Biomedical subjects
Publications and source records attributed to G V Murthy.
Conjunctival impression cytology was used to determine the extent of preclinical and clinical vitamin A deficiency in school children aged 8-13 years. Nearly 23% of the examined children had an abnormal cytology reflecting a poor vitamin A status. The differences in cytology results were not significantly affected by either age or sex.
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The incidence of low birth weight (less than or equal to 2500 g) was 38.9% among 2292 singleton live births at a rural project hospital in Haryana. Only 7.0% of the newborns weighed 2000 g or less. Female babies had a higher incidence of low birth weight. Other factors considered were maternal age, parity and literacy and father's literacy. Young mothers (less than 20 years) had a higher incidence of low birth weight. Similarly parents who were illiterate or educated to below the primary grade also had a higher incidence of low birth weight. The maximum percentage of low birth weight was seen in the primiparous mothers. An increase of low birth weight was also seen after the 4th parity. The best outcome was at para 4.
The prevalence of vitamin A deficiency was estimated in 366 rural children in the age group of 1 to 15 years. In a systematically selected subsample of 90 children, the dietary intake of vitamin A was assessed. The prevalence of vitamin A deficiency signs ranged from 24.1 to 34.8%. The adequacy of dietary intake of vitamin A ranged from 8 to 12% when compared with the recommended dietary allowance. The dietary intake of children with and without vitamin A deficiency was not different (p greater than 0.05). The main source of beta carotene in the diet was cereals accounting for 47.9% of the total beta carotene intake.
The defaecation habits of 172 adults before and after a cholera epidemic in New Delhi in 1988 were investigated. Intensive educational activities were undertaken during the epidemic. A community latrine facility was constructed in this area in February 1988. A greater proportion of females than males were found to be exclusively using the latrines at both rounds of the investigation. A statistically significant relationship with age was observed (P less than 0.001), while literacy was not found to exert a statistically significant effect. Difference in usage habits were more marked in the second round of the investigation. Cost and distance were the main reasons cited for non-utilization of latrines. 91.4% of respondents stated that they had faced some problem in using latrines. Most children were found to be defaecating in the open around the dwelling units at both rounds of the investigation.
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One hundred mothers of 'fully' immunized 12-24 month old children were administered a schedule to elicit knowledge regarding immunization. The mean age of the mothers was 27.05 years. Knowledge regarding vaccine availability was good, except in case of measles. A much lower proportion were aware of correct doses and intervals. Only DPT was reported to produce side-effects by a majority. The hypothesis that in a high coverage area, mothers would be armed with more specific immunization information was not borne out.
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A study on a few selected socio-biological determinants of birth weight was conducted at a rural project hospital in Haryana. Records of 2292 singleton live births over a period of two years (1985-1987) were analysed, by bivariate and multivariate methods. The mean birth weight of the infants was 2715 g (S.D. 453). Mean birth weight of male infants was 92 g more than female infants. Literacy levels of both parents, maternal age, parity, place of residence and antenatal care were found to have significant influence on the birthweight. Multiple regression showed that maternal age, maternal literacy and place of residence had minimal influence on the birth weight compared to other factors.
One hundred and six mothers in a rural area were interviewed to determine as to how they recognise pneumonia in children, what therapies they practice with mild acute respiratory illnesses and pneumonias and the feeding practices they adopt. Most mothers recognised pneumonia by noticing fast respiratory rate and difficulty in breathing. More severe cases were recognised by these signs among a higher percentage of mothers. As regards management of mild ARI episodes, more than half the mothers preferred not to give any treatment or use only home remedies. In pneumonias, a majority of them preferred to consult a qualified doctor. Nearly a third of them were of the opinion that they would take the child to hospital if the disease was severe. Regarding feeding practices, most of them stated that they would continue feeding, fluids and breast feeds. Only 10% desired to stop and another 15% would decrease the amounts.
This is a cost descriptive study which estimates the cost of providing iron and vitamin A supplementation through the primary health care system in India. The norms for the primary health care workers were taken as per national norms. The costs included the proportionate cost of the building, workers' salary and the cost of the supplements. The total cost of providing iron supplementation through the PHC was estimated at Rs. 43,800. The cost per beneficiary for adult folifer was Rs. 3.60, for paediatric folifer was Rs. 2.90 and for syrup folifer, it was Rs. 15.50. The overall cost of providing iron and folic acid supplements to the "at risk" population was estimated as Rs 4.40 per beneficiary per year. The cost of vitamin A supplementation to under three through the PHC system was estimated at Rs. 3.20 per beneficiary per year. Both iron as well as vitamin A supplementation through the PHC system appear to be low cost interventions.
A study on industrial ocular morbidity was carried out in 6 industrial establishments at Saharanpur. The mean age of the respondents was 35.3 years. 58.2% were regular floor staff. 10.6% professed suffering from an industrial ocular injury. 60% of these injuries were sustained by ocular metallic trauma. 51.9% complained of ocular symptoms at the time of the survey. The frequency of ocular complaints increased with age. The point prevalence of ocular morbidity was 746.03/1000 industrial workers. Refractive errors were the commonest ocular condition (56.7%) observed, followed by Trachoma (32.6%). The highest prevalence of morbidity was recorded among workers above 44 years. Clerical and managerial personnel had higher prevalence compared to other jobs. Only 3.6% of the floor workers were using protective devices while on the job.
28,055 persons aged 50 yrs+ from seven states in India were surveyed by a rapid assessment technique for cataract blindness. The prevalence of bilateral blindness (vision < 6/60 in the better eye) was 11.68 percent (95% C.I. 10.54-12.81). The age-gender adjusted blindness prevalence rate was 11.04 percent (95% C.I. 11.033-11.044). Age and occupational status were associated with blindness prevalence. Cataract was the commonest cause of low vision and blindness in this population. Respondents aged 60-69 years had a 2.74 times higher risk, while those aged 70 years+ had a 4.86 times higher risk of being blind, compared to those 50-59 years. Productively employed individuals had lowest blindness rates. Blindness rates were five times higher among respondents who were not working and two times higher among those engaged solely in household activities. The prevalence of cataract was 43.32 percent (95% C.I. 41.14-45.50) among those aged 50+ years. The prevalence increased with increasing age. Gender did not influence the prevalence of cataract in the present survey. Extrapolating from the present survey, it is estimated that 11.9 million blind people (vision < 6/60 in the better eye) in India are in urgent need of cataract surgery.
BACKGROUND: Although cataract accounts for half the blindness in the world, the resources available are not sufficient to meet the existing need for operations. The most effective low cost cataract surgery is probably performed in community camps. METHODS: We estimated the costs incurred in performing cataract operations in makeshift comprehensive eye care camps. Both the capital and recurrent inputs were costed at current market rates. RESULTS: Rupees 1,508,600 (US$ 47,100) was spent on conducting 17 camps during April 1992 to March 1993. Recurrent inputs were responsible for 83% of the total costs. Sixty per cent of the recurrent inputs were borne by non-governmental organizations. The total capital expenditure was borne by the mobile ophthalmic units. Food and drugs for patients (40%), and staff salaries and allowances (35%) were the major recurrent expenditure, while 60% of the capital expenditure was accounted for by vehicles. The unit cost of cataract surgery was Rs 772 (US$ 23). CONCLUSIONS: We suggest that comprehensive eye camps are cost-effective.