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Biomedical subjects

G V Murthy

Publications and source records attributed to G V Murthy.

At least 19 recordsLinked to original sources
PubMed2001

A population-based eye survey of older adults in a rural district of Rajasthan: II. Outcomes of cataract surgery.

PURPOSE: To assess the outcomes of cataract surgery in rural northwest India. DESIGN: Population-based, cross-sectional study. PARTICIPANTS: A total of 549 cataract-operated persons (723 operated eyes). METHODS: Cluster sampling was used in randomly selecting a cross-sectional sample of persons 50 years of age or older for visual acuity measurement, refraction, and slit-lamp and direct ophthalmoscope examination early in 1999. Those operated on for cataract were queried as to the date and place of surgery. The principal cause of reduced vision was identified for all examined eyes with presenting visual acuity worse than 6/18. MAIN OUTCOME MEASURES: Presenting and best-corrected visual acuity and cause of vision loss. RESULTS: Presenting visual acuity was less than 6/60 in the better eye in 33.7% of cataract-operated persons and greater than or equal to 6/18 in both eyes in 8.2%; 31.7% were bilaterally operated on. Of cataract-operated eyes, 44.1% initially had visual acuity less than 6/60 and 31.5% greater than or equal to 6/18; with best correction, the corresponding percentages were 14.0% and 61.5%. Intracapsular cataract extraction was used in 92% of cases, and 66% had been operated on in surgery camps. Surgical complications were common and a major cause of vision impairment. In multiple logistic regression modeling, female gender and residence in a rural area were associated negatively with both presenting and best-corrected visual acuity outcomes, and surgery conducted before 1990 was associated negatively with best-corrected visual acuity. Place of surgery and subject schooling were not associated with vision outcomes. CONCLUSIONS: Cataract surgery subjects in rural areas of India that are without adequately equipped facilities and skilled surgeons, and lack of availability of intraocular lenses, are not realizing the full sight-restoring potential of modern-day surgery. Emphasis on the quality of cataract surgery outcomes must be increased to keep pace with that being given to increasing surgical volume.

Aged↗
PubMed2001

A population-based eye survey of older adults in a rural district of Rajasthan: I. Central vision impairment, blindness, and cataract surgery.

PURPOSE: To assess the prevalence of central vision blindness and cataract surgery in older adults in rural northwest India. DESIGN: Population-based, cross-sectional study. PARTICIPANTS: A total of 4284 examined persons 50 years of age or older. METHODS: A random selection of village-based clusters was used to identify a population sample in the predominantly rural Bharatpur district of Rajasthan. Eligible subjects in the 25 selected clusters were enumerated through a door-to-door household survey and invited to village sites for visual acuity testing and eye examination early in 1999. The principal cause of reduced central vision was identified for eyes that had visual acuity worse than 6/18. Independent replicate testing for quality assurance monitoring took place in participants with reduced vision and in a sample of those with normal vision in five of the study clusters. MAIN OUTCOME MEASURES: Presenting and best-corrected visual acuity and lens status. RESULTS: A total of 4728 eligible persons in 2821 households were enumerated, and 4284 (90.6%) were examined. The prevalence of presenting and best-corrected visual acuity worse than 6/60 in both eyes was 11.9% (95% confidence interval: 10.0%-13.9%) and 6.1% (95% CI: 4.7%-7.4%), respectively. Presenting blindness was associated with increasing age, female gender, lack of schooling, and rural residence. Cataract was the principal cause of blindness in one or both eyes in 67.5% of blind persons, with uncorrected aphakia and other refractive error affecting 18.4% in at least one eye. The prevalence of cataract surgery was 12.8% (95% CI: 11.6%-14.0%), with an estimated 65.7% of the cataract blind operated on; low surgical coverage was associated with lack of schooling. CONCLUSIONS: Blindness, particularly blindness because of cataract, continues to be a significant problem among the elderly living in remote areas of rural northwest India. Increased attention should be given to reaching women and the illiterate.

Age Factors↗
PubMed2001

The use of a newspaper insertion to promote DIY testing of vision in India.

BACKGROUND: The mass media have the potential to motivate people to participate in self appraisal of their own health status. An innovative communication package was designed to help people to examine vision at home. The impact of publishing the "do it yourself" (DIY) kit in Indian newspapers was evaluated. METHODS: A pretested bilingual vision testing kit was published in three newspapers. The kit comprised four tumbling Es corresponding to 6/12 line of Snellen's optotypes. Directions on using the kit were enclosed. 3 -7 days after publication of the kit, a telephone survey of newspaper readers was undertaken to evaluate the impact and cost effectiveness. RESULTS: 603 people were contacted over the telephone. 125 (20.73%) subscribed to the newspaper carrying the DIY insertion. 43.2% (54) noticed the insertion of which 88.89% (48) read the enclosed instructions carefully. 58.33% respondents felt sufficiently motivated to contact an ophthalmologist. Graduates had a 3.83 times higher probability of reading the communication insertion compared with others. Differences in relation to other demographic variables were not statistically significant. CONCLUSIONS: Newspapers are an excellent medium for communicating self appraisal kits for vision testing. The medium is cost effective and has significant reach in the urban agglomerates of India.

Adolescent↗
PubMed1999

Visual outcomes after cataract surgery and cataract surgical coverage in India.

Visual outcomes of 2369 cataract operated persons(3655 eyes) across seven major Indian states were assessed in 1998. This is the largest ever study over the past decade in the country. 9.54 per cent of the examined population had undergone operation for cataract in one or both eyes. Intra-capsular cataract extraction was the commonest surgical modality adopted (91.62%). Intraocular lens implants resulted in better visual outcomes with 71.4 per cent of such patients achieving a good visual outcome (> or = 6/18 in operated eyes). Visual outcome was also good if ICCE operated patients were provided good quality aphakic spectacles. There were no gender differentials in surgical uptake rates. The risk of poor postsurgical visual outcome was strongly associated by type of surgery (Adjusted OR for ICCE-2.78; 95% CI: 1.41-5.49) and the non-availability or poor quality aphakic spectacles (Adjusted OR for poor/no spectacles 4.59-95% CI: 3.53-5.97). Duration since surgery and the source of surgery did not influence visual outcomes. Half the cataract blind remained unoperated in the study population.

Aged↗
PubMed1999

Monitoring visual outcome of cataract surgery in India.

Two simple methods of assessing visual outcome following cataract surgery were evaluated in India. The first used data obtained from standardized patient records of cataract surgery. The second used data from population-based rapid epidemiological assessments. Analysis of 4168 hospital and eye camp records showed that, with the available standard correction, a good outcome (visual acuity > or = 6/18) was achieved in 37.8%, a borderline outcome (visual acuity 6/246-6/60) in 45.6% and a poor outcome (visual acuity 6/60) in 16.6% of instances. Of 2401 aphakic/pseudophakic eyes examined in a cross-sectional population-based study, outcome was good in 43.5% and poor in 26.4%. For 776 eyes examined in a similar study in a different state, outcome was good in 49.9% and poor in 23.9%. These assessments indicate that outcome with available correction was poor in 15-25% of eyes following cataract surgery. Visual outcome is likely to improve when better correction for aphakia can be provided. Further assessment of the causes of poor visual outcome is needed. The visual outcome following cataract surgery could be monitored on a regular basis by ophthalmologists, using either of the methods evaluated, an exercise which in itself is likely to improve the outcome of surgery. When the proportion of poor outcomes is high (> 10%) further investigation into the causes is warranted.

Cataract Extraction↗
PubMed1999

Risk factors for pediatric presumed microbial keratitis: a case-control study.

PURPOSE: To evaluate risk factors for pediatric presumed microbial keratitis and to describe the clinical picture, microbiologic spectrum, treatment modalities, posttreatment sequelae, and visual outcome in cases of pediatric presumed microbial keratitis. METHODS: A case-control study design was used to identify the risk factors associated with pediatric presumed microbial keratitis. Fifty cases of fresh corneal ulceration aged 12 years or younger were compared with 50 controls. The study variables included were age, gender, immunization status, nutritional status (weight for height), and socioeconomic status. The clinical presentation of the cases with corneal ulceration, microbiologic spectrum, and treatment modalities also were evaluated. All the cases were followed up for a minimum of 3 months, and the posttreatment sequelae and visual outcome were analyzed. RESULTS: The mean (+/- standard deviation) age of children with corneal ulceration and controls was 4.8 (+/-3.8) years and 5.1 (+/-2.8) years, respectively. Incomplete immunization status (AOR [95% confidence interval (CI)], 1.34 [0.62-2.9]) and poor nutritional status [AOR (95% CI) 1.06 (0.68-1.6)] were not found to be the predictors of corneal ulceration. Lower socioeconomic status was significantly associated with the occurrence of corneal ulceration [AOR (95% CI) 1.52 (1.1-2.3)]. Corneal trauma (38%) and systemic illness (24%) were the most often associated predisposing factors. Seventy percent of the cases were culture positive. Staphylococcus (70%) species was the most frequently isolated, followed by Pseudomonas aeruginosa (10%). Fungi were isolated in five eyes. Postresolution visual acuity at 3 months could be recorded only in 31 eyes and a visual acuity of 6/18 or better was achieved in 22% of these cases. CONCLUSION: Corneal ulceration in pediatric age group in India is associated with poverty.

Body Height↗
PubMed1999

Qualitative research in ophthalmic sciences.

Qualitative research was the preserve of social scientists before making inroads into medical sciences, as the medical fraternity was wedded to evidence-based medicine. Qualitative research methods are now being increasingly used in medicine. The goal of qualitative research is to help in the understanding of social phenomenon in their natural settings. These methods help to unravel mysteries relating to complex human interactions and to study the role of human behaviour in health and disease. Recent evidence points to the complementary roles of qualitative and quantitative methods in medical research. Qualitative methods include observations, interviews, focus groups, projective techniques, analysis of personal documents and accounts, sorting and ranking, and case studies. This communication describes the application of qualitative methods in ophthalmic research.

Humans↗
PubMed1998

Sex difference in age at onset of schizophrenia: discrepant findings from India.

Consecutive male (n=100) and female (n=100) DSM-IV schizophrenics newly registered for treatment in a large psychiatric hospital were examined with regard to age at onset of the first psychotic symptom. Age at onset of the first psychotic symptom did not differ between the sexes regardless of whether schizophrenia was diagnosed by DSM-IV or by several alternative systems. Age at onset defined by other criteria, namely age at first contact with a physician, and age at first admission for psychiatric care, also did not show any differences between the sexes. Survival analysis of subjects having a documented date of birth revealed a female preponderance at younger ages. A higher positive symptom score predicted older age at onset of the first psychotic symptom in the total sample. These findings call into question the universality of the traditional view of a younger age at onset of schizophrenia among males. Tentative neurodevelopmental and cultural explanations are presented to explain why there is no sex difference in age at onset of schizophrenia in India.

Adolescent↗
PubMed1997

Cataract related blindness in India & its social implications.

The prevalence of blindness in India is 14.9 per 1000. Eighty per cent of this blindness is due to cataract alone. Most of the cataract blinds in the country are in the rural areas while the surgical service delivery network is concentrated in the urban areas. Thus a large proportion of patients in the rural areas continue to remain blind. This situation has many social implications. There is loss of productivity, breakdown of interpersonal relationships, depressive manifestations, loss of self esteem and most patients lead an isolated humiliating life. Patients lack information on the available services and continue to remain blind for years even after being diagnosed as operable. This is unfortunate because cataract surgery is one of the most cost effective health interventions known and most operated patients, irrespective of the surgical technique, are immensely satisfied with the level of visual rehabilitation after surgery.

Aged↗
PubMed1997

A study of ocular morbidity among elderly population in a rural area of central India.

A cross-sectional study was conducted in five randomly selected villages in Wardha district of Maharashtra state to study the magnitude and factors related to the prevalence of ocular diseases among the elderly population. A total of 903 persons above 50 years were screened. The prevalence of low vision was 32% while that of blindness was 12.2%. Ocular morbidity rate was 1.21 lesions per elderly person and it increased significantly with increasing age (p < 0.001). Ocular diseases were found to be more prevalent among males, low socio-economic status group and landless labourers (p < 0.001). There was a high prevalence of refractive errors (40.8%), cataract (40.4%), aphakia (11.1%) followed by pterygium (5.2%), glaucoma (3.1%) and corneal opacities (3%). Prevalence of diseases of the lens and iris increased significantly with increasing age (p < 0.001). There is a need to evolve strategies for reducing the burden of ocular diseases and improve geriatric eye health under the existing infrastructure of health care delivery in our country.

Aged↗
PubMed1996

A follow-up study on visual outcome after camp-based intracapsular cataract extraction.

The visual outcome of 164 intracapsular cataract extractions (ICCE) performed in 158 patients at an eye-camp was evaluated. 93.3% had a preoperative visual acuity of less than 3/60. On the 4th/5th post-operative day, 39.3% had a visual acuity between 6/18 and 6/36; 84.7% had vision better than 3/60. Six weeks post-operatively, 44.1% had visual acuity better than 6/18 and a total of 84.1% better than 3/60. The vision of 40.7% improved between the 4th/5th post-operative day and the follow-up visit at 6 weeks. 46.4% of patients had post-operative corrected visual acuity better than 6/18, 24.3% had vision between 6/18 and 6/36, and a total of 84.3% had vision better than 3/60. The patients' satisfaction in terms of improvement in mobility and ability to do housework at 6 weeks after the operation correlated better with the improvement in vision in terms of the number of Snellen's lines than with the actual post-operative visual acuity.

Aged↗
PubMed1996

Community-based investigation of an outbreak of acute viral conjunctivitis in urban slums.

Nine hundred and sixteen people from 143 randomly selected households were included in this community-based investigation of an outbreak of acute viral conjunctivitis in urban slum communities of Delhi in 1994. During the 2-weeks recall period, 456 (49.8%) had conjunctivitis and 229 (25%) were symptomatic at the time of this investigation. Overall, females had a higher attack rate than males (P < 0.05). The attack rate increased with age (P < 0.001). A total of 61.6% of the conjunctival swabs were antigen positive as evidenced by indirect immunofluorescence assay. Viruses could be isolated from 30.3% of the samples processed. Out of these, 70% were identified as Coxsackie A 24 and 30% as EV 70.

Acute Disease↗
PubMed1996

Assessment of cataract surgery in rural India. Visual acuity outcome.

A socio-epidemiological assessment of what happens to the visual outcome after camp-based intracapsular cataract extraction was conducted in 6 villages and periurban areas in North India. 120 patients (143 eyes) were included in the study. The mean age at cataract extraction was 64.39 (range 33-83 years). 44.7% of the operated eyes obtained a good vision ( > or = 6/18) while 39.9% had low vision (6/24-3/60). The duration since the cataract extraction was seen to influence visual outcome. 70% of the respondents were satisfied with the surgical outcome. 76% of those with unilateral aphakia and 8.3% of those with bilateral aphakia were regularly using spectacles. 58.3% were satisfied with the spectacles. Dissatisfaction was generally due to lack of visual improvement. The major benefits accruing to the patients were improved personal activity, increased mobility and recognition of family members. It is our opinion that camp-based intracapsular cataract extraction with aphakic correction is still an important alternative in rural India.

Activities of Daily Living↗
PubMed1995

Where do persons with blindness caused by cataracts in rural areas of India seek treatment and why?

The utilization of eye care facilities by patients with a cataract was evaluated among 240 patients selected from eye care camps that were conducted by our center. Of the patients, 52.9% had visited previous eye care camps, while 19.2% consulted private ophthalmologists. Easy accessibility, reputation of a facility, competence of its staff, free service, and nearby facilities were the major reasons that were cited by patients for utilization of service facilities. Distance, monetary constraints, and a lack of professional trust, escorts, and the perception about the seriousness of their ocular condition were the main reasons that patients were not motivated to use such service facilities. Statistically significant differences were observed when past utilization of eye care camps was related to age, marital status, and source of income.

Adult↗
PubMed1995

A community-based evaluation of eyesight and spectacle use after intracapsular cataract extraction in northern India.

The visual outcome and extent of aphakic spectacle use at community level was evaluated in 177 patients who underwent ICCE in peripheral camps. In 16.9%, both eyes were operated. The mean age at cataract surgery was 63 years (range 33-82 years). After surgery, 79.7% had better vision; 72.3% were extremely satisfied with the surgical outcome. Of those with improved or similar vision, 81.9% were regularly using aphakic spectacles. Free aphakic spectacles after surgery were received by 57.6%. Broken spectacles was the most common cause for not using or intermittently using spectacles. The major benefits to patients were the ability to undertake personal activities, improved mobility and recognition of family members, friends and cattle.

Adult↗
PubMed1994

Evaluation of an innovative school eye health educational mode.

An innovative mode of using school children as health educators for transmitting messages on eye health care in the school environment was evaluated. Fifty children were evaluated at baseline and immediately after the educational session. A significant change in cognitive aspects of eye care was demonstrated (p < 0.001). Knowledge on vitamin A related aspects and childhood ocular trauma improved substantially compared to all other aspects of eye care.

Child↗
PubMed1994

Epidemiological aspects of visual impairment above 50 years in a rural area.

A cross-sectional survey was conducted in 5 villages in central India to find out the extent, causes and epidemiological factors for visual impairment among 903 individuals aged above 50 years; 44.3% of them were visually impaired (29.4% with low vision and 14.9% blind). Age-specific visual impairment increased at a rate of 13.2% with each decade of advancing age. Landless labourers suffered more from visual impairment than other occupational groups (p < 0.05). Socioeconomic and literacy status of the population did not significantly influence the prevalence of visual impairment. Major causes of visual impairment were cataract (48.5%), refractive errors (24.5%), age-related macular degeneration (10%), glaucoma (6.8%), and others (10.2%). In view of the high prevalence of visual impairment among the elderly individuals, it is necessary to intensify our efforts in motivating them for early detection and treatment.

Aged↗