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Biomedical subjects

H A Wexler

Publications and source records attributed to H A Wexler.

7 recordsLinked to original sources

The persistent loop sign in neonatal necrotizing enterocolitis: a new indication for surgical intervention?

A new radiographic sign in neonatal necrotizing enterocolitis is described. Five patients with necrotizing enterocolitis exhibited an unchanging dilated loop of small bowel, which was followed by perforation in 3 infants; the other 2 had surgical and/or autopsy corroboration of profound bowel-wall necrosis. It is suggested that infants with a "persistent loop" be considered candidates for laparotomy.

Enterocolitis, Pseudomembranous

Congenital cystic adenomatoid malformation. A report of three unusual cases.

Most children with congenital cystic adenomatoid malformation present in the first six months of life. Three cases are described with unusually late presentation. One child was completely asymptomatic and another became symptomatic only after secondary infection of a congenital cystic adenomatoid malformation. In two cases the correct diagnosis was not made preoperatively. The value of preoperative lung scanning was demonstrated in one case in which a lung scan showed a larger perfused area than indicated on the radiograph. At operation, a lobulated cystic structure was seen attached by a thin pedicle to the interior surface of the left upper lobe.

Child, Preschool

Renal cyst puncture: a non-diagnostic procedure in the infant.

A case of metastatic Wilms tumor in a newborn is presented. Cyst puncture was included in the preoperative evaluation and the merits of this procedure in infants are questioned. The differential diagnosis of intrarenal masses in the neonate is discussed.

Female

Neonatal diaphragmatic dysfunction.

Several unusual diaphragmatic problems in the neonate are presented and a new potential complication of the negative pressure respirator is illustrated. The association of bilateral diaphragmatic eventrations with chromosome anomalies is emphasized. In our experience the appearance of the chest on frontal and lateral views is usually so characteristic that no further evaluation is required. The relationship between several neuromuscular disorders and diaphragmatic dysfunction is discussed. A case of congenital myotonic dystrophy with unilateral eventration is illustrated.

Chromosomes, Human, 13-15

The association of Wilms' tumor with second primary malignancies.

Medulloblastoma occurs uncommonly in the neonatal period. Metastatic Wilm's tumor in a newborn is extremely rare. The coincidence of these two neoplasms in one infant, and an equally uncommon combination of Wilms' tumor and a cerebellar medulloephithelioma in another child prompted this report. The authors speculate on the mechanism of oncogenesis in these and other infants with neonatal malignancies.

Cerebellar Neoplasms