram and high-speed spatial electrocardiogram. The patients with right ventricular cardiac overload are divided into two basic groups--patients with systolic and patients with diastolic overload. The indices are assessed on the basic criteria of sensitivity, specificity and realization. Variation analysis as well as statistical comparison with 119 healthy persons are performed. On the basis of the results of the study "sets" of 4 indices each with 97-98% sensitivity are determined, indices from all methods used are included in the "sets". The conclusion is reached of the good possibilities of the electrophysiological methods when a combination of indices with the help of a computer is made.

Adult↗
PubMed1989

[Complex assessment of the electrophysiologic changes in patients with left-ventricular cardiac overload].

130 healthy persons and 146 cardiac patients with left ventricular cardiac overload were examined by 4 electrophysiologic methods: corrected orthogonal electrocardiogram according to Frank, corrected orthogonal vectorcardiogram, space electrocardiogram, high-speed space electrocardiogram. 76 indices were examined. The cardiac patients were classified into two basic groups: patients with systolic overload and patients with diastolic overload. By variational analysis, performed in all patients, statistically significant differences were found between the cardiac patients and the healthy persons. On the basis of the criteria sensitivity, specificity and assessment of realization the best indices for every method were determined. In order to improve the sensitivity "sets" with sensitivity of 91-96% are established by mathematical calculations. The "sets" are made up of 4 indices from different methods and are suitable for inclusion in computer programs.

Aortic Valve Insufficiency↗
PubMed1988

[Assessment of the information value of pain and ST depression in the exercise electrocardiographic test].

200 patients (181 men and 19 women) with stable stenocardia were examined by the exercise tolerance test. The patients were loaded by the step by step method on veloergometer or threadmill up to 80% of the maximal pulse rate. 126 of the tests were evaluated as positive. False positive were 10 tests and 19 tests were false negative. The coefficient of sensitivity (independently of the limiting factor) was 82.2%, the specificity was 80%, the prognostic value of the positive test was 91.6%, of the negative test--68.3%. The sensitivity coefficient was: in the patients with one affected arterial branch--81.3%; in the patients with two affected arterial branches--80.4%, in the patients with three affected arterial branches--92.5% and in the patients with affection of the main arterial stem--87.5%. The patients were classified into three groups according to the expression of the limiting factors: I group with limiting factor pain (98 patients) with sensitivity coefficient 74.3%, specificity--77.8%, prognostic value of the positive test--89.1% and of the negative test--55.5%. II group with limiting factor ST-depression (83 patients) with sensitivity coefficient 71.3%, specificity--91.7%, prognostic value of the positive test--95% and of the negative test--61.1%. III group with limiting factors both pain and ST-depression with sensitivity coefficient 45.4%, specificity--91.7%, prognostic value of the positive test--95% and of the negative test--61.1%. The main conclusion from the study is that the limiting factor ST-depression as a basic objective sign of myocardial ischemia has high enough specificity and prognostic value and should be considered as a limiting factor with greatest informatory value.

Angina Pectoris↗
PubMed1987

[Choice of the anti-arrhythmia drug and antitachycardia pacemakers in persistent tachycardias].

In 57 patients with recurrent tachycardiac attacks in whom the empiric medical drug treatment failed to prevent the attacks electrophysiological examination was carried out in order to specify the type of the tachycardia. This was followed up by a serial testing of drugs. In 41 patients an antiarrhythmic drug (or a combination of drugs) was found which could prevent the attacks. The prospective follow up of these patients from 3 months up to 4 years revealed that in 36 of them there were no more tachycardiac attacks (90% efficacy). In 11 patients antitachycardia pacemakers were implanted with great efficiency. 9 of the patients had pacemaker type extinguishing and the other two patients had atrio-ventricular pacemaker by a double path in the AV-node. The selection of and antiarrhythmic drug by means of electrophysiological testing and the antitachycardia pacemakers are efficient means against recurrent tachycardias.

Anti-Arrhythmia Agents↗
PubMed1986

[Reproduction of tachycardias in patients with WPW syndrome].

Intracavitary electrophysiological study of the heart (IES) was carried out in 27 patients with WPW syndrome. In 17/27, permanent tachycardia, reentry type was reproduced, in 1/27--unstable and in 2/27--echo phenomenon, in 1/27--atrial fibrillation. In 6/27 no tachycardia was reproduced. In I patient the tachycardia, type reentry "detained" in atrial flutter, and in 2--in ventricular tachycardia (unstable). In all patients IES established the presence of additional connections between auricles and ventricles: to left auricle--9 patients (5 obscure connections out of them), to right auricle--6 patients, to septum--10 patients, James connection--1 and connection of Mahaim--1 patient. IES is a valuable method for reproduction of tachycardia in the existence of anatomic base (additional connection) and proper electrophysiological characteristics (short refractory phases). In parallel with tachycardia, reentry type, atrial and ventricular tachycardia could develop in the patients with WPW, making use of the additional connection. IES contributes to the elucidation of numerous diagnostic and therapeutic problems in the patients with WPW.

Adolescent↗
PubMed1979

[Clinical use of electrical atrial stimulation].

Electric auricle stimulation (EAS) was realized in a total of 77 patients. In 60 of the patients EAS was performed as a hypoxic test (step-wise increase of heart rate, with ECG registration and in many of the cases -- registration of certain indices of general and intracardial hemodynamics) with a view to precise diagnosis of ischemic heart disease and assessment of myocardial contraction function. In 91 per cent of the patients with stenosed coronary pathology on coronarogram, the symptoms of coronary insufficiency were positive (pain attack, ECG changes via ischemic type and/or deterioration of the myocardial functional curve) with the aid of EAS. Various correlations were established between the manifestations of coronary insufficiency and the deterioration of the functional curve of left ventricle. Furthermore, in the majority of the cases, one way results, among the data of veloergometry, coronarography and EAS, were recorded. In some cases EAS provided additional data for coronary insufficiency with negative veloergometric test (7 patients) and negative coronarography (5 patients). EAS could be applied in the diagnostics of ischemic heart disease, and in a hemodynamic aspect, via EAS a myocardial loading is realized with a minimum change of cardiac index and aortic pressure. In 16 patients EAS was applied with a view to the investigation of the functional state of sinal node and heart conduction system. In 13 patients, data about the syndrome of morbid sinal node were found (pathologic time of sinal node restoration) or for a latent lesion of heart conduction system. In the other three patients the suspicion of syndrome of morbid sinal node was not confirmed. The data obtained contributed to the determination of the therapeutic approach of those patients. In 5 patients a high frequency auricle electrostimulation was applied successfully in the interruption of paroxysms of supraventricular tachycardia. EAS was concluded, on the base of the data obtained, to be appropraite for application and precise diagnosis of ischemic heart disease, as well as in the studies on sinal node state and heart conduction system. In some rhythm disturbances, resistant to medicamentosus treatment, the electric auricle stimulation could prove a valuable therapeutic method.

Coronary Disease↗
PubMed1979

[Planimetric analysis of ventricular depolarization on Frank's corrected orthogonal electrocardiogram in healthy hearts and in patients with ventricular loading].

Nineteen planimetric indices of 110 cardiac healthy subjects, 141 patient with left ventricle loading and 136 patients with right ventricle loading are analyzed. On the base of the variation analysis and determination of statistically significant differences, it was established that in right-ventricular loading the following indices deviate from the norm: ASX, AQZ, AQRSX, AQRSz, SAQRSx, SAQRSy, SAQRSz, SAS, SAQRSg, whereas in left-ventricular loading -- ARx, ARz, AQRSx, AQRSz, SAQRx, SAQRSy, SAQRz, SAR, SAQRSg. At a second stage, the sensitivity of the separate indices from the groups with left ventricular and right-ventricular loading was amalyzed, as well as the separate subgroups (pulmonary stenosis, aortic stenosis, mitral stenosis, interauricular defect, arterial hypertension, mitral or aortic insufficiency. The results were compared with those of axial indices, obtained from another investigation of the authors. The planimetric analysis was established to be more complex than the axial and the index SAQRSg to be with the best sensitivity in the cases with hemodynamically lightly loaded musculature.

Analysis of Variance↗
PubMed1978

[Significance of sinus rhythm for ventricular function].

The changes in hemodynamics in conditions of dosed loading prior to and post cardioversion were followed up in 21 patients with valvular defects or atherosclerotic myocardiosclerosis and absolute arrhythmia with auricular fibrillation. In conditions of auricular fibrillation all the patients showed data about a deteriorated ventricular function (increased arterial-venous difference--tachycardia), both at rest and at dosed loading. One week after the sinus rhythm restoration, a considerable improvement of ventricular function was observed, at rest and loading (normal arterial-venous difference, higner minute and beat volume), suggesting the favourable effect of the restored sinus activity. The improved ventricular function is due to the restored auricular contraction, together with the restoration of rhythmic cardiac activity.

Adult↗
PubMed1978

[Electrophysiological methods of assessing myocardial hypoxia].

The potentialitis of the standard electrocardiogram, precordial cartogram and spatial analysis are confronted in 38 patients with extensive anterior or anteroseptal myocardial infarction, acute phase, in order to determine the extent and propagation of the myocardial hypoxia. The determination is performed on the base of the correlation dependence as regards the creatinine-phosphokinase level in blood. The best degree of correlation dependence has the spatial analysis of the changes in the segment ST - Vmax ST sp. r=0.69, as well as the changes in the segment ST reflected in the precordial electrocardiography - nST-0.1 mv. r=0.67. Close is the degree of correlation dependence in the standard electrocardiogram - STv r=0.59. The difference in the correlation coefficients are not statistically significant, allowing their application in the routine work of the three methods.

Acute Disease↗
PubMed1978

[Comparison of precordial electrocartography with pathologicoanatomic data on 20 patients with recent myocardial infarct].

In 20 patients with recent myocardial infarction, that died till the 40th day after the onset of the disease, a comparison is made of the data from the pathologoanatomical findings with the indices from the precordial electromapping. The changes in the ST segment of the precordial electromapping correlate, to a significant extent, to the weight of the infarction zone in patients with interior site of the myocardial infarction (sigmaST r = 0.89, p less than or equal to 0.01; nST r = 0.62, p less than or equal to 0.01). The indices from the precordial electromapping characterizing the changes in depolarization, are with a considerable less degree of correlation dependence to the weight of the enfarcted zone in the same patients (nQS r = 0.62, p less than or equal to 0.62, p less than or equal to 0.05; sigmaAR r/0.45, p less than or equal to 0.05). In patients with posterior and/or inferior site of the infarction the correlation dependence to the indices from the precordial electromapping is less manifested.

Adult↗
PubMed1978

[Precordial electrocartography (mapping) in cardiac infarct].

After a detailed literature survey the authors share the results from the precordial electromapping with the registration of 30 points upon the chest in 34 patients with ischemic heart disease (30 with transmural infarction and 4 with intermediary syndrome). The following indices were followed up: sigmaST (the sum of the elevation of ST segment measured at 60 msec of the S deflection recording) and the index nST (the sum of the points with an elevation greater than 0.1 mV/1 mm). Both indices well correlate to the level of blood creatine phosphokinase, determined 24 hours after the examination. Due to the close degree of correlation dependence, the two indices are interchangable for the practice. The precordial electromapping reflects the degree of extent of the "myocardial hypoxia" as well as the degree of the disturbed biological activity of the tissues, affected by the myocardial infarction.

Acute Disease↗